Coffea eugenioides

• Index
• Plant Species
• Metabolite list (6)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Coffea eugenioides
Genus	Coffea
Family	Rubiaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Coffea eugenioides
Linked NCBI taxonomy ID	49369
Linked level	species

Family

Family in NCBI taxonomy	Rubiaceae
ID	24966

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (6)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00033727	Clerosterol / (-)-Clerosterol / (-)-(3beta,24S)-Stigmasta-5,25-dien-3-ol	CHEMBL252365				No. 53	No. 11
C00003672	Sitosterol / beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol	CHEMBL221542 CHEMBL1398443 CHEMBL1875388		17 / 19 / 12		No. 53	No. 11
C00032163	Sitostanol / Stigmastanol / beta-Sitostanol	CHEMBL305498 CHEMBL252364	C021255			No. 68	No. 11
C00007322	delta7-Avenasterol					No. 111	No. 11
C00033758	delta7 Stigmastenol / (3beta)-Stigmast-7-en-3-ol	CHEMBL238597	C031313			No. 111	No. 11
C00001492	Caffeine	CHEMBL113	D002110	115 / 59 / 49	109 / 161	No. 3446	No. 12

Human Protein / Gene in interactions

124 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001492 C00003672	1 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001492 C00003672	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001492 C00003672	1 / 1
P03372	Estrogen receptor	NR3A1	C00001492 C00003672	1 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001492 C00003672	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00001492 C00003672	0 / 1
P08183	Multidrug resistance protein 1	drug	C00001492 C00003672	1 / 0
P06746	DNA polymerase beta	Enzyme	C00001492 C00003672	0 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00001492	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00001492	0 / 3
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00001492	2 / 2
P08246	Neutrophil elastase	S1A	C00001492	2 / 1
P33765	Adenosine receptor A3	Adenosine receptor	C00001492	0 / 0
P78527	DNA-dependent protein kinase catalytic subunit	Atypical serine/threonine protein kinase PIKK subfamily	C00001492	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00001492	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00001492	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00001492	0 / 0
Q9Y2T3	Guanine deaminase	Enzyme	C00001492	0 / 0
P29466	Caspase-1	C14	C00001492	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00001492	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00001492	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00001492	2 / 2
Q13315	Serine-protein kinase ATM	Atypical serine/threonine protein kinase PIKK subfamily	C00001492	1 / 4
O15245	Solute carrier family 22 member 1	Drug uniporter	C00001492	0 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00003672	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00003672	3 / 2
P10828	Thyroid hormone receptor beta	NR1A2	C00001492	3 / 1
P29275	Adenosine receptor A2b	Adenosine receptor	C00001492	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00001492	1 / 2
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00001492	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00001492	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00001492	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00001492	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00001492	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00001492	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00001492	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00001492	0 / 0
P02768	Serum albumin	Secreted protein	C00001492	0 / 0
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003672	2 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00001492	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00001492	0 / 0
Q08828	Adenylate cyclase type 1	Enzyme	C00001492	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00001492	0 / 0
O94956	Solute carrier organic anion transporter family member 2B1	Unclassified protein	C00001492	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00001492	1 / 8
P14416	D(2) dopamine receptor	Dopamine receptor	C00001492	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00001492	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00001492	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00001492	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00001492	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00001492	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00001492	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00001492	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00001492	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00001492	1 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00001492	0 / 0
O75496	Geminin	Unclassified protein	C00001492	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00001492	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00001492	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00001492	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00001492	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00001492	1 / 0
P27338	Amine oxidase [flavin-containing] B	Oxidoreductase	C00001492	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00001492	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00001492	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00001492	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00001492	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00001492	1 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00003672	0 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00001492	0 / 0
P08311	Cathepsin G	S1A	C00001492	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00001492	1 / 0
P03956	Interstitial collagenase	M10A	C00001492	0 / 1
Q13535	Serine/threonine-protein kinase ATR	Atypical serine/threonine protein kinase PIKK subfamily	C00001492	2 / 2
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00001492	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00001492	0 / 0
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00001492	1 / 0
P00734	Prothrombin	S1A	C00003672	4 / 2
P04150	Glucocorticoid receptor	NR3C1	C00001492	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00001492	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00001492	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00003672	4 / 2
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00001492	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00001492	2 / 0
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00001492	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00001492	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00001492	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00001492	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00001492	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00001492	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00001492	1 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00001492	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00001492	2 / 1
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00001492	1 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00001492	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00003672	0 / 0
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00001492	1 / 0
P22303	Acetylcholinesterase	Hydrolase	C00001492	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00001492	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00001492	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00001492	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00001492	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00001492	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00001492	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00001492	0 / 0
P42345	Serine/threonine-protein kinase mTOR	Enzyme	C00001492	0 / 0
P11217	Glycogen phosphorylase, muscle form	Enzyme	C00001492	1 / 1
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00001492	0 / 0
P10275	Androgen receptor	NR3C4	C00001492	3 / 4
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00001492	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00001492	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00001492	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00001492	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00001492	1 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00001492	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00001492	0 / 0
P04156	Major prion protein	Surface antigen	C00001492	6 / 2
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00003672	1 / 1
Q9UBT6	DNA polymerase kappa	Enzyme	C00001492	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00001492	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00003672	1 / 1
Q9NY46	Sodium channel protein type 3 subunit alpha	SCN alpha, NaV1.x	C00001492	0 / 0
Q99250	Sodium channel protein type 2 subunit alpha	SCN alpha, NaV1.x	C00001492	2 / 2
P35498	Sodium channel protein type 1 subunit alpha	SCN alpha, NaV1.x	C00001492	3 / 2

