Species

KNApSAcK Entry

Organism name Aconitum deiphinifolium
Genus Aconitum
Family Ranunculaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Aconitum
Linked NCBI taxonomy ID 49188
Linked level genus

Family

Family in NCBI taxonomy Ranunculaceae
ID 3440

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001621 External link 512 Browniine
No. 31 No. 10
C00001627 External link 512 Kondelfin
/ Condelphine
CHEMBL343843
CHEMBL1242535
CHEMBL1741540
5 / 2 / 3 No. 31 No. 10
C00001632 External link 512 Delcosine
CHEMBL2141282
2 / 7 / 3 No. 31 No. 10
C00028417 External link 512 Isotalatizidine
CHEMBL1242437
C423465
No. 31 No. 10
C00035206 External link 512 14-O-Acetylsachaconitine
No. 31 No. 10

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001627 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001627 0 / 1
O75496 Geminin Unclassified protein C00001632 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00001632 7 / 3
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001627 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001627 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001627 0 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092

KEGG DISEASE (6)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)