Tylophora asthmatica
Species
KNApSAcK Entry
| Organism name | Tylophora asthmatica |
|---|---|
| Genus | Tylophora |
| Family | Apocynaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Tylophora asthmatica |
|---|---|
| Linked NCBI taxonomy ID | 1266040 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Apocynaceae |
|---|---|
| ID | 4056 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00002367
|
Tylophorine
|
CHEMBL250426
CHEMBL258137 CHEMBL493620 |
C004218
|
18 / 0 | No. 410 |
|
Human Protein / Gene in interactions
18 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00002367
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00002367
|
| 890 | CCNA2, CCN1, CCNA | cyclin A2 |
C00002367
|
| 891 | CCNB1, CCNB | cyclin B1 |
C00002367
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00002367
|
| 993 | CDC25A, CDC25A2 | cell division cycle 25A (EC:3.1.3.48) |
C00002367
|
| 8837 | CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS | CASP8 and FADD-like apoptosis regulator |
C00002367
|
| 1147 | CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 | conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) |
C00002367
|
| 3654 | IRAK1, IRAK, pelle | interleukin-1 receptor-associated kinase 1 (EC:2.7.11.1) |
C00002367
|
| 9020 | MAP3K14, FTDCR1B, HS, HSNIK, NIK | mitogen-activated protein kinase kinase kinase 14 (EC:2.7.11.25) |
C00002367
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00002367
|
| 5293 | PIK3CD, P110DELTA, PI3K, p110D | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta (EC:2.7.1.153) |
C00002367
|
| 5530 | PPP3CA, CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B | protein phosphatase 3, catalytic subunit, alpha isozyme (EC:3.1.3.16) |
C00002367
|
| 5566 | PRKACA, PKACA | protein kinase, cAMP-dependent, catalytic, alpha (EC:2.7.11.11) |
C00002367
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00002367
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00002367
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00002367
|
| 8795 | TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 | tumor necrosis factor receptor superfamily, member 10b |
C00002367
|