KCF-S cluster No. 31 (111 metabolites)

Corresponding Phytochemical cluster No. 10

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (111)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count
eudicotyledons	255
Embryophyta	4
asterids	2
rosids	1

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Cumulative family count

class name	count
Ranunculaceae	255
Lycopodiaceae	4
Asteraceae	1
Salicaceae	1
Boraginaceae	1

KEGG BRITE br08003

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Categories (1)

br08003 Category	# of metabolite
Terpenoid alkaloids	10

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metabolites link (11)

br08003 Category	KEGG ID	KNApSAcK ID
Terpenoid alkaloids	C08654	C00001609
Terpenoid alkaloids	C08667	C00001623
Terpenoid alkaloids	C08671	C00001627
Terpenoid alkaloids	C08675	C00001631
Terpenoid alkaloids	C08676	C00001632
Terpenoid alkaloids	C08678	C00001634
Terpenoid alkaloids	C08693	C00001649
Terpenoid alkaloids	C08697	C00001653
Terpenoid alkaloids	C08713	C00001669
Terpenoid alkaloids	C08715	C00001671
Terpenoid alkaloids	C08654	C00027972

Metabolite list (111)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00001609	Acetylbrowniine	CHEMBL398904
C00001621	Browniine
C00001622	Cammaconine		C046734
C00001623	Cardiopetalidine
C00001627	Kondelfin / Condelphine	CHEMBL343843 CHEMBL1242535 CHEMBL1741540		5 / 2 / 3
C00001631	Delcorine	CHEMBL1396858 CHEMBL1742074 CHEMBL1868972 CHEMBL2112852		8 / 4 / 3
C00001632	Delcosine	CHEMBL2141282		2 / 7 / 3
C00001634	Delsoline	CHEMBL1242534 CHEMBL1474356 CHEMBL2112855	C045308	8 / 15 / 13
C00001649	Karakoline	CHEMBL1242438 CHEMBL1496845 CHEMBL1513445 CHEMBL1514236 CHEMBL1525359 CHEMBL1872961		8 / 14 / 15
C00001653	Lycoctonine / (+)-Lycoctonine	CHEMBL517003 CHEMBL1242718 CHEMBL1303310 CHEMBL1975737 CHEMBL2356607	C093992	3 / 10 / 7
C00001669	Talatisamine / Talatizamine		C069834
C00001671	Tricornine
C00027652	10-Hydroxyperegrine
C00027664	12beta-Hydroxykarasamine
C00027680	14-Acetyldelcosine / 4-O-Acetyldelcosine	CHEMBL399468
C00027681	14-Acetylperegrine / 14-O-Acetylperegrine
C00027682	14-Acetylvirescenine	CHEMBL1242624
C00027684	Dehydrobrowniine / 14-Dehydrobrowniine	CHEMBL2136823
C00027685	14-Dehydrodelcosine
C00027687	Bullatine B / 14-O-Acetylneoline
C00027691	Fuziline / Senbusine C / 15alpha-Hydroxyneoline
C00027770	Peregrine alcohol / 6-Deacetylperegrine
C00027802	Acoforine
C00027804	Aconosine		C067326
C00027937	Bicoloridine alcohol
C00027946	Blacknidine / (+)-Blacknidine
C00027947	Blacknine / Delmenzine / O1-Demethyldelelatine
C00027972	14-Acetylbrowniine / Browniine 14-acetate / Browniine 14-O-acetate	CHEMBL398904
C00028038	Chasmanine
C00028080	Columbidine
C00028084	Consolidine / (+)-Consolidine / O-Deacetyl-14-O-methylpubescenine
C00028136	Dehydroacosanine / (+)-Dehydroacosanine
C00028138	Dehydrobicoloridine / (+)-Dehydrobicoloridine
C00028155	Delbrunine
C00028156	Delbrusine
C00028157	Delectinine	CHEMBL1242719
C00028158	Delelatine	CHEMBL254802
C00028159	Delpheline / 2,3-Dihydrodeacetyltatsiensine
C00028195	Dihydrogadesine
C00028277	Foresticine
C00028288	Fuziline
C00028303	Gigactonine	CHEMBL1242625
C00028417	Isotalatizidine	CHEMBL1242437	C423465
C00028464	Leroyine
C00028465	Leroyine 14-acetate / Leroyine 14-O-acetate
