Veratrum californicum
Species
KNApSAcK Entry
| Organism name | Veratrum californicum |
|---|---|
| Genus | Veratrum |
| Family | Melanthiaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Veratrum californicum |
|---|---|
| Linked NCBI taxonomy ID | 50242 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Melanthiaceae |
|---|---|
| ID | 50362 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Liliopsida |
|---|---|
| ID | 4447 |
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00002245
|
Cyclopamine
|
CHEMBL254129
CHEMBL1590308 CHEMBL2132004 |
C000541
|
7 / 9 / 14 | 0 / 8 | No. 1844 | No. 11 |
|
Human Protein / Gene in interactions
7 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q15465 | Sonic hedgehog protein | Unclassified protein | C00002245 | 4 / 5 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00002245 | 2 / 3 |
| P08151 | Zinc finger protein GLI1 | Unclassified protein | C00002245 | 0 / 0 |
| P30518 | Vasopressin V2 receptor | Vasopressin and oxytocin receptor | C00002245 | 2 / 2 |
| Q99835 | Smoothened homolog | Smoothened receptor (frizzled family GPCR) | C00002245 | 0 / 1 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00002245 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00002245 | 1 / 4 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (9)
| OMIM | preferred title | UniProt |
|---|---|---|
| #304800 | Diabetes insipidus, nephrogenic, x-linked |
P30518
|
| #142945 | Holoprosencephaly 3; hpe3 |
Q15465
|
| #611638 | Microphthalmia, isolated, with coloboma 5; mcopcb5 |
Q15465
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #300539 | Nephrogenic syndrome of inappropriate antidiuresis; nsiad |
P30518
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #174500 | Polydactyly, preaxial ii; ppd2 |
Q15465
|
| #147250 | Solitary median maxillary central incisor; smmci |
Q15465
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (14)
| KEGG | name | UniProt |
|---|---|---|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00252 | Congenital nephrogenic diabetes insipidus (NDI) |
P30518
(related)
|
| H01294 | Nephrogenic syndrome of inappropriate antidiuresis (NSIAD) |
P30518
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00039 | Basal cell carcinoma |
Q15465
(related)
Q99835 (related) |
| H00267 | Holoprosencephaly (HPE) |
Q15465
(related)
|
| H00652 | Solitary median maxillary central incisor syndrome |
Q15465
(related)
|
| H01027 | Anophthalmia and microphthalmia (A/M) |
Q15465
(related)
|
| H01160 | Schizencephaly |
Q15465
(related)
|
Diseases related to CTD interactions
8 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D000014 | Abnormalities, Drug-Induced |
C00002245
|
| D002971 | Cleft Lip |
C00002245
|
| D002972 | Cleft Palate |
C00002245
|
| D019465 | Craniofacial Abnormalities |
C00002245
|
| D004487 | Edema |
C00002245
|
| D016142 | Holoprosencephaly |
C00002245
|
| D007569 | Jaw Abnormalities |
C00002245
|
| D049188 | Prenatal Injuries |
C00002245
|