Inula royleana

• Index
• Plant Species
• Metabolite list (17)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Inula royleana
Genus	Inula
Family	Asteraceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Inula
Linked NCBI taxonomy ID	41589
Linked level	genus

Family

Family in NCBI taxonomy	Asteraceae
ID	4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (17)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001653	Lycoctonine / (+)-Lycoctonine	CHEMBL517003 CHEMBL1242718 CHEMBL1303310 CHEMBL1975737 CHEMBL2356607	C093992	3 / 10 / 7		No. 31	No. 10
C00003306	Isohelenin / Isoalantolactone / Isoallantolactone	CHEMBL273254 CHEMBL137803 CHEMBL1410671 CHEMBL1451900 CHEMBL2000732	C032787	6 / 4 / 5		No. 69	No. 38
C00029526	4-epi-Isoinuviscolide					No. 69	No. 38
C00021698	8-epi-Isovangustin					No. 69	No. 38
C00021699	9beta-Hydroxy costunolide					No. 107	No. 38
C00020347	Carabrol / 4-Dihydrocarabrone					No. 144	No. 38
C00021695	Acetylivalin					No. 157	No. 38
C00001615	Anthranoyllycoctonine	CHEMBL359227 CHEMBL451362 CHEMBL1499239 CHEMBL1968141		11 / 33 / 28		No. 166	No. 10
C00021697	8-epi-Ivangustin					No. 178	No. 38
C00021704	4beta,5alpha-Epoxy-4,5-cis-inunolide					No. 227	No. 38
C00021701	9beta-(2-Methyl butyryloxy)-costunolide					No. 249	No. 38
C00021700	9beta-Propionyloxy costunolide					No. 249	No. 38
C00012896	2-Oxoalantolactone / [3aR-(3aalpha,5beta,8abeta,9aalpha)]-3,3a,5,6,8,8a,9,9a-Octahydro-5,8a-dimethyl-3-methylenenaphtho[2,3-b]furan-2,7-dione					No. 358	No. 38
C00012893	Eupatal / Alant camphor / Inula camphor / (+)-Alantolactone / Elecampane camphor	CHEMBL8831 CHEMBL136356 CHEMBL1592975	C004363	5 / 21 / 50	10 / 0	No. 358	No. 38
C00012895	2alpha-Hydroxy alantolactone	CHEMBL486020	C044996			No. 358	No. 38
C00003480	Royleanone	CHEMBL1813341				No. 792	No. 40
C00021709	4-Dihydrotomentosin	CHEMBL1912041 CHEMBL1912056				No. 857	No. 38

Human Protein / Gene in interactions

20 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00001615 C00001653	7 / 3
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00003306 C00012893	0 / 1
P03372	Estrogen receptor	NR3A1	C00003306 C00012893	1 / 1
P02545	Prelamin-A/C	Unclassified protein	C00001615 C00012893	11 / 10
P11473	Vitamin D3 receptor	NR1I1	C00001653 C00012893	2 / 3
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00003306	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00003306	0 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00001615	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00001615	2 / 2
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00001615	2 / 0
P07237	Protein disulfide-isomerase	Enzyme	C00001615	0 / 0
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00001615	1 / 2
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00001615	2 / 2
P04062	Glucosylceramidase	Enzyme	C00001615	6 / 4
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00003306	1 / 1
P04637	Cellular tumor antigen p53	Transcription Factor	C00012893	7 / 37
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00001615	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00003306	1 / 1
O00255	Menin	Unclassified protein	C00001615	2 / 5
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00001653	1 / 1

10 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
578	BAK1, BAK, BAK-LIKE, BCL2L7, CDN1	BCL2-antagonist/killer 1	C00012893
581	BAX, BCL2L4	BCL2-associated X protein	C00012893
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00012893
637	BID, FP497	BH3 interacting domain death agonist	C00012893
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00012893
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00012893
842	CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56	caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62)	C00012893
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00012893
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00012893
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00012893

Related Diseases

Diseases related to proteins in ChEMBL interactions