Heliotropium europaeum
Species
KNApSAcK Entry
| Organism name | Heliotropium europaeum |
|---|---|
| Genus | Heliotropium |
| Family | Boraginaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Heliotropium europaeum |
|---|---|
| Linked NCBI taxonomy ID | 168345 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Boraginaceae |
|---|---|
| ID | 21571 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Natural Activity
List (6)
| Species | Activity |
|---|---|
| Heliotropium europaeum L. | Antipyretic |
| Heliotropium europaeum L. | Carcinogenic |
| Heliotropium europaeum L. | Cholagogue |
| Heliotropium europaeum L. | Emmenagogue |
| Heliotropium europaeum L. | Hepatotoxic |
| Heliotropium europaeum L. | Poison |
Metabolite list (7)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00002086
|
Europine
|
CHEMBL526357
CHEMBL1964449 |
No. 308 | No. 2 |
|
|||
|
C00002090
|
Heliotrine
|
CHEMBL1474445
CHEMBL1978598 CHEMBL2165593 |
C010178
|
6 / 3 / 4 | No. 308 | No. 2 |
|
|
|
C00002097
|
Lasiocarpine
|
CHEMBL498236
CHEMBL1999554 CHEMBL2138247 |
C005136
|
2 / 7 / 3 | No. 623 | No. 2 |
|
|
|
C00026180
|
Acetyllasiocarpine
/ Lasiocarpine monoacetate |
No. 623 | No. 2 |
|
||||
|
C00026201
|
Heliotrine oxide
/ Heliotrine N-oxide |
C020350
|
No. 1570 |
|
||||
|
C00026181
|
Acetyllasiocarpine N-oxide
/ 4'-Acetyllasiocarpine N-oxide |
No. 3366 |
|
|||||
|
C00026210
|
Lasiocarpine oxide
/ Lasiocarpine N-oxide / Lasiocarpine, 4-oxide |
No. 3366 |
|
Human Protein / Gene in interactions
8 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002090 | 1 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00002090 | 1 / 1 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00002090 | 0 / 1 |
| O75496 | Geminin | Unclassified protein | C00002097 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00002097 | 7 / 3 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00002090 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002090 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002090 | 0 / 1 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (10)
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
KEGG DISEASE (7)
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|