109 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
39	ACAT2	acetyl-CoA acetyltransferase 2 (EC:2.3.1.9)	C00001492
22985	ACIN1, ACINUS, ACN, fSAP152	apoptotic chromatin condensation inducer 1	C00001492
2181	ACSL3, ACS3, FACL3, PRO2194	acyl-CoA synthetase long-chain family member 3 (EC:6.2.1.3)	C00001492
135	ADORA2A, A2aR, ADORA2, RDC8	adenosine A2a receptor	C00001492
136	ADORA2B, ADORA2	adenosine A2b receptor	C00001492
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00001492
5832	ALDH18A1, ARCL3A, GSAS, P5CS, PYCS	aldehyde dehydrogenase 18 family, member A1 (EC:1.2.1.41 2.7.2.11)	C00001492
283	ANG, ALS9, HEL168, RNASE4, RNASE5	angiogenin, ribonuclease, RNase A family, 5 (EC:3.1.27.-)	C00001492
335	APOA1	apolipoprotein A-I	C00001492
336	APOA2, Apo-AII, ApoA-II, apoAII	apolipoprotein A-II	C00001492
338	APOB, FLDB, LDLCQ4	apolipoprotein B	C00001492
341	APOC1	apolipoprotein C-I	C00001492
344	APOC2, APO-CII, APOC-II	apolipoprotein C-II	C00001492
345	APOC3, APOCIII, HALP2	apolipoprotein C-III	C00001492
23204	ARL6IP1, AIP1, ARL6IP, ARMER	ADP-ribosylation factor-like 6 interacting protein 1	C00001492
440	ASNS, TS11	asparagine synthetase (glutamine-hydrolyzing) (EC:6.3.5.4)	C00001492
472	ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1	ataxia telangiectasia mutated (EC:2.7.11.1)	C00001492
9551	ATP5J2, ATP5JL	ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 (EC:3.6.1.14)	C00001492
545	ATR, FCTCS, FRP1, MEC1, SCKL, SCKL1	ataxia telangiectasia and Rad3 related (EC:2.7.11.1)	C00001492
581	BAX, BCL2L4	BCL2-associated X protein	C00001492
27113	BBC3, JFY-1, JFY1, PUMA	BCL2 binding component 3	C00001492
637	BID, FP497	BH3 interacting domain death agonist	C00001492
699	BUB1, BUB1A, BUB1L, hBUB1	BUB1 mitotic checkpoint serine/threonine kinase (EC:2.7.11.1)	C00001492
813	CALU	calumenin	C00001492
823	CAPN1, CANP, CANP1, CANPL1, muCANP, muCL	calpain 1, (mu/I) large subunit (EC:3.4.22.52)	C00001492
835	CASP2, CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57	caspase 2, apoptosis-related cysteine peptidase (EC:3.4.22.55)	C00001492
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00001492
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00001492
891	CCNB1, CCNB	cyclin B1	C00001492
995	CDC25C, CDC25, PPP1R60	cell division cycle 25C (EC:3.1.3.48)	C00001492
983	CDK1, CDC2, CDC28A, P34CDC2	cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22)	C00001492
1017	CDK2, p33(CDK2)	cyclin-dependent kinase 2 (EC:2.7.11.22)	C00001492
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00001492
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00001492
1111	CHEK1, CHK1	checkpoint kinase 1 (EC:2.7.11.1)	C00001492
11200	CHEK2, CDS1, CHK2, HuCds1, LFS2, PP1425, RAD53, hCds1	checkpoint kinase 2 (EC:2.7.11.1)	C00001492
1508	CTSB, APPS, CPSB	cathepsin B (EC:3.4.22.1)	C00001492
1537	CYC1, MC3DN6, UQCR4	cytochrome c-1	C00001492
54205	CYCS, CYC, HCS, THC4	cytochrome c, somatic	C00001492
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00001492
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00001492
