Delphinium majus

• Index
• Plant Species
• Metabolite list (22)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Delphinium majus
Genus	Delphinium
Family	Ranunculaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Delphinium
Linked NCBI taxonomy ID	46246
Linked level	genus

Family

Family in NCBI taxonomy	Ranunculaceae
ID	3440

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	eudicotyledons
ID	71240

Metabolite list (22)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001621	Browniine					No. 31	No. 10
C00001632	Delcosine	CHEMBL2141282		2 / 7 / 3		No. 31	No. 10
C00027685	14-Dehydrodelcosine					No. 31	No. 10
C00001653	Lycoctonine / (+)-Lycoctonine	CHEMBL517003 CHEMBL1242718 CHEMBL1303310 CHEMBL1975737 CHEMBL2356607	C093992	3 / 10 / 7		No. 31	No. 10
C00047306	Majusine B / (+)-Majusine B					No. 31	No. 10
C00027684	Dehydrobrowniine / 14-Dehydrobrowniine	CHEMBL2136823				No. 31	No. 10
C00027947	Blacknine / Delmenzine / O1-Demethyldelelatine					No. 31	No. 10
C00047305	Majusine A / (+)-Majusine A					No. 166	No. 10
C00028160	Delsemine A					No. 166	No. 10
C00028161	Delsemine B					No. 166	No. 10
C00043256	Ajacine	CHEMBL1240989				No. 166	No. 10
C00028578	Methyllycaconitine	CHEMBL223494 CHEMBL387362 CHEMBL510275 CHEMBL1412391 CHEMBL1592980 CHEMBL1620703 CHEMBL1869403 CHEMBL2094019	C054634	21 / 12 / 8	15 / 7	No. 166	No. 10
C00047304	Majusimine D / (-)-Majusimine D					No. 695
C00001635	Deltaline	CHEMBL1378039 CHEMBL1450099 CHEMBL2112845		6 / 2 / 3		No. 764	No. 10
C00029075	Tatsiensine		C067313			No. 764	No. 10
C00047301	Majusimine A / (-)-Majusimine A					No. 1192
C00047302	Majusimine B / (-)-Majusimine B					No. 1192
C00024875	Delgrandine / (-)-Delgrandine					No. 1192
C00047303	Majusimine C / (-)-Majusimine C					No. 1192
C00047299	Majusidine A / (-)-Majusidine A					No. 1571
C00047300	Majusidine B / (+)-Majusidine B					No. 1571
C00047307	Majusine C / (+)-Majusine C					No. 7970

Human Protein / Gene in interactions

26 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00001635 C00028578	1 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001635 C00028578	0 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00001635 C00028578	1 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00001635 C00028578	0 / 1
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00001632 C00001653	7 / 3
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00001635 C00028578	0 / 0
P43681	Neuronal acetylcholine receptor subunit alpha-4	CHRN alpha	C00028578	1 / 1
P17787	Neuronal acetylcholine receptor subunit beta-2	CHRN beta	C00028578	1 / 1
P11473	Vitamin D3 receptor	NR1I1	C00001653	2 / 3
O75496	Geminin	Unclassified protein	C00001632	0 / 0
P46098	5-hydroxytryptamine receptor 3A	NS	C00028578	0 / 0
P32297	Neuronal acetylcholine receptor subunit alpha-3	CHRN alpha	C00028578	1 / 0
P36544	Neuronal acetylcholine receptor subunit alpha-7	CHRN alpha	C00028578	0 / 0
P30926	Neuronal acetylcholine receptor subunit beta-4	CHRN beta	C00028578	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00028578	3 / 3
P23415	Glycine receptor subunit alpha-1	GLR alpha	C00028578	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00028578	2 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00001635	0 / 0
Q15822	Neuronal acetylcholine receptor subunit alpha-2	CHRN alpha	C00028578	1 / 1
Q8WXA8	5-hydroxytryptamine receptor 3C	NS	C00028578	0 / 0
Q70Z44	5-hydroxytryptamine receptor 3D	NS	C00028578	0 / 0
O95264	5-hydroxytryptamine receptor 3B	NS	C00028578	0 / 0
A5X5Y0	5-hydroxytryptamine receptor 3E	NS	C00028578	0 / 0
Q9UGM1	Neuronal acetylcholine receptor subunit alpha-9	CHRN alpha	C00028578	0 / 0
Q9GZZ6	Neuronal acetylcholine receptor subunit alpha-10	CHRN alpha	C00028578	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00001653	1 / 1

15 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00028578
627	BDNF, ANON2, BULN2	brain-derived neurotrophic factor	C00028578
1137	CHRNA4, BFNC, EBN, EBN1, NACHR, NACHRA4, NACRA4	cholinergic receptor, nicotinic, alpha 4 (neuronal)	C00028578
1139	CHRNA7, CHRNA7-2, NACHRA7	cholinergic receptor, nicotinic, alpha 7 (neuronal)	C00028578
1141	CHRNB2, EFNL3, nAChRB2	cholinergic receptor, nicotinic, beta 2 (neuronal)	C00028578
1621	DBH, DBM	dopamine beta-hydroxylase (dopamine beta-monooxygenase) (EC:1.14.17.1)	C00028578
3674	ITGA2B, BDPLT16, BDPLT2, CD41, CD41B, GP2B, GPIIb, GT, GTA, HPA3	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)	C00028578
3690	ITGB3, BDPLT16, BDPLT2, CD61, GP3A, GPIIIa, GT	integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)	C00028578
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00028578
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00028578
4915	NTRK2, GP145-TrkB, TRKB, trk-B	neurotrophic tyrosine kinase, receptor, type 2 (EC:2.7.10.1)	C00028578
6774	STAT3, APRF, HIES	signal transducer and activator of transcription 3 (acute-phase response factor)	C00028578
7054	TH, DYT14, DYT5b, TYH	tyrosine hydroxylase (EC:1.14.16.2)	C00028578
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00028578
7538	ZFP36, G0S24, GOS24, NUP475, RNF162A, TIS11, TTP, zfp-36	ZFP36 ring finger protein	C00028578

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions