| Organism name | Pancratium canariense |
|---|---|
| Genus | Pancratium |
| Family | Amaryllidaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Pancratium canariense |
|---|---|
| Linked NCBI taxonomy ID | 112571 |
| Linked level | species |
| Family in NCBI taxonomy | Amaryllidaceae |
|---|---|
| ID | 4668 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | Liliopsida |
|---|---|
| ID | 4447 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00001571
|
Haemanthamine
|
CHEMBL401114
CHEMBL516991 CHEMBL1172810 CHEMBL1221865 CHEMBL1551610 CHEMBL1995397 |
C462104
|
5 / 6 / 3 | No. 103 | No. 4 |
|
|
|
C00047331
|
Pancratinine C
/ (-)-Pancratinine C |
No. 103 | No. 4 |
|
||||
|
C00047330
|
Pancratinine B
/ (+)-Pancratinine B |
No. 103 | No. 4 |
|
||||
|
C00024425
|
Pancratine
/ Haemanthidine |
CHEMBL404212
CHEMBL512669 CHEMBL465820 CHEMBL1169873 CHEMBL1172881 CHEMBL2006644 |
C083906
|
1 / 1 / 0 | No. 103 | No. 4 |
|
|
|
C00024438
|
Tazettine
/ (+)-Tazettine |
CHEMBL457605
CHEMBL1720510 CHEMBL1997188 |
C011361
|
6 / 1 / 0 | No. 103 | No. 4 |
|
|
|
C00047153
|
6-O-Methylhaemanthidine
|
CHEMBL2087243
|
No. 103 | No. 4 |
|
|||
|
C00024446
|
Vittatine
|
CHEMBL469648
CHEMBL1221864 CHEMBL1971343 |
3 / 1 / 0 | No. 103 | No. 4 |
|
||
|
C00027661
|
11-Hydroxyvittatine
|
No. 251 |
|
|||||
|
C00001572
|
Hippeastrine
|
CHEMBL457606
CHEMBL1333401 CHEMBL1515264 |
C060577
|
8 / 3 / 4 | No. 715 |
|
||
|
C00047329
|
Pancratinine A
/ (+)-Pancratinine A |
No. 715 |
|
|||||
|
C00024441
|
Ungiminorine
/ Deacetyllutessine / O-Deacetyllutessine |
CHEMBL497276
|
1 / 1 / 0 | No. 860 | No. 4 |
|
||
|
C00047332
|
Pancratinine D
/ (-)-Pancratinine D |
No. 991 |
|
|||||
|
C00001576
|
Lycorine
/ (-)-Lycorine |
CHEMBL224745
CHEMBL400092 CHEMBL583716 CHEMBL577635 CHEMBL1592744 CHEMBL1593638 |
C015330
|
20 / 24 / 18 | 5 / 5 | No. 1156 | No. 4 |
|
|
C00028793
|
Pancracine
/ (-)-Hippagine |
CHEMBL2002715
|
No. 1156 | No. 4 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P22303 | Acetylcholinesterase | Hydrolase | C00001571 C00001576 C00024425 C00024438 C00024441 C00024446 | 1 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001571 C00001572 C00001576 | 0 / 1 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00001576 C00024446 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00001572 C00001576 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001572 C00001576 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001572 C00001576 | 0 / 1 |
| Q99700 | Ataxin-2 | Unclassified protein | C00001572 C00001576 | 1 / 1 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00001576 C00024446 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001572 C00001576 | 1 / 1 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00001571 C00001576 | 4 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001572 C00001576 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00001571 C00001576 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001571 C00001576 | 1 / 1 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00024438 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00024438 | 0 / 0 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00001576 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00024438 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001572 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001576 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00001576 | 2 / 3 |
| P02545 | Prelamin-A/C | Unclassified protein | C00001576 | 11 / 10 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00024438 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00001576 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00001576 | 2 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001576 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00024438 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 896 | CCND3 | cyclin D3 |
C00001576
|
| 1003 | CDH5, 7B4, CD144 | cadherin 5, type 2 (vascular endothelium) |
C00001576
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00001576
|
| 10507 | SEMA4D, C9orf164, CD100, M-sema-G, SEMAJ, coll-4 | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D |
C00001576
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00001576
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #112100 | Yt blood group antigen |
P22303
|
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |