Species

KNApSAcK Entry

Organism name Tabernaemontana calcarea Pichon
Genus Tabernaemontana
Family Apocynaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Tabernaemontana calcarea
Linked NCBI taxonomy ID 761054
Linked level species

Family

Family in NCBI taxonomy Apocynaceae
ID 4056

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (7)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00025416 External link 512 Pandoline
/ (+)-Pandoline
/ (+)-7alpha-Hydroxy pseudovincadifformine
No. 61 No. 4
C00025410 External link 512 Epipandoline
/ 7-Epipandoline
/ 20-Epipandoline
/ 20-epi-Pandoline
/ (+)-20-Epipandoline
No. 61 No. 4
C00025415 External link 512 Pandine
/ (+)-Pandine
No. 61 No. 4
C00026032 External link 512 Silicine
/ Decarbomethoxy-20-epiervatamine
/ 16-Decarbomethoxy-20-epiervatamine
/ 16-Demethoxycarbonyl-20-epiervatamine
No. 1428
C00001689 External link 512 Apparicine
/ (-)-Apparicine
CHEMBL285671
1 / 0 / 1 No. 1476
C00025695 External link 512 (20R)-Pseudovincadifformine
No. 1673
C00025859 External link 512 Dregamine
/ (-)-Dregamine
/ 20-Epitabernemontanine
CHEMBL564301
CHEMBL1480853
CHEMBL1594801
CHEMBL1967575
CHEMBL2006905
9 / 2 / 3 No. 1771

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00025859 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00025859 0 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00025859 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00025859 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00025859 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00001689 0 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00025859 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00025859 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00025859 0 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00025859 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635

KEGG DISEASE (4)

KEGG name UniProt
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)