Species

KNApSAcK Entry

Organism name Solanum khasianum
Genus Solanum
Family Solanaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Solanum aculeatissimum
Linked NCBI taxonomy ID 267265
Linked level species

Family

Family in NCBI taxonomy Solanaceae
ID 4070

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002260 External link 512 Solamargine
CHEMBL443114
CHEMBL2005327
No. 17 No. 11
C00049399 External link 512 Solakhasoside
/ (-)-Solakhasoside
No. 17 No. 11
C00002265 External link 512 Solasonine
CHEMBL438956
CHEMBL1967295
No. 17 No. 11
C00002264 External link 512 Solasodine
CHEMBL372484
CHEMBL518252
CHEMBL514596
CHEMBL1485302
CHEMBL1515688
CHEMBL1741560
CHEMBL1964743
C012037
12 / 14 / 46 No. 171 No. 11

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q15125 3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase Enzyme C00002264 1 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002264 1 / 0
P04637 Cellular tumor antigen p53 Transcription Factor C00002264 7 / 37
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002264 0 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00002264 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00002264 1 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00002264 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002264 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002264 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002264 0 / 1
O00255 Menin Unclassified protein C00002264 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00002264 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#302960 Chondrodysplasia punctata 2, x-linked dominant; cdpx2 Q15125
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#133239 Esophageal cancer P04637
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#211980 Lung cancer P04637
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#260500 Papilloma of choroid plexus; cpp P04637
#275355 Squamous cell carcinoma, head and neck; hnscc P04637

KEGG DISEASE (46)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
P04637 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H01194 X-linked chondrodysplasia punctata Q15125 (related)