Rauvolfia vomitoria
Species
KNApSAcK Entry
| Organism name | Rauvolfia vomitoria |
|---|---|
| Genus | Rauvolfia |
| Family | Apocynaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Rauvolfia vomitoria |
|---|---|
| Linked NCBI taxonomy ID | 403115 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Apocynaceae |
|---|---|
| ID | 4056 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (28)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00024280
|
Purpeline
/ (+)-Purpeline |
No. 279 |
|
|||||
|
C00024293
|
Nortetraphyllicine
|
No. 279 |
|
|||||
|
C00024286
|
Vincamajoreine
/ Deacetylmajoridine / 10-Methoxytetraphyllicine |
No. 279 |
|
|||||
|
C00024285
|
Norpurpeline
/ (+/-)-Norpurpeline / N-Demethylpurpeline |
No. 279 |
|
|||||
|
C00024276
|
(+)-Mitoridine
|
No. 279 |
|
|||||
|
C00024292
|
Endolobine
|
No. 279 |
|
|||||
|
C00024278
|
(+)-Norseredamine
|
No. 279 |
|
|||||
|
C00024319
|
Seredamine
/ (+)-Seredamine |
No. 279 |
|
|||||
|
C00024306
|
10-Hydroxynortetraphyllicine
|
No. 279 |
|
|||||
|
C00024345
|
(+)-Isosandwicine
|
CHEMBL1434779
CHEMBL1452040 CHEMBL1460192 CHEMBL1515845 CHEMBL1525248 CHEMBL2105617 CHEMBL2356868 CHEMBL2357792 |
96 / 49 / 43 | No. 407 | No. 4 |
|
||
|
C00024294
|
Ritmos
/ Ignazin / Takycor / Ajmalin / Siddiqui / Rytmalin / Merabitol / Rhytmaton / Tachmalin / Rauwolfin / Rauwolfine / Raugalline / Gilurytmal / (+)-Ajmaline / Cardiorythmine |
CHEMBL1434779
CHEMBL1452040 CHEMBL1460192 CHEMBL1515845 CHEMBL1525248 CHEMBL2105617 CHEMBL2356868 CHEMBL2357792 |
D000404
|
96 / 49 / 43 | 2 / 32 | No. 407 | No. 4 |
|
|
C00024277
|
(+)-Norajmaline
|
No. 407 | No. 4 |
|
||||
|
C00024330
|
(+)-Vomalidine
|
No. 407 | No. 4 |
|
||||
|
C00024342
|
(+)-Ajmalinol
|
No. 407 | No. 4 |
|
||||
|
C00024344
|
(+)-Isoajmaline
|
CHEMBL1434779
CHEMBL1452040 CHEMBL1460192 CHEMBL1515845 CHEMBL1525248 CHEMBL2105617 CHEMBL2356868 CHEMBL2357792 |
96 / 49 / 43 | No. 407 | No. 4 |
|
||
|
C00024289
|
17-O-Acetylajmaline
|
No. 407 | No. 4 |
|
||||
|
C00024283
|
Sandwicin
/ 7-Epiajmaline / (+)-Sandwicine |
CHEMBL1434779
CHEMBL1452040 CHEMBL1460192 CHEMBL1515845 CHEMBL1525248 CHEMBL2105617 CHEMBL2356868 CHEMBL2357792 |
96 / 49 / 43 | No. 407 | No. 4 |
|
||
|
C00024281
|
Quebrachidine
/ (+)-Quebrachidine |
C010318
|
No. 507 |
|
||||
|
C00024338
|
(-)-Vomilenine
|
No. 523 | No. 4 |
|
||||
|
C00024282
|
(+)-Raucaffrinoline
|
No. 523 | No. 4 |
|
||||
|
C00024279
|
Raucaffrine
/ (+)-Perakine |
CHEMBL521036
|
No. 523 | No. 4 |
|
|||
|
C00024317
|
Norrauvomitine
|
No. 1568 |
|
|||||
|
C00024334
|
(-)-Rauvomitine
|
No. 1568 |
|
|||||
|
C00024288
|
Ajmalimine
/ 17-O-(3',4'5'-Trimethoxybenzoyl)ajmaline / Ajmaline 17-O-(3',4',5'-trimethoxybenzoate) |
No. 1568 |
|
|||||
|
C00001763
|
Reserpine
|
CHEMBL772
CHEMBL357497 CHEMBL388848 CHEMBL1315313 CHEMBL1396912 CHEMBL1433658 CHEMBL1452716 |
D012110
|
156 / 107 / 86 | 18 / 67 | No. 2040 | No. 4 |
|
|
C00001762
|
Rescinnamine
|
CHEMBL1668
CHEMBL1612623 |
28 / 26 / 30 | No. 2040 | No. 4 |
|
||
|
C00000258
|
2,6-Dimethoxy-p-benzoquinone
|
CHEMBL448515
|
C030511
|
22 / 32 / 55 | No. 2517 |
|
||
|
C00001683
|
Alstonine
|
CHEMBL14755
CHEMBL1187439 CHEMBL1994588 |
1 / 1 / 0 | No. 4006 | No. 4 |
|
Human Protein / Gene in interactions
164 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001683 C00001762 C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 0 |
| O00255 | Menin | Unclassified protein | C00000258 C00001762 C00001763 C00024283 C00024294 C00024344 C00024345 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00000258 C00001762 C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 2 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00000258 C00001762 C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001762 C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00001762 C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001762 C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001762 C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 1 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00000258 C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00000258 C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 0 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00001763 C00024283 C00024294 C00024344 C00024345 | 2 / 2 |
| P08246 | Neutrophil elastase | S1A | C00001763 C00024283 C00024294 C00024344 C00024345 | 2 / 1 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P29466 | Caspase-1 | C14 | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00001763 C00024283 C00024294 C00024344 C00024345 | 2 / 2 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 3 / 2 |
| P25105 | Platelet-activating factor receptor | PAF receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P00918 | Carbonic anhydrase 2 | Lyase | C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 2 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 1 |
| P25021 | Histamine H2 receptor | Histamine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 8 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 0 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 1 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 0 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 1 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00001763 C00024283 C00024294 C00024344 C00024345 | 2 / 1 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 1 |
| P06239 | Tyrosine-protein kinase Lck | Src | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 1 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 3 |
| P41143 | Delta-type opioid receptor | Opioid receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P08311 | Cathepsin G | S1A | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 3 / 0 |
| P03956 | Interstitial collagenase | M10A | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00000258 C00024283 C00024294 C00024344 C00024345 | 7 / 3 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 1 / 0 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00001763 C00024283 C00024294 C00024344 C00024345 | 5 / 9 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | C00001763 C00024283 C00024294 C00024344 C00024345 | 2 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 2 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00001763 C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00024283 C00024294 C00024344 C00024345 | 0 / 0 |
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00000258 C00001762 C00001763 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00000258 C00001762 C00001763 | 2 / 3 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00000258 C00001762 C00001763 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00000258 C00001762 C00001763 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00000258 C00001762 C00001763 | 1 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000258 C00001763 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00000258 C00001763 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00001762 C00001763 | 1 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001762 C00001763 | 0 / 0 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00001762 C00001763 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00000258 C00001762 | 2 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00000258 C00001763 | 0 / 0 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00001762 C00001763 | 0 / 0 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00000258 C00001763 | 4 / 1 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00001762 C00001763 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00000258 C00001763 | 4 / 3 |
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00001762 C00001763 | 2 / 2 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00001762 C00001763 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00000258 C00001763 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00001762 C00001763 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00001762 C00001763 | 0 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00001762 C00001763 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00001762 C00001763 | 11 / 10 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00001762 C00001763 | 1 / 4 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00001762 C00001763 | 0 / 0 |
| Q9Y6L6 | Solute carrier organic anion transporter family member 1B1 | Electrochemical transporter | C00001763 | 1 / 0 |
| P54132 | Bloom syndrome protein | Enzyme | C00001763 | 1 / 2 |
| P08183 | Multidrug resistance protein 1 | drug | C00001763 | 1 / 0 |
| P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00001763 | 0 / 0 |
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00001763 | 3 / 1 |
| O15296 | Arachidonate 15-lipoxygenase B | Enzyme | C00001763 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00001763 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001763 | 0 / 0 |
| P55210 | Caspase-7 | C14 | C00001763 | 0 / 0 |
| P68871 | Hemoglobin subunit beta | Secreted protein | C00001763 | 4 / 4 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00001763 | 0 / 0 |
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00001763 | 0 / 0 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00001763 | 0 / 0 |
| Q6W5P4 | Neuropeptide S receptor | Neuropeptide receptor | C00001763 | 1 / 0 |
| Q01453 | Peripheral myelin protein 22 | Unclassified protein | C00001763 | 5 / 2 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001763 | 0 / 0 |
| Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00001763 | 1 / 1 |
| Q99549 | M-phase phosphoprotein 8 | Unclassified protein | C00001763 | 0 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00001763 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00001763 | 3 / 4 |
| O95342 | Bile salt export pump | drug | C00001763 | 2 / 1 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00001763 | 2 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00000258 | 1 / 1 |
| O94956 | Solute carrier organic anion transporter family member 2B1 | Unclassified protein | C00001763 | 0 / 0 |
| Q9UNQ0 | ATP-binding cassette sub-family G member 2 | ATP binding cassette | C00001763 | 2 / 0 |
| Q9NR56 | Muscleblind-like protein 1 | Unclassified protein | C00001763 | 1 / 0 |
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00001763 | 3 / 3 |
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00001763 | 0 / 0 |
| P40225 | Thrombopoietin | Unclassified protein | C00001763 | 1 / 1 |
| Q2TB90 | Putative hexokinase HKDC1 | Enzyme | C00000258 | 0 / 0 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00001763 | 0 / 0 |
| P10145 | Interleukin-8 | Secreted protein | C00001763 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00001763 | 1 / 1 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00001763 | 0 / 0 |
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00000258 | 7 / 37 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00001763 | 0 / 0 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00001763 | 5 / 3 |
| Q9NY46 | Sodium channel protein type 3 subunit alpha | SCN alpha, NaV1.x | C00001763 | 0 / 0 |
| Q99250 | Sodium channel protein type 2 subunit alpha | SCN alpha, NaV1.x | C00001763 | 2 / 2 |
| P35498 | Sodium channel protein type 1 subunit alpha | SCN alpha, NaV1.x | C00001763 | 3 / 2 |
| Q9NPD5 | Solute carrier organic anion transporter family member 1B3 | Electrochemical transporter | C00001763 | 1 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00000258 | 2 / 1 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00001762 | 1 / 1 |
19 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 3757 | KCNH2, ERG1, HERG, HERG1, Kv11.1, LQT2, SQT1 | potassium voltage-gated channel, subfamily H (eag-related), member 2 |
C00001763
C00024294
|
| 1576 | CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 | cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) |
C00001763
|
| 5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00001763
|
| 8647 | ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP | ATP-binding cassette, sub-family B (MDR/TAP), member 11 |
C00001763
|
| 9429 | ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1 | ATP-binding cassette, sub-family G (WHITE), member 2 |
C00001763
|
| 332 | BIRC5, API4, EPR-1 | baculoviral IAP repeat containing 5 |
C00001763
|
| 595 | CCND1, BCL1, D11S287E, PRAD1, U21B31 | cyclin D1 |
C00001763
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001763
|
| 1555 | CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450 | cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1) |
C00001763
|
| 6331 | SCN5A, CDCD2, CMD1E, CMPD2, HB1, HB2, HBBD, HH1, ICCD, IVF, LQT3, Nav1.5, PFHB1, SSS1, VF1 | sodium channel, voltage-gated, type V, alpha subunit |
C00024294
|
| 1577 | CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 | cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1) |
C00001763
|
| 3586 | IL10, CSIF, GVHDS, IL-10, IL10A, TGIF | interleukin 10 |
C00001763
|
| 3738 | KCNA3, HGK5, HLK3, HPCN3, HUKIII, KV1.3, MK3, PCN3 | potassium voltage-gated channel, shaker-related subfamily, member 3 |
C00001763
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00001763
|
| 8856 | NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR | nuclear receptor subfamily 1, group I, member 2 |
C00001763
|
| 9970 | NR1I3, CAR, CAR1, MB67 | nuclear receptor subfamily 1, group I, member 3 |
C00001763
|
| 6477 | SIAH1, SIAH1A | siah E3 ubiquitin protein ligase 1 (EC:6.3.2.-) |
C00001763
|
| 6570 | SLC18A1, CGAT, VAT1, VMAT1 | solute carrier family 18 (vesicular monoamine transporter), member 1 |
C00001763
|
| 6571 | SLC18A2, SVAT, SVMT, VAT2, VMAT2 | solute carrier family 18 (vesicular monoamine transporter), member 2 |
C00001763
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (125)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency |
Q99714
|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #608584 | Asthma-related traits, susceptibility to, 2 |
Q6W5P4
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #613985 | Beta-thalassemia |
P68871
|
| #603902 | Beta-thalassemia, dominant inclusion body type |
P68871
|
| #614490 | Blood group, junior system; jr |
Q9UNQ0
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| %606641 | Body mass index; bmi |
P37231
|
| #300615 | Brunner syndrome |
P21397
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #118300 | Charcot-marie-tooth disease and deafness |
Q01453
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #118220 | Charcot-marie-tooth disease, demyelinating, type 1a; cmt1a |
Q01453
|
| #605479 | Cholestasis, benign recurrent intrahepatic, 2; bric2 |
O95342
|
| #601847 | Cholestasis, progressive familial intrahepatic, 2; pfic2 |
O95342
|
| #114500 | Colorectal cancer; crc |
P84022
Q14191 |
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #119900 | Digital clubbing, isolated congenital |
P15428
|
| #607208 | Dravet syndrome |
P35498
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #237500 | Dubin-johnson syndrome; djs |
Q92887
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #613721 | Epileptic encephalopathy, early infantile, 11; eiee11 |
Q99250
|
| #133239 | Esophageal cancer |
P04637
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #604403 | Generalized epilepsy with febrile seizures plus, type 2; gefsp2 |
P35498
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P04626 P37231 |
| #139393 | Guillain-barre syndrome, familial; gbs |
Q01453
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #140700 | Heinz body anemias |
P68871
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #237450 | Hyperbilirubinemia, rotor type; hblrr |
Q9NPD5
Q9Y6L6 |
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #145900 | Hypertrophic neuropathy of dejerine-sottas |
Q01453
|
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 P04637 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #300705 | Mental retardation, x-linked 17; mrx17 |
Q99714
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 |
Q99714
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #609634 | Migraine, familial hemiplegic, 3; fhm3 |
P35498
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #159900 | Myoclonic dystonia |
P14416
|
| #160900 | Myotonic dystrophy 1; dm1 |
Q9NR56
|
| #162500 | Neuropathy, hereditary, with liability to pressure palsies; hnpp |
Q01453
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #601665 | Obesity |
P32245
P37231 |
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #607745 | Seizures, benign familial infantile, 3; bfis3 |
Q99250
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #603903 | Sickle cell anemia |
P68871
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #187950 | Thrombocythemia 1; thcyt1 |
P40225
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #138900 | Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 |
Q9UNQ0
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (108)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
P04637 (related) |
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00624 | Familial cholestasis |
O95342
(related)
|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P04637 (related) P04637 (marker) P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) P04637 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) P04637 (related) P68871 (marker) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) P04637 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) P04637 (related) P04637 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
Q01453 (related) |
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
P37231 (related) |
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) P04637 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
P04637 (related) P04637 (marker) |
| H00027 | Ovarian cancer |
P04626
(related)
P04637 (related) |
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) P04637 (related) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P04637 (related) P35354 (related) |
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
Q01196 (related) |
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) P68871 (marker) |
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) P14780 (related) P35354 (related) |
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
| H00036 | Osteosarcoma |
P04637
(related)
P08684 (marker) |
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
Q13148 (related) |
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
| H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00775 | Familial or sporadic hemiplegic migraine |
P35498
(related)
|
| H00783 | Febrile seizures |
P35498
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00227 | Congenital amegakaryocytic thrombocytopenia (CAMT) |
P40225
(marker)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
Q99714 (related) |
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00228 | Thalassemia |
P68871
(related)
|
| H00229 | Sickle cell anemia (SCA) |
P68871
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) Q03164 (related) Q03164 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H01296 | Hereditary neuropathy with liability to pressure palsies (HNPP) |
Q01453
(related)
|
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00208 | Hyperbilirubinemia |
Q92887
(related)
|
| H00606 | Early infantile epileptic encephalopathy |
Q99250
(related)
|
| H00806 | Benign familial neonatal and infantile epilepsies |
Q99250
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
Q9NUW8 (related) |
| H00658 | Syndromic X-linked mental retardation |
Q99714
(related)
|
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency |
Q99714
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|
Diseases related to CTD interactions
95 disease in interactions with metabolites
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D001145 | Arrhythmias, Cardiac |
C00024294
C00001763 |
| D005334 | Fever |
C00024294
C00001763 |
| D064420 | Drug-Related Side Effects and Adverse Reactions |
C00024294
C00001763 |
| D056486 | Drug-Induced Liver Injury |
C00024294
C00001763 |
| D008569 | Memory Disorders |
C00001763
|
| D001281 | Atrial Fibrillation |
C00024294
|
| D054537 | Atrioventricular Block |
C00024294
|
| C535438 | Bidirectional tachycardia |
C00024294
|
| D053840 | Brugada Syndrome |
C00024294
|
| D002037 | Bundle-Branch Block |
C00024294
|
| D023341 | Chills |
C00024294
|
| D002779 | Cholestasis |
