PCIDB

Stephania hernandifolia

Species

KNApSAcK Entry

Organism name Stephania hernandifolia
Genus Stephania
Family Menispermaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Stephania hernandifolia
Linked NCBI taxonomy ID 152366
Linked level species

Family

Family in NCBI taxonomy Menispermaceae
ID 3455

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00025760 External link 512 Frangchinoline
/ 7-O-Demethyltetrandrine
CHEMBL504256
CHEMBL509803
CHEMBL500614
12 / 6 / 3 No. 10 No. 4
C00001866 External link 512 Hernandezine
CHEMBL504936
C067193
5 / 4 / 8 No. 10 No. 4
C00001793 External link 512 Aknadicine
CHEMBL2000216
No. 559 No. 4

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00025760 1 / 1
P10253 Lysosomal alpha-glucosidase Hydrolase C00025760 1 / 1
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00025760 0 / 1
P08183 Multidrug resistance protein 1 drug C00025760 1 / 0
P11473 Vitamin D3 receptor NR1I1 C00001866 2 / 3
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00025760 0 / 0
P39748 Flap endonuclease 1 Enzyme C00025760 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00025760 2 / 0
O75496 Geminin Unclassified protein C00025760 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00025760 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00025760 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00001866 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00001866 1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00025760 1 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00025760 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00001866 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00001866 1 / 4

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#114500 Colorectal cancer; crc P84022
#137800 Glioma susceptibility 1; glm1 O75874
#232300 Glycogen storage disease ii P10253
#612244 Inflammatory bowel disease 13; ibd13 P08183
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (10)

KEGG name UniProt
H00079 Asthma P07550 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)