Species

KNApSAcK Entry

Organism name Bursaria spinosa
Genus Bursaria
Family Pittosporaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Bursaria spinosa
Linked NCBI taxonomy ID 105281
Linked level species

Family

Family in NCBI taxonomy Pittosporaceae
ID 23121

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00007805 External link 512 Glucosinalbate
/ 4-Hydroxybenzyl glucosinolate
No. 158 No. 77
C00002472 External link 512 Esculin
CHEMBL359043
CHEMBL482581
CHEMBL1434042
CHEMBL1515174
CHEMBL1536019
CHEMBL1619714
CHEMBL1624854
D004929
22 / 18 / 24 0 / 1 No. 491 No. 25

Human Protein / Gene in interactions

22 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002472 1 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00002472 0 / 3
P04062 Glucosylceramidase Enzyme C00002472 6 / 4
P10253 Lysosomal alpha-glucosidase Hydrolase C00002472 1 / 1
P29466 Caspase-1 C14 C00002472 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002472 0 / 1
O15296 Arachidonate 15-lipoxygenase B Enzyme C00002472 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002472 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00002472 0 / 0
O75496 Geminin Unclassified protein C00002472 0 / 0
P42226 Signal transducer and activator of transcription 6 Unclassified protein C00002472 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00002472 0 / 0
P06280 Alpha-galactosidase A Enzyme C00002472 1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002472 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00002472 3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002472 2 / 2
P55210 Caspase-7 C14 C00002472 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002472 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002472 0 / 1
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002472 0 / 0
O00255 Menin Unclassified protein C00002472 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00002472 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#301500 Fabry disease P06280
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#232300 Glycogen storage disease ii P10253
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#168600 Parkinson disease, late-onset; pd P04062

KEGG DISEASE (24)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00125 Fabry disease P06280 (related)
H00036 Osteosarcoma P08684 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H01205 Coumarin resistance P11712 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D013272 Stomach Diseases C00002472