Species

KNApSAcK Entry

Organism name Solanum demissum
Genus Solanum
Family Solanaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Solanum demissum
Linked NCBI taxonomy ID 50514
Linked level species

Family

Family in NCBI taxonomy Solanaceae
ID 4070

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002248 External link 512 Demissine
No. 21 No. 11
C00002267 External link 512 Tomatidine
CHEMBL365417
CHEMBL1476096
CHEMBL1622974
CHEMBL1976775
CHEMBL1998601
CHEMBL2165711
C003677
10 / 15 / 14 No. 171 No. 11
C00000218 External link 512 Jasmonic acid
/ trans-Jasmonic acid
/ 3-Oxo-2-(2Z-pentenyl)cyclotentylacetic acid
CHEMBL445499
CHEMBL449572
C011006
4 / 1 / 0 No. 707 No. 70
C00000220 External link 512 11-Hydroxyjasmonic acid
No. 707 No. 70
C00000233 External link 512 12-Hydroxyjasmonic acid
No. 707 No. 70
C00028163 External link 512 Demissidine
/ Dihydrosolanidine
CHEMBL2165408
C015108
No. 1197 No. 11
C00013243 External link 512 Rishitinol
/ (2R,3S)-rel-(+)-1,2,3,4-Tetrahydro-3-hydroxy-alpha,alpha,5,8-tetramethyl-2-naphthalenemethanol
No. 2030
C00003178 External link 512 Rishitin
No. 6390 No. 38

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase Enzyme C00002267 1 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002267 1 / 0
P17516 Aldo-keto reductase family 1 member C4 Enzyme C00000218 1 / 0
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00002267 0 / 0
P02545 Prelamin-A/C Unclassified protein C00002267 11 / 10
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002267 0 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00002267 0 / 0
P42330 Aldo-keto reductase family 1 member C3 Enzyme C00000218 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00002267 1 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002267 0 / 0
Q04828 Aldo-keto reductase family 1 member C1 Enzyme C00000218 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002267 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002267 0 / 1
P52895 Aldo-keto reductase family 1 member C2 Enzyme C00000218 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (16)

OMIM preferred title UniProt
#614279 46,xy sex reversal 8; srxy8 P17516
P52895
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#302960 Chondrodysplasia punctata 2, x-linked dominant; cdpx2 Q15125
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545

KEGG DISEASE (14)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H01194 X-linked chondrodysplasia punctata Q15125 (related)