Centaurea armena
Species
KNApSAcK Entry
| Organism name | Centaurea armena |
|---|---|
| Genus | Centaurea |
| Family | Asteraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Centaurea armena |
|---|---|
| Linked NCBI taxonomy ID | 363414 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (18)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003118
|
Copaene
/ alpha-Copaene / (-)-alpha-Copaene |
No. 333 | No. 38 |
|
||||
|
C00003110
|
Caryophyllene
/ (E)-Caryophyllene / beta-Caryophyllene / (-)-(E)-Caryophyllene / (E)-beta-Caryophyllene |
CHEMBL445740
CHEMBL448700 |
2 / 3 / 7 | No. 478 | No. 38 |
|
||
|
C00000164
|
beta-Eudesmol
|
CHEMBL88244
|
C051082
|
No. 524 | No. 38 |
|
||
|
C00032309
|
Tetradecanol
/ 1-Tetradecanol |
CHEMBL24022
|
C020940
|
1 / 0 / 0 | No. 599 |
|
||
|
C00035560
|
Cetene
|
C010734
|
No. 599 |
|
||||
|
C00030480
|
Hexahydrofarnesyl acetone
/ 6,10,14-Trimethyl-2-pentadecanone |
C014584
|
No. 641 | No. 38 |
|
|||
|
C00022119
|
(Z)-Phytol
/ cis-Phytol |
CHEMBL390773
CHEMBL1644111 |
No. 641 | No. 38 |
|
|||
|
C00022075
|
Neophytadiene
|
No. 641 | No. 38 |
|
||||
|
C00007242
|
beta-Bisabolene
/ l-beta-Bisabolene / (-)-beta-Bisabolene |
CHEMBL444389
CHEMBL1077088 CHEMBL2001434 |
No. 701 | No. 38 |
|
|||
|
C00035438
|
(E)-2-Tetradecen-1-ol
|
No. 877 |
|
|||||
|
C00007535
|
Phenylacetaldehyde
/ Benzeneacetaldehyde / Phenylacetic aldehyde |
C013192
|
3 / 0 | No. 885 |
|
|||
|
C00029881
|
Calarene
/ (+)-1(10)-Aristolene |
No. 1097 |
|
|||||
|
C00022163
|
Farnesylacetone
/ Farnesyl acetone |
CHEMBL486207
|
No. 1468 |
|
||||
|
C00000149
|
Spathulenol
|
CHEMBL518542
CHEMBL1774433 |
C013258
|
No. 1603 |
|
|||
|
C00035563
|
cis-Geranyl acetone
|
No. 2572 |
|
|||||
|
C00011720
|
Germacrene D
/ (-)-Germacrene D |
CHEMBL105432
CHEMBL1836650 |
No. 2639 | No. 38 |
|
|||
|
C00034452
|
Benzaldehyde
|
CHEMBL15972
|
C032175
|
8 / 7 / 3 | 3 / 1 | No. 6311 |
|
|
|
C00035536
|
beta-Damascenone
|
No. 8050 |
|
Human Protein / Gene in interactions
11 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00034452 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00034452 | 0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00034452 | 0 / 0 |
| P14902 | Indoleamine 2,3-dioxygenase 1 | Enzyme | C00034452 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00034452 | 2 / 0 |
| P10145 | Interleukin-8 | Secreted protein | C00034452 | 0 / 0 |
| P14679 | Tyrosinase | Oxidoreductase | C00034452 | 4 / 2 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00032309 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00034452 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00003110 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003110 | 1 / 2 |
6 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1646 | AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8 | aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357) |
C00007535
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00007535
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00007535
|
| 217 | ALDH2, ALDH-E2, ALDHI, ALDM | aldehyde dehydrogenase 2 family (mitochondrial) (EC:1.2.1.3) |
C00034452
|
| 218 | ALDH3A1, ALDH3, ALDHIII | aldehyde dehydrogenase 3 family, member A1 (EC:1.2.1.5) |
C00034452
|
| 221 | ALDH3B1, ALDH4, ALDH7 | aldehyde dehydrogenase 3 family, member B1 (EC:1.2.1.5) |
C00034452
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (10)
| OMIM | preferred title | UniProt |
|---|---|---|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
KEGG DISEASE (10)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|