Species

KNApSAcK Entry

Organism name Gliocladium fimbriatum
Genus Gliocladium
Family Hypocreaceae
Kingdom Fungi

NCBI taxonomy

Entry

Linked NCBI taxonomy name Gliocladium
Linked NCBI taxonomy ID 62887
Linked level genus

Family

Family in NCBI taxonomy
ID

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Fungi
ID 4751

Plant class

Plant class
ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002340 External link 512 Gliotoxin
CHEMBL331627
CHEMBL1972524
D005912
8 / 2 / 3 7 / 1 No. 5539

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O43463 Histone-lysine N-methyltransferase SUV39H1 Enzyme C00002340 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00002340 2 / 3
Q8WTS6 Histone-lysine N-methyltransferase SETD7 Enzyme C00002340 0 / 0
P06732 Creatine kinase M-type Enzyme C00002340 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00002340 0 / 0
P49356 Protein farnesyltransferase subunit beta Enzyme C00002340 0 / 0
P49354 Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha Enzyme C00002340 0 / 0
P53609 Geranylgeranyl transferase type-1 subunit beta Enzyme C00002340 0 / 0

7 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
330 BIRC3, AIP1, API2, CIAP2, HAIP1, HIAP1, MALT2, MIHC, RNF49, c-IAP2 baculoviral IAP repeat containing 3 C00002340
3458 IFNG, IFG, IFI interferon, gamma C00002340
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00002340
4790 NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 C00002340
5970 RELA, NFKB3, p65 v-rel avian reticuloendotheliosis viral oncogene homolog A C00002340
6648 SOD2, IPOB, MNSOD, MVCD6 superoxide dismutase 2, mitochondrial (EC:1.15.1.1) C00002340
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00002340

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (3)

KEGG name UniProt
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D056486 Drug-Induced Liver Injury C00002340