Cercis chinensis
Species
KNApSAcK Entry
| Organism name | Cercis chinensis |
|---|---|
| Genus | Cercis |
| Family | Fabaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Cercis chinensis |
|---|---|
| Linked NCBI taxonomy ID | 161750 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (5)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00002384
|
Malvin
/ Malvidin diglucoside / Malvidin 3,5-diglucoside |
CHEMBL2009656
|
No. 1 | No. 15 |
|
|||
|
C00006737
|
Malvidin 3-diglucoside
|
No. 1 | No. 15 |
|
||||
|
C00006722
|
Petunidin 3-glucoside
/ Petunidin 3-O-beta-D-glucopyranoside |
CHEMBL1784264
|
C455107
|
No. 2 | No. 15 |
|
||
|
C00006735
|
Oenin
/ Malvidin 3-O-beta-D-glucopyranoside |
CHEMBL403236
|
C458419
|
1 / 0 | No. 2 | No. 15 |
|
|
|
C00004565
|
Kaempferol
/ Nimbecetin / Rhamnolutein / Pelargidenolon / 5,7,4'-Trihydroxyflavonol / 3,5,7,4'-Tetrahydroxyflavone / 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one |
CHEMBL150
|
C006552
|
76 / 69 / 87 | 86 / 8 | No. 71 | No. 15 |
|
Human Protein / Gene in interactions
76 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00004565 | 1 / 0 |
| P14061 | Estradiol 17-beta-dehydrogenase 1 | Enzyme | C00004565 | 0 / 0 |
| P33527 | Multidrug resistance-associated protein 1 | drugs | C00004565 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00004565 | 7 / 37 |
| Q9NPH5 | NADPH oxidase 4 | Enzyme | C00004565 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00004565 | 1 / 1 |
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00004565 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00004565 | 0 / 3 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00004565 | 2 / 2 |
| P04062 | Glucosylceramidase | Enzyme | C00004565 | 6 / 4 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00004565 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00004565 | 11 / 10 |
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00004565 | 1 / 1 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00004565 | 0 / 0 |
| Q00534 | Cyclin-dependent kinase 6 | CMGC serine/threonine protein kinase family | C00004565 | 1 / 0 |
| P11309 | Serine/threonine-protein kinase pim-1 | Pim | C00004565 | 0 / 0 |
| P04798 | Cytochrome P450 1A1 | Cytochrome P450 1A1 | C00004565 | 0 / 0 |
| P08183 | Multidrug resistance protein 1 | drug | C00004565 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00004565 | 0 / 1 |
| Q00535 | Cyclin-dependent kinase 5 | Cdk5 | C00004565 | 0 / 0 |
| Q15078 | Cyclin-dependent kinase 5 activator 1 | REG serine/threonine protein kinase family | C00004565 | 0 / 0 |
| Q9GZU7 | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 | Enzyme | C00004565 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00004565 | 1 / 8 |
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00004565 | 0 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00004565 | 0 / 0 |
| Q9Y3R4 | Sialidase-2 | Enzyme | C00004565 | 0 / 0 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00004565 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00004565 | 0 / 0 |
| P36888 | Receptor-type tyrosine-protein kinase FLT3 | Pdgfr | C00004565 | 1 / 1 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00004565 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00004565 | 0 / 0 |
| P15121 | Aldose reductase | Enzyme | C00004565 | 0 / 0 |
| P27487 | Dipeptidyl peptidase 4 | S9B | C00004565 | 0 / 1 |
| Q12791 | Calcium-activated potassium channel subunit alpha-1 | KCNM, KCa1.x | C00004565 | 1 / 1 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00004565 | 1 / 1 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00004565 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00004565 | 0 / 1 |
| P14679 | Tyrosinase | Oxidoreductase | C00004565 | 4 / 2 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00004565 | 5 / 3 |
| Q16678 | Cytochrome P450 1B1 | Cytochrome P450 1B1 | C00004565 | 4 / 4 |
| P06276 | Cholinesterase | Hydrolase | C00004565 | 0 / 0 |
| P04745 | Alpha-amylase 1 | Enzyme | C00004565 | 0 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00004565 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00004565 | 0 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00004565 | 3 / 3 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00004565 | 2 / 0 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00004565 | 2 / 2 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00004565 | 0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00004565 | 1 / 1 |
