Species

KNApSAcK Entry

Organism name Consolida oliveriana DC Schrod
Genus Consolida
Family Ranunculaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Consolida
Linked NCBI taxonomy ID 37493
Linked level genus

Family

Family in NCBI taxonomy Ranunculaceae
ID 3440

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001634 External link 512 Delsoline
CHEMBL1242534
CHEMBL1474356
CHEMBL2112855
C045308
8 / 15 / 13 No. 31 No. 10
C00028885 External link 512 Pubescenine
No. 31 No. 10
C00028303 External link 512 Gigactonine
CHEMBL1242625
No. 31 No. 10
C00028084 External link 512 Consolidine
/ (+)-Consolidine
/ O-Deacetyl-14-O-methylpubescenine
No. 31 No. 10
C00027824 External link 512 Ajaconine
No. 274 No. 10

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001634 1 / 0
P02545 Prelamin-A/C Unclassified protein C00001634 11 / 10
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001634 0 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00001634 2 / 0
O75496 Geminin Unclassified protein C00001634 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001634 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001634 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001634 0 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (15)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545

KEGG DISEASE (13)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)