Tylophora tanakae

• Index
• Plant Species
• Metabolite list (2)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Tylophora tanakae
Genus	Tylophora
Family	Apocynaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Tylophora tanakae
Linked NCBI taxonomy ID	228715
Linked level	species

Family

Family in NCBI taxonomy	Apocynaceae
ID	4056

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (2)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00002367	Tylophorine	CHEMBL250426 CHEMBL258137 CHEMBL493620	C004218		18 / 0	No. 410
C00032853	Conduritol F	CHEMBL19682 CHEMBL308805 CHEMBL74790 CHEMBL73813 CHEMBL307042 CHEMBL75175 CHEMBL1950779		3 / 5 / 7		No. 3096

Human Protein / Gene in interactions

3 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P16278	Beta-galactosidase	Enzyme	C00032853	4 / 6
P06280	Alpha-galactosidase A	Enzyme	C00032853	1 / 1
O43451	Maltase-glucoamylase, intestinal	Hydrolase	C00032853	0 / 0

18 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00002367
598	BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS	BCL2-like 1	C00002367
890	CCNA2, CCN1, CCNA	cyclin A2	C00002367
891	CCNB1, CCNB	cyclin B1	C00002367
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00002367
993	CDC25A, CDC25A2	cell division cycle 25A (EC:3.1.3.48)	C00002367
8837	CFLAR, CASH, CASP8AP1, CLARP, Casper, FLAME, FLAME-1, FLAME1, FLIP, I-FLICE, MRIT, c-FLIP, c-FLIPL, c-FLIPR, c-FLIPS	CASP8 and FADD-like apoptosis regulator	C00002367
1147	CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16	conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10)	C00002367
3654	IRAK1, IRAK, pelle	interleukin-1 receptor-associated kinase 1 (EC:2.7.11.1)	C00002367
9020	MAP3K14, FTDCR1B, HS, HSNIK, NIK	mitogen-activated protein kinase kinase kinase 14 (EC:2.7.11.25)	C00002367
4792	NFKBIA, IKBA, MAD-3, NFKBI	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha	C00002367
5293	PIK3CD, P110DELTA, PI3K, p110D	phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta (EC:2.7.1.153)	C00002367
5530	PPP3CA, CALN, CALNA, CALNA1, CCN1, CNA1, PPP2B	protein phosphatase 3, catalytic subunit, alpha isozyme (EC:3.1.3.16)	C00002367
5566	PRKACA, PKACA	protein kinase, cAMP-dependent, catalytic, alpha (EC:2.7.11.11)	C00002367
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00002367
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00002367
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00002367
8795	TNFRSF10B, CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9	tumor necrosis factor receptor superfamily, member 10b	C00002367

Related Diseases

Diseases related to proteins in ChEMBL interactions