Species

KNApSAcK Entry

Organism name Delphinium crispulum
Genus Delphinium
Family Ranunculaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Delphinium crispulum
Linked NCBI taxonomy ID 1127152
Linked level species

Family

Family in NCBI taxonomy Ranunculaceae
ID 3440

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001649 External link 512 Karakoline
CHEMBL1242438
CHEMBL1496845
CHEMBL1513445
CHEMBL1514236
CHEMBL1525359
CHEMBL1872961
8 / 14 / 15 No. 31 No. 10
C00040956 External link 512 Ezochasmanine
CHEMBL2140549
1 / 0 / 0 No. 31 No. 10
C00028417 External link 512 Isotalatizidine
CHEMBL1242437
C423465
No. 31 No. 10
C00040928 External link 512 Crispulidine
No. 31 No. 10
C00031729 External link 512 Deltatsine
No. 31 No. 10
C00028344 External link 512 Hetisine
/ Delatine
CHEMBL1315226
1 / 0 / 0 No. 121 No. 10
C00040936 External link 512 Delphicrispuline
No. 475 No. 10

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001649 1 / 0
P02545 Prelamin-A/C Unclassified protein C00001649 11 / 10
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001649 0 / 1
P54132 Bloom syndrome protein Enzyme C00001649 1 / 2
O75496 Geminin Unclassified protein C00040956 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001649 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001649 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001649 0 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00028344 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00001649 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#210900 Bloom syndrome; blm P54132
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545

KEGG DISEASE (15)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)