Stephania sasakii

• Index
• Plant Species
• Metabolite list (2)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Stephania sasakii
Genus	Stephania
Family	Menispermaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Stephania
Linked NCBI taxonomy ID	147243
Linked level	genus

Family

Family in NCBI taxonomy	Menispermaceae
ID	3455

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	eudicotyledons
ID	71240

Metabolite list (2)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00001817	Berbamine / d-Berbamine / (+)-Berbamine	CHEMBL504323 CHEMBL507540 CHEMBL1198334	C027870	4 / 3 / 4	9 / 1	No. 10	No. 4
C00001836	Cepharanthine	CHEMBL472588 CHEMBL449782 CHEMBL475273 CHEMBL1473842	C006947	22 / 19 / 17	1 / 1	No. 10	No. 4

Human Protein / Gene in interactions

24 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00001817 C00001836	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00001817 C00001836	0 / 1
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00001817	3 / 3
P54750	Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	PDE_1A	C00001817	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00001836	1 / 1
P39748	Flap endonuclease 1	Enzyme	C00001836	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00001836	2 / 0
O75496	Geminin	Unclassified protein	C00001836	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00001836	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00001836	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00001836	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00001836	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00001836	0 / 0
O15118	Niemann-Pick C1 protein	Unclassified protein	C00001836	1 / 1
P04062	Glucosylceramidase	Enzyme	C00001836	6 / 4
O75164	Lysine-specific demethylase 4A	Enzyme	C00001836	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00001836	4 / 3
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00001836	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00001836	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00001836	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00001836	1 / 1
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00001836	1 / 0
O00255	Menin	Unclassified protein	C00001836	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00001836	1 / 2

10 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
5243	ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1	ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44)	C00001836
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00001817
637	BID, FP497	BH3 interacting domain death agonist	C00001817
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00001817
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00001817
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00001817
1147	CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16	conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10)	C00001817
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00001817
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00001817
7128	TNFAIP3, A20, OTUD7C, TNFA1P2	tumor necrosis factor, alpha-induced protein 3 (EC:3.4.19.12)	C00001817

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions