| Organism name | Tabernaemontana orientalis R.Br. |
|---|---|
| Genus | Tabernaemontana |
| Family | Apocynaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Tabernaemontana orientalis |
|---|---|
| Linked NCBI taxonomy ID | 715769 |
| Linked level | species |
| Family in NCBI taxonomy | Apocynaceae |
|---|---|
| ID | 4056 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00025415
|
Pandine
/ (+)-Pandine |
No. 61 | No. 4 |
|
||||
|
C00025416
|
Pandoline
/ (+)-Pandoline / (+)-7alpha-Hydroxy pseudovincadifformine |
No. 61 | No. 4 |
|
||||
|
C00025410
|
Epipandoline
/ 7-Epipandoline / 20-Epipandoline / 20-epi-Pandoline / (+)-20-Epipandoline |
No. 61 | No. 4 |
|
||||
|
C00025227
|
Voacristine
/ (-)-Voacristine / (-)-Voacangarine |
CHEMBL463317
CHEMBL512646 |
C049505
|
No. 250 | No. 4 |
|
||
|
C00025916
|
Isovoacangine
/ (-)-Isovoacangine |
CHEMBL360427
CHEMBL1713663 |
5 / 3 / 1 | No. 250 | No. 4 |
|
||
|
C00025223
|
Voacangine
/ (-)-Voacangine / Carbomethoxyibogaine |
CHEMBL182120
|
C012098
|
No. 250 | No. 4 |
|
||
|
C00025824
|
Conopharyngine
|
CHEMBL523582
|
C007113
|
No. 250 | No. 4 |
|
||
|
C00001689
|
Apparicine
/ (-)-Apparicine |
CHEMBL285671
|
1 / 0 / 1 | No. 1476 |
|
|||
|
C00025734
|
20-Epiervatamine
|
CHEMBL2133481
|
1 / 0 / 0 | No. 1771 |
|
|||
|
C00025866
|
Ervatamine
|
CHEMBL2133481
|
C017291
|
1 / 0 / 0 | No. 1771 |
|
||
|
C00025859
|
Dregamine
/ (-)-Dregamine / 20-Epitabernemontanine |
CHEMBL564301
CHEMBL1480853 CHEMBL1594801 CHEMBL1967575 CHEMBL2006905 |
9 / 2 / 3 | No. 1771 |
|
|||
|
C00026055
|
20-Epidregamine
/ Tabernaemontanin / Tabernaemontanine / (-)-Tabernemontanine / (-)-Tabernaemontanine |
CHEMBL564301
CHEMBL1480853 CHEMBL1594801 CHEMBL1967575 CHEMBL2006905 |
9 / 2 / 3 | No. 1771 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| O75496 | Geminin | Unclassified protein | C00025734 C00025866 C00025916 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00025859 C00026055 | 1 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00025859 C00026055 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00025859 C00026055 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00025859 C00026055 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00025859 C00026055 | 0 / 1 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00025859 C00026055 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00025859 C00026055 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00025859 C00026055 | 1 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00025859 C00026055 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00025916 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00001689 | 0 / 1 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00025916 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00025916 | 2 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00025916 | 1 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| KEGG | name | UniProt |
|---|---|---|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|