| P22303 | Acetylcholinesterase | Hydrolase | C00004565 | 1 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00004565 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00004565 | 1 / 1 |
| P37059 | Estradiol 17-beta-dehydrogenase 2 | Enzyme | C00004565 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00004565 | 0 / 1 |
| P98170 | E3 ubiquitin-protein ligase XIAP | Other cytosolic protein | C00004565 | 1 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00004565 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00004565 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00004565 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00004565 | 4 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00004565 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00004565 | 3 / 4 |
| Q07869 | Peroxisome proliferator-activated receptor alpha | NR1C1 | C00004565 | 0 / 0 |
| Q04760 | Lactoylglutathione lyase | Enzyme | C00004565 | 0 / 0 |
| P35869 | Aryl hydrocarbon receptor | Transcription Factor | C00004565 | 0 / 0 |
| P48147 | Prolyl endopeptidase | S9A | C00004565 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00004565 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00004565 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00004565 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00004565 | 1 / 2 |
| O95067 | G2/mitotic-specific cyclin-B2 | Other cytosolic protein | C00004565 | 0 / 0 |
| P14635 | G2/mitotic-specific cyclin-B1 | Other cytosolic protein | C00004565 | 0 / 0 |
| P06493 | Cyclin-dependent kinase 1 | Cdc2 | C00004565 | 0 / 0 |
| Q8WWL7 | G2/mitotic-specific cyclin-B3 | Other cytosolic protein | C00004565 | 0 / 0 |
| P49840 | Glycogen synthase kinase-3 alpha | Gsk | C00004565 | 0 / 0 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00004565 | 0 / 0 |
| Q9H0H5 | Rac GTPase-activating protein 1 | Unclassified protein | C00004565 | 0 / 0 |
87 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00004565
|
| 4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00004565
|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00004565
|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) |
C00004565
|
| 239 | ALOX12, 12-LOX, 12S-LOX, LOG12 | arachidonate 12-lipoxygenase (EC:1.13.11.31) |
C00004565
|
| 405 | ARNT, HIF-1-beta, HIF-1beta, HIF1-beta, HIF1B, HIF1BETA, TANGO, bHLHe2 | aryl hydrocarbon receptor nuclear translocator |
C00004565
|
| 472 | ATM, AT1, ATA, ATC, ATD, ATDC, ATE, TEL1, TELO1 | ataxia telangiectasia mutated (EC:2.7.11.1) |
C00004565
|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00004565
|
| 27113 | BBC3, JFY-1, JFY1, PUMA | BCL2 binding component 3 |
C00004565
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00004565
|
| 598 | BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS | BCL2-like 1 |
C00004565
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00004565
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00004565
|
| 6352 | CCL5, D17S136E, RANTES, SCYA5, SIS-delta, SISd, TCP228, eoCP | chemokine (C-C motif) ligand 5 |
C00004565
|
| 891 | CCNB1, CCNB | cyclin B1 |
C00004565
|
| 983 | CDK1, CDC2, CDC28A, P34CDC2 | cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) |
C00004565
|
| 1026 | CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
C00004565
|
| 1031 | CDKN2C, INK4C, p18, p18-INK4C | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) |
C00004565
|
| 1080 | CFTR, ABC35, ABCC7, CF, CFTR/MRP, MRP7, TNR-CFTR, dJ760C5.1 | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) (EC:3.6.3.49) |
C00004565
|
| 1147 | CHUK, IKBKA, IKK-alpha, IKK1, IKKA, NFKBIKA, TCF16 | conserved helix-loop-helix ubiquitous kinase (EC:2.7.11.10) |
C00004565
|
| 1401 | CRP, PTX1 | C-reactive protein, pentraxin-related |
C00004565
|
| 1437 | CSF2, GMCSF | colony stimulating factor 2 (granulocyte-macrophage) |
C00004565
|
| 37618 |
C00004565
|
||
| 54205 | CYCS, CYC, HCS, THC4 | cytochrome c, somatic |
C00004565
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00004565
|
| 1544 | CYP1A2, CP12, P3-450, P450(PA) | cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) |
C00004565
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00004565
|
| 1559 | CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 | cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) |
