PCIDB

Tithonia rotundifolia

Species

KNApSAcK Entry

Organism name Tithonia rotundifolia
Genus Tithonia
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Tithonia rotundifolia
Linked NCBI taxonomy ID 105388
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (14)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00011780 External link 512 Mollisorin A
No. 60 No. 38
C00000169 External link 512 1beta,10alpha-Epoxy-8beta-hydroxy-14-acetoxy-4E,11(13)-germacradien-12,6-olide
No. 94 No. 38
C00000168 External link 512 1beta,10alpha-Epoxy-8beta,14-dihydroxy-4E,11(13)-germacradien-12,6-olide
No. 94 No. 38
C00012138 External link 512 Rotundin
No. 94 No. 38
C00012976 External link 512 Tirotundifolin C
/ (+)-Tirotundifolin C
/ (3aR,4R,5aR,6R,9aS,9bR)-[partial]- 2,3,3a,4,5,5a,6,7,9a,9b-Decahydro-6-hydroxy-5a,9-dimethyl-3-methylene-2-oxonaphtho[1,2-b]furan-4-yl ester 3-hydroxy-2-methylenebutanoic acid
CHEMBL411470
No. 214 No. 38
C00012977 External link 512 Tirotundifolin D
/ [3aR-[3aalpha,4beta(Z),5abeta,6beta,9aalpha,9bbeta]]-2,3,3a,4,5,5a,6,7,9a,9b-decahydro-6-hydroxy-5a,9-dimethyl-3-methylene-2-oxonaphtho[1,2-b]furan-4-yl ester 2-(hydroxymethyl)-2-butenoic acid
No. 214 No. 38
C00013234 External link 512 Tirotundifolin B
/ (-)-Tirotundifolin B
/ (3aR,4R,5aR,6R,9bS)-[partial]-2,3,3a,4,5,5a,6,7,8,9b-Decahydro-6-hydroxy-5a,9-dimethyl-3-methylene-2-oxonaphtho[1,2-b]furan-4-yl ester 3-hydroxy-2-methylenebutanoic acid
No. 214 No. 38
C00012145 External link 512 Tithonin
No. 687 No. 38
C00012146 External link 512 3-O-Methyltithonin
No. 687 No. 38
C00012151 External link 512 Argophyllin A
No. 1051
C00012985 External link 512 Tirotundifolin E
/ (+)-Tirotundifolin E
/ Dodecahydro-6-hydroxy-5a,9-dimethyl-3-methylene-2-oxonaphtho[1,2-b]furan-4-yl ester 2,3-dihydroxy-2-methylbutanoic acid
No. 1128
C00011888 External link 512 [3aS-(3aR*,4S*,6R*,9S*,10R*,11aS*)]-9-Ethoxydodecahydro-6,10-dimethyl-3-methylene-2-oxo-6,9-epoxycyclodeca[b]furan-4-yl ester 2-methyl-propanoic acid
No. 2080
C00011887 External link 512 Tirotundin
/ Tagitinin D
CHEMBL464453
3 / 5 / 3 No. 2080
C00012984 External link 512 Tirotundifolin A
/ (+)-Tirotundifolin A
CHEMBL272870
No. 3535

Human Protein / Gene in interactions

3 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q04206 Transcription factor p65 Transcription Factor C00011887 0 / 0
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00011887 5 / 3
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00011887 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#137800 Glioma susceptibility 1; glm1 P37231
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#601665 Obesity P37231

KEGG DISEASE (3)

KEGG name UniProt
H00032 Thyroid cancer P37231 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)