1565	CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1	cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1)	C00001492
1571	CYP2E1, CPE1, CYP2E, P450-J, P450C2E	cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7)	C00001492
1580	CYP4B1, CYPIVB1, P-450HP	cytochrome P450, family 4, subfamily B, polypeptide 1 (EC:1.14.14.1)	C00001492
1603	DAD1, OST2	defender against cell death 1 (EC:2.4.99.18)	C00001492
1638	DCT, TRP-2, TYRP2	dopachrome tautomerase (EC:5.3.3.12)	C00001492
1813	DRD2, D2DR, D2R	dopamine receptor D2	C00001492
10209	EIF1, A121, EIF-1, EIF1A, ISO1, SUI1	eukaryotic translation initiation factor 1	C00001492
1978	EIF4EBP1, 4E-BP1, 4EBP1, BP-1, PHAS-I	eukaryotic translation initiation factor 4E binding protein 1	C00001492
2688	GH1, GH, GH-N, GHN, IGHD1B, hGH-N	growth hormone 1	C00001492
2745	GLRX, GRX, GRX1	glutaredoxin (thioltransferase) (EC:1.8.4.1)	C00001492
55830	GLT8D1, MSTP139	glycosyltransferase 8 domain containing 1	C00001492
2746	GLUD1, GDH, GDH1, GLUD	glutamate dehydrogenase 1 (EC:1.4.1.3)	C00001492
2932	GSK3B	glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)	C00001492
9446	GSTO1, GSTO_1-1, GSTTLp28, P28, SPG-R	glutathione S-transferase omega 1 (EC:2.5.1.18 1.8.5.1 1.20.4.2)	C00001492
3014	H2AFX, H2A.X, H2A/X, H2AX	H2A histone family, member X	C00001492
3291	HSD11B2, AME, AME1, HSD11K, HSD2, SDR9C3	hydroxysteroid (11-beta) dehydrogenase 2 (EC:1.1.1.146)	C00001492
3484	IGFBP1, AFBP, IBP1, IGF-BP25, PP12, hIGFBP-1	insulin-like growth factor binding protein 1	C00001492
3630	INS, IDDM2, ILPR, IRDN, MODY10	insulin	C00001492
3708	ITPR1, INSP3R1, IP3R, IP3R1, SCA15, SCA16, SCA29	inositol 1,4,5-trisphosphate receptor, type 1	C00001492
3939	LDHA, GSD11, LDH1, LDHM	lactate dehydrogenase A (EC:1.1.1.27)	C00001492
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00001492
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00001492
4257	MGST1, GST12, MGST, MGST-I	microsomal glutathione S-transferase 1 (EC:2.5.1.18)	C00001492
4277	MICB, PERB11.2	MHC class I polypeptide-related sequence B	C00001492
4495	MT1G, MT1, MT1K	metallothionein 1G	C00001492
2475	MTOR, FRAP, FRAP1, FRAP2, RAFT1, RAPT1	mechanistic target of rapamycin (serine/threonine kinase) (EC:2.7.11.1)	C00001492
10	NAT2, AAC2, NAT-2, PNAT	N-acetyltransferase 2 (arylamine N-acetyltransferase) (EC:2.3.1.5)	C00001492
4942	OAT, GACR, HOGA, OATASE, OKT	ornithine aminotransferase (EC:2.6.1.13)	C00001492
5062	PAK2, PAK65, PAKgamma	p21 protein (Cdc42/Rac)-activated kinase 2 (EC:2.7.11.1)	C00001492
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00001492
5354	PLP1, GPM6C, HLD1, MMPL, PLP, PLP/DM20, PMD, SPG2	proteolipid protein 1	C00001492
5521	PPP2R2B, B55BETA, PP2AB55BETA, PP2ABBETA, PP2APR55B, PP2APR55BETA, PR2AB55BETA, PR2ABBETA, PR2APR55BETA, PR52B, PR55-BETA, PR55BETA, SCA12	protein phosphatase 2, regulatory subunit B, beta (EC:3.1.3.16)	C00001492
27166	PRELID1, PRELI, PX19, SBBI12	PRELI domain containing 1	C00001492
5591	PRKDC, DNA-PKcs, DNAPK, DNPK1, HYRC, HYRC1, XRCC7, p350	protein kinase, DNA-activated, catalytic polypeptide (EC:2.7.11.1)	C00001492
5621	PRNP, ASCR, AltPrP, CD230, CJD, GSS, KURU, PRIP, PrP, PrP27-30, PrP33-35C, PrPc, p27-30	prion protein	C00001492
10197	PSME3, Ki, PA28-gamma, PA28G, PA28gamma, REG-GAMMA	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)	C00001492
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00001492
5925	RB1, OSRC, RB, p105-Rb, pRb, pp110	retinoblastoma 1	C00001492
5972	REN, HNFJ2	renin (EC:3.4.23.15)	C00001492
6194	RPS6, S6	ribosomal protein S6	C00001492
6197	RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2	ribosomal protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1)	C00001492
6198	RPS6KB1, PS6K, S6K, S6K-beta-1, S6K1, STK14A, p70_S6KA, p70(S6K)-alpha, p70-S6K, p70-alpha	ribosomal protein S6 kinase, 70kDa, polypeptide 1 (EC:2.7.11.1)	C00001492
23212	RRS1	RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)	C00001492
6261	RYR1, CCO, MHS, MHS1, RYDR, RYR, RYR-1, SKRR	ryanodine receptor 1 (skeletal)	C00001492
23256	SCFD1, C14orf163, RA410, SLY1, SLY1P, STXBP1L2	sec1 family domain containing 1	C00001492
6396	SEC13, D3S1231E, SEC13L1, SEC13R, npp-20	SEC13 homolog (S. cerevisiae)	C00001492
10484	SEC23A, CLSD	Sec23 homolog A (S. cerevisiae)	C00001492
5265	SERPINA1, A1A, A1AT, AAT, PI, PI1, PRO2275, alpha1AT	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1	C00001492
866	SERPINA6, CBG	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6	C00001492
6566	SLC16A1, HHF7, MCT, MCT1	solute carrier family 16 (monocarboxylate transporter), member 1	C00001492
54498	SMOX, C20orf16, PAO, PAO-1, PAOH1, SMO	spermine oxidase (EC:1.5.3.16)	C00001492
6713	SQLE	squalene epoxidase (EC:1.14.13.132)	C00001492
8878	SQSTM1, A170, OSIL, PDB3, ZIP3, p60, p62, p62B	sequestosome 1	C00001492
6426	SRSF1, ASF, SF2, SF2p33, SFRS1, SRp30a	serine/arginine-rich splicing factor 1	C00001492
6770	STAR, STARD1	steroidogenic acute regulatory protein	C00001492
55342	STRBP, ILF3L, SPNR, p74	spermatid perinuclear RNA binding protein	C00001492
7027	TFDP1, DP1, DRTF1, Dp-1	transcription factor Dp-1	C00001492
10548	TM9SF1, HMP70, MP70	transmembrane 9 superfamily member 1	C00001492
9911	TMCC2, HUCEP11	transmembrane and coiled-coil domain family 2	C00001492
27346	TMEM97, MAC30	transmembrane protein 97	C00001492
7292	TNFSF4, CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1	tumor necrosis factor (ligand) superfamily, member 4	C00001492
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00001492
7296	TXNRD1, GRIM-12, TR, TR1, TRXR1, TXNR	thioredoxin reductase 1 (EC:1.8.1.9)	C00001492
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00001492
7385	UQCRC2, MC3DN5, QCR2, UQCR2	ubiquinol-cytochrome c reductase core protein II (EC:1.10.2.2)	C00001492
7498	XDH, XO, XOR	xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2)	C00001492
10971	YWHAQ, 14-3-3, 1C5, HS1	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide	C00001492
7587	ZNF37A, KOX21, ZNF37	zinc finger protein 37A	C00001492

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Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions