Species

KNApSAcK Entry

Organism name Inocybe napipes
Genus Inocybe
Family Inocybaceae
Kingdom Fungi

NCBI taxonomy

Entry

Linked NCBI taxonomy name Inocybe napipes
Linked NCBI taxonomy ID 226590
Linked level species

Family

Family in NCBI taxonomy
ID

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Fungi
ID 4751

Plant class

Plant class
ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001422 External link 512 Muscarine
CHEMBL12587
CHEMBL105471
CHEMBL404094
CHEMBL1180201
D009116
12 / 8 / 5 0 / 1 No. 5425

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001422 1 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00001422 3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001422 0 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00001422 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00001422 0 / 0
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00001422 1 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001422 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001422 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00001422 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001422 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001422 0 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00001422 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (8)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#103780 Alcohol dependence P08172
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#608516 Major depressive disorder; mdd P08172

KEGG DISEASE (5)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D019966 Substance-Related Disorders C00001422