Species

KNApSAcK Entry

Organism name Claviceps sp. SD58
Genus Claviceps
Family Clavicipitaceae
Kingdom Fungi

NCBI taxonomy

Entry

Linked NCBI taxonomy name Claviceps
Linked NCBI taxonomy ID 5110
Linked level genus

Family

Family in NCBI taxonomy Clavicipitaceae
ID 34397

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Fungi
ID 4751

Plant class

Plant class
ID

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00001717 External link 512 Elymoclavine
CHEMBL1356713
C007586
9 / 12 / 17 0 / 2 No. 987 No. 4
C00011214 External link 512 Norchanoclavine II
/ N-Demethylchanoclavine-II
C007244
No. 987 No. 4
C00011210 External link 512 Elymoclavine-O-beta-fructofuranoside
No. 4796
C00011211 External link 512 Elymoclavine-O-beta-fructofuranosyl-(2->1)-O-beta-D-ructofuranoside
No. 4796

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P11473 Vitamin D3 receptor NR1I1 C00001717 2 / 3
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00001717 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00001717 3 / 3
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001717 0 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00001717 4 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00001717 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00001717 0 / 0
O00255 Menin Unclassified protein C00001717 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001717 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (17)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D002375 Catalepsy C00001717
D012640 Seizures C00001717