C00004565
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00004565
|
| 1734 | DIO2, 5DII, D2, DIOII, SelY, TXDI2 | deiodinase, iodothyronine, type II (EC:1.97.1.10) |
C00004565
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00004565
|
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00004565
|
| 2203 | FBP1, FBP | fructose-1,6-bisphosphatase 1 (EC:3.1.3.11) |
C00004565
|
| 2353 | FOS, AP-1, C-FOS, p55 | FBJ murine osteosarcoma viral oncogene homolog |
C00004565
|
| 4616 | GADD45B, GADD45BETA, MYD118 | growth arrest and DNA-damage-inducible, beta |
C00004565
|
| 2729 | GCLC, GCL, GCS, GLCL, GLCLC | glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) |
C00004565
|
| 9687 | GREB1 | growth regulation by estrogen in breast cancer 1 |
C00004565
|
| 2938 | GSTA1, GST2, GSTA1-1, GTH1 | glutathione S-transferase alpha 1 (EC:2.5.1.18) |
C00004565
|
| 2950 | GSTP1, DFN7, FAEES3, GST3, GSTP, PI | glutathione S-transferase pi 1 (EC:2.5.1.18) |
C00004565
|
| 3014 | H2AFX, H2A.X, H2A/X, H2AX | H2A histone family, member X |
C00004565
|
| 3043 | HBB, CD113t-C, beta-globin | hemoglobin, beta |
C00004565
|
| 3082 | HGF, DFNB39, F-TCF, HGFB, HPTA, SF | hepatocyte growth factor (hepapoietin A; scatter factor) |
C00004565
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00004565
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00004565
|
| 3565 | IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 | interleukin 4 |
C00004565
|
| 3567 | IL5, EDF, IL-5, TRF | interleukin 5 (colony-stimulating factor, eosinophil) |
C00004565
|
| 3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00004565
|
| 3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00004565
|
| 4297 | KMT2A, ALL-1, CXXC7, HRX, HTRX1, MLL, MLL/GAS7, MLL1A, TET1-MLL, TRX1, WDSTS | lysine (K)-specific methyltransferase 2A (EC:2.1.1.43) |
C00004565
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00004565
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00004565
|
| 4233 | MET, AUTS9, HGFR, RCCP2, c-Met | met proto-oncogene (EC:2.7.10.1) |
C00004565
|
| 110357 |
C00004565
|
||
| 4502 | MT2A, MT2 | metallothionein 2A |
C00004565
|
| 4586 | MUC5AC, MUC5, TBM, leB | mucin 5AC, oligomeric mucus/gel-forming |
C00004565
|
| 8202 | NCOA3, ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP | nuclear receptor coactivator 3 (EC:2.3.1.48) |
C00004565
|
| 4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00004565
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00004565
|
| 4843 | NOS2, HEP-NOS, INOS, NOS, NOS2A | nitric oxide synthase 2, inducible (EC:1.14.13.39) |
C00004565
|
| 8856 | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR | nuclear receptor subfamily 1, group I, member 2 |
C00004565
|
| 9970 | NR1I3, CAR, CAR1, MB67 | nuclear receptor subfamily 1, group I, member 3 |
C00004565
|
| 5241 | PGR, NR3C3, PR | progesterone receptor |
C00004565
|
| 10891 | PPARGC1A, LEM6, PGC-1(alpha), PGC-1v, PGC1, PGC1A, PPARGC1 | peroxisome proliferator-activated receptor gamma, coactivator 1 alpha |
C00004565
|
| 8000 | PSCA, PRO232 | prostate stem cell antigen |
C00004565
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00004565
|
| 6119 | RPA3, REPA3 | replication protein A3, 14kDa |
C00004565
|
| 2810 | SFN, YWHAS | stratifin |
C00004565
|
| 6513 | SLC2A1, DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED | solute carrier family 2 (facilitated glucose transporter), member 1 |
C00004565
|
| 6773 | STAT2, ISGF-3, P113, STAT113 | signal transducer and activator of transcription 2, 113kDa |
C00004565
|
| 7019 | TFAM, MTTF1, MTTFA, TCF6, TCF6L1, TCF6L2, TCF6L3 | transcription factor A, mitochondrial |
C00004565
|
| 7031 | TFF1, BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2 | trefoil factor 1 |
C00004565
|
| 7039 | TGFA, TFGA | transforming growth factor, alpha |
C00004565
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00004565
|
| 7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00004565
|
| 9540 | TP53I3, PIG3 | tumor protein p53 inducible protein 3 |
C00004565
|
| 8626 | TP63, AIS, B(p51A), B(p51B), EEC3, KET, LMS, NBP, OFC8, RHS, SHFM4, TP53CP, TP53L, TP73L, p40, p51, p53CP, p63, p73H, p73L | tumor protein p63 |
C00004565
|
| 7161 | TP73, P73 | tumor protein p73 |
C00004565
|
| 7352 | UCP3, SLC25A9 | uncoupling protein 3 (mitochondrial, proton carrier) |
C00004565
|
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) |
C00004565
|
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) |
C00004565
|
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) |
C00004565
|
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) |
C00004565
|
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) |
C00004565
|
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) |
C00004565
|
| 7402 | UTRN, DMDL, DRP, DRP1 | utrophin |
C00004565
|
| 8839 | WISP2, CCN5, CT58, CTGF-L | WNT1 inducible signaling pathway protein 2 |
C00004565
|
| 8654 | PDE5A, CGB-PDE, CN5A, PDE5 | phosphodiesterase 5A, cGMP-specific (EC:3.1.4.35) |
C00006735
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (69)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| %606641 | Body mass index; bmi |
P37231
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #608013 | Gaucher disease, perinatal lethal |
P04062
|
| #230800 | Gaucher disease, type i |
P04062
|
| #230900 | Gaucher disease, type ii |
P04062
|
| #231000 | Gaucher disease, type iii |
P04062
|
| #231005 | Gaucher disease, type iiic |
P04062
|
| #609446 | Generalized epilepsy and paroxysmal dyskinesia; gepd |
Q12791
|
| #137750 | Glaucoma 1, open angle, a; glc1a |
Q16678
|
| #231300 | Glaucoma 3, primary congenital, a; glc3a |
Q16678
|
| #137760 | Glaucoma, primary open angle; poag |
Q16678
|
| #137800 | Glioma susceptibility 1; glm1 |
P37231
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #601626 | Leukemia, acute myeloid; aml |
P36888
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04637 |
| #300635 | Lymphoproliferative syndrome, x-linked, 2; xlp2 |
P98170
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #601665 | Obesity |
P37231
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #168600 | Parkinson disease, late-onset; pd |
P04062
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #604229 | Peters anomaly |
Q16678
|
| #172700 | Pick disease of brain |
P10636
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| %612223 | Stature quantitative trait locus 11; stqtl11 |
Q00534
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #278300 | Xanthinuria, type i |
P47989
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (87)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04637 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04637 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P04637 (related) |
| H00030 | Cervical cancer |
P00533
(related)
|
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) |
| H00066 | Lewy body dementia (LBD) |
P04062
(related)
|
| H00126 | Gaucher disease |
P04062
(related)
|
| H00426 | Defects in the degradation of ganglioside |
P04062
(related)
|
| H00810 | Progressive myoclonic epilepsy (PME) |
P04062
(related)
|
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P35354 (related) |
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P27487 (marker) P37231 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
P14679 (marker) |
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
P35354 (related) |
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00003 | Acute myeloid leukemia (AML) |
P36888
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00192 | Xanthinuria |
P47989
(related)
|
| H00107 | Other well-defined immunodeficiency syndromes |
P98170
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H01258 | Generalized epilepsy and paroxysmal dyskinesia (GEPD) |
Q12791
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00612 | Primary open angle glaucoma |
Q16678
(related)
|
| H01075 | Peters anomaly |
Q16678
(related)
|
| H01159 | Anterior segment dysgenesis (ASD) |
Q16678
(related)
|
| H01203 | Primary congenital glaucoma (PCG) |
Q16678
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00480 | Non-syndromic X-linked mental retardation |
Q99714
(related)
|
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
Diseases related to CTD interactions
8 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D050197 | Atherosclerosis |
C00004565
|
| D001943 | Breast Neoplasms |
C00004565
|
| D009202 | Cardiomyopathies |
C00004565
|
| D002318 | Cardiovascular Diseases |
C00004565
|
| D006943 | Hyperglycemia |
C00004565
|
| D007938 | Leukemia |
C00004565
|
| D010024 | Osteoporosis |
C00004565
|
| D011297 | Prenatal Exposure Delayed Effects |
C00004565
|