PCIDB

KNApSAcK Metabolite C00001653

Metabolite

KNApSAcK Entry

id C00001653
Name Lycoctonine / (+)-Lycoctonine
CAS RN 26000-17-9
Standard InChI InChI=1S/C25H41NO7/c1-6-26-11-22(12-27)8-7-16(31-3)24-14-9-13-15(30-2)10-23(28,17(14)18(13)32-4)25(29,21(24)26)20(33-5)19(22)24/h13-21,27-29H,6-12H2,1-5H3/t13-,14-,15+,16+,17-,18+,19-,20+,21?,22?,23-,24+,25-/m1/s1
Standard InChI (Main Layer) InChI=1S/C25H41NO7/c1-6-26-11-22(12-27)8-7-16(31-3)24-14-9-13-15(30-2)10-23(28,17(14)18(13)32-4)25(29,21(24)26)20(33-5)19(22)24/h13-21,27-29H,6-12H2,1-5H3

Cluster

Phytochemical cluster No. 10
KCF-S cluster No. 31

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL517003 CHEMBL1242718 CHEMBL1303310 CHEMBL1975737 CHEMBL2356607

KEGG

By LinkDB C08697

CTD

By CAS RN C093992

Species

Summary

Plant class

class name count
eudicotyledons 13
Embryophyta 4
asterids 1

Family

family name count
Ranunculaceae 13
Lycopodiaceae 4
Asteraceae 1

List (19)

* NCBI
KNApSAcK organism *ID *family *plant class *kingdom
Aconitum finetianum Hand-Mazz. 49188 Ranunculaceae eudicotyledons Viridiplantae
Aconitum lycoctonum 112589 Ranunculaceae eudicotyledons Viridiplantae
Aconitum orientale Mill 49188 Ranunculaceae eudicotyledons Viridiplantae
Consolida axilliflora DC Schrod 37493 Ranunculaceae eudicotyledons Viridiplantae
Consolida hohenackeri 37493 Ranunculaceae eudicotyledons Viridiplantae
Delphinium consolida 46246 Ranunculaceae eudicotyledons Viridiplantae
Delphinium corymbosum Rgl. 46246 Ranunculaceae eudicotyledons Viridiplantae
Delphinium dictyocarpum DC. 46246 Ranunculaceae eudicotyledons Viridiplantae
Delphinium linearilobum 46246 Ranunculaceae eudicotyledons Viridiplantae
Delphinium majus 46246 Ranunculaceae eudicotyledons Viridiplantae
Delphinium nudicaule Torr.et Gray. 46246 Ranunculaceae eudicotyledons Viridiplantae
Delphinium pentagynum 1127184 Ranunculaceae eudicotyledons Viridiplantae
Delphinium scabriflorum 46246 Ranunculaceae eudicotyledons Viridiplantae
Inula royleana 41589 Asteraceae asterids Viridiplantae
Lycopodium clavatum var. megastachyon 3251 Lycopodiaceae Embryophyta Viridiplantae
Lycopodium gnidioides 3251 Lycopodiaceae Embryophyta Viridiplantae
Lycopodium paniculatum 3251 Lycopodiaceae Embryophyta Viridiplantae
Lycopodium serratum 355589 Lycopodiaceae Embryophyta Viridiplantae
Lycopoidium alpinum

Human Protein / Gene in interaction

3 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
P11473 Vitamin D3 receptor NR1I1 CHEMBL1303310 CHEMBL1794311 (1)
2 / 3
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL1303310 CHEMBL2114810 (1)
7 / 3
Q13148 TAR DNA-binding protein 43 Unclassified protein CHEMBL2356607 CHEMBL2354287 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#174800 Mccune-albright syndrome; mas P63092
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (7)

KEGG disease name UniProt
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)