| Organism name | Angelica komarovii |
|---|---|
| Genus | Angelica |
| Family | Apiaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Angelica |
|---|---|
| Linked NCBI taxonomy ID | 40948 |
| Linked level | genus |
| Family in NCBI taxonomy | Apiaceae |
|---|---|
| ID | 4037 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00002477
|
Imperatorin
|
CHEMBL453805
|
C031534
|
18 / 7 / 6 | 1 / 1 | No. 606 | No. 25 |
|
|
C00030987
|
Phellopterin
|
CHEMBL452751
|
C104601
|
7 / 18 / 10 | No. 606 | No. 25 |
|
|
|
C00034737
|
Umbelliprenin
|
CHEMBL156127
|
8 / 3 / 3 | No. 2038 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00002477 C00030987 | 1 / 1 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00002477 C00034737 | 0 / 0 |
| P56817 | Beta-secretase 1 | A1A | C00002477 C00030987 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00002477 C00034737 | 0 / 0 |
| P51452 | Dual specificity protein phosphatase 3 | Ser_Thr_Tyr | C00002477 | 0 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00030987 | 1 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00002477 | 2 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002477 | 0 / 0 |
| P17405 | Sphingomyelin phosphodiesterase | Enzyme | C00034737 | 2 / 2 |
| P39748 | Flap endonuclease 1 | Enzyme | C00034737 | 0 / 0 |
| P11413 | Glucose-6-phosphate 1-dehydrogenase | Enzyme | C00030987 | 1 / 2 |
| O75496 | Geminin | Unclassified protein | C00034737 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00002477 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00030987 | 7 / 3 |
| P34969 | 5-hydroxytryptamine receptor 7 | Serotonin receptor | C00002477 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00002477 | 0 / 0 |
| P35236 | Tyrosine-protein phosphatase non-receptor type 7 | Tyr | C00002477 | 0 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00030987 | 4 / 2 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00034737 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002477 | 0 / 1 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00034737 | 0 / 0 |
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00002477 | 1 / 1 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00002477 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00030987 | 4 / 3 |
| O00167 | Eyes absent homolog 2 | Enzyme | C00002477 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00002477 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00034737 | 1 / 1 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00002477 | 1 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00002477 | 2 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00002477
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #300908 | Anemia, nonspherocytic hemolytic, due to g6pd deficiency |
P11413
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #232300 | Glycogen storage disease ii |
P10253
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #257200 | Niemann-pick disease, type a |
P17405
|
| #607616 | Niemann-pick disease, type b |
P17405
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00069 | Glycogen storage diseases (GSD) |
P10253
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00101 | Other phagocyte defects |
P11413
(related)
|
| H00668 | Anemia due to disorders of glutathione metabolism |
P11413
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00137 | Niemann-Pick disease (NPD) typeA and B |
P17405
(related)
|
| H00424 | Defects in the degradation of sphingomyelin |
P17405
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|