PCIDB

Ervatamia divaricata Gouyahua

Species

KNApSAcK Entry

Organism name Ervatamia divaricata Gouyahua
Genus Ervatamia
Family Apocynaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Apocynaceae
Linked NCBI taxonomy ID 4056
Linked level family

Family

Family in NCBI taxonomy Apocynaceae
ID 4056

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (13)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00025216 External link 512 Tubotaiwine
/ Methyl (14beta)-2,16-didehydrocondyfolan-16-carboxylate
CHEMBL508920
C404563
No. 61 No. 4
C00001773 External link 512 Tabersonine
CHEMBL1971886
CHEMBL2011511
C009373
No. 61 No. 4
C00025698 External link 512 19,20-Dihydrotabernamine
/ (20'S)-19',20'-Dihydrotabernamine
No. 217
C00001709 External link 512 Coronaridine
/ (-)-Coronaridine
CHEMBL364613
CHEMBL1740280
C011734
No. 250 No. 4
C00025223 External link 512 Voacangine
/ (-)-Voacangine
/ Carbomethoxyibogaine
CHEMBL182120
C012098
No. 250 No. 4
C00024619 External link 512 Voaphyllin
/ Conoflorin
/ Conoflorine
/ Voaphylline
/ (+)-Conoflorine
/ (+)-Voaphylline
CHEMBL496674
No. 828
C00039952 External link 512 Pericalline
CHEMBL285671
C008811
1 / 0 / 1 No. 1476
C00025224 External link 512 Voacangine hydroxyindolenine
/ 7alpha-Hydroxyvoacangine indolenine
CHEMBL488201
No. 1560
C00025159 External link 512 Coronaridine hydroxyindolenine
CHEMBL184480
No. 1560
C00025734 External link 512 20-Epiervatamine
CHEMBL2133481
1 / 0 / 0 No. 1771
C00025859 External link 512 Dregamine
/ (-)-Dregamine
/ 20-Epitabernemontanine
CHEMBL564301
CHEMBL1480853
CHEMBL1594801
CHEMBL1967575
CHEMBL2006905
9 / 2 / 3 No. 1771
C00026055 External link 512 20-Epidregamine
/ Tabernaemontanin
/ Tabernaemontanine
/ (-)-Tabernemontanine
/ (-)-Tabernaemontanine
CHEMBL564301
CHEMBL1480853
CHEMBL1594801
CHEMBL1967575
CHEMBL2006905
9 / 2 / 3 No. 1771
C00001742 External link 512 Ibogamine
CHEMBL467828
No. 2446 No. 4

Human Protein / Gene in interactions

11 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00025859 C00026055 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00025859 C00026055 0 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00025859 C00026055 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00025859 C00026055 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00025859 C00026055 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00025859 C00026055 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00025859 C00026055 0 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00025859 C00026055 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00025859 C00026055 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00039952 0 / 1
O75496 Geminin Unclassified protein C00025734 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635

KEGG DISEASE (4)

KEGG name UniProt
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)