C00028471	Leucostine A
C00028472	Leucostine B
C00028595	Molline
C00028613	Munzianine
C00028671	Neoline	CHEMBL1242346
C00028672	Neolinine
C00028740	Nudicaulidine
C00028856	Potanine
C00028885	Pubescenine
C00028896	Raveyine
C00028951	Sachaconitine / Vilmorrianine D
C00028990	Senbusine A
C00029071	Takaosamine
C00029072	Talitine A / O1-Methyltalitine C
C00029073	Talitine B
C00029139	Tongolenine D / (+)-Tongolenine D
C00029140	Tongoline
C00029224	Virescenine
C00029410	18-Acetylcammaconine
C00029967	Circinadine B
C00031096	Pseudaconine
C00031518	18-Demethoxypubescenine
C00031519	18-Demethylpubescenine / 18-O-Demethylpubescenine
C00031520	18-Hydroxy-14-O-methylgadesine / 18-Hydroxy-14-O-methyl-gadesine
C00031521	18-Methoxygadesine
C00031725	Dehydrodelsoline / Anhydrohydroxydelsoline
C00031726	Dehydrodeltatsine
C00031727	Delbonine
C00031729	Deltatsine
C00031851	Hemsleyatine
C00032283	Talatizidine	CHEMBL1242437
C00034995	14-Acetyltalatizamine
C00035126	Linearilin
C00035192	10-Hydroxytalatizamine
C00035205	14-Acetylgenicunine B
C00035206	14-O-Acetylsachaconitine
C00035209	16beta-Hydroxycardiopetaline
C00035240	8-Ethoxysachaconitine
C00035290	Delphatine
C00035395	Swatinine
C00035461	14-Acetyldihydrogadesine
C00035587	Dihydropentagynine
C00035725	Pentagydine
C00035727	Pentagynine
C00037018	Delcaroline
C00037034	Deoxylycoctonine
C00037459	Macrocentridine
C00038170	16-Demethyldelsoline
C00038348	Acotoxicine
C00038779	Circinasine A
C00038783	Circinasine E
C00038784	Circinasine F
C00038962	Delavaconine
C00039040	Dolaconine / Episcopalitine		C067323
C00040927	Consolinine
C00040928	Crispulidine
C00040956	Ezochasmanine	CHEMBL2140549		1 / 0 / 0
C00040994	Hoheconsoline
C00045155	14-Demethyltuguaconitine / (+)-14-Demethyltuguaconitine
C00046560	14-Acetylchasmanine
C00046562	14-Demethyltuguaconitine / (+)-14-Demethyltuguaconitine
C00047306	Majusine B / (+)-Majusine B
C00047718	Ambiguine
C00049096	6-O-Acetyl-14-O-methyldelphinifoline
C00049097	6-O-Acetyldemethylenedelcorine
C00049099	8-Acetylcondelphine

Human Protein / Gene in interactions

15 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001627 C00001631 C00001634 C00001649	1 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001627 C00001631 C00001634 C00001649	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001627 C00001631 C00001634 C00001649	1 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00001627 C00001631 C00001634 C00001649	0 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001627 C00001631 C00001634 C00001649	0 / 0
O75496	Geminin	Unclassified protein	C00001631 C00001632 C00001634 C00040956	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00001632 C00001653	7 / 3
P02545	Prelamin-A/C	Unclassified protein	C00001634 C00001649	11 / 10
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00001631	0 / 0
P54132	Bloom syndrome protein	Enzyme	C00001649	1 / 2
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00001634	2 / 0
P11473	Vitamin D3 receptor	NR1I1	C00001653	2 / 3
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00001631	2 / 0
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00001649	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00001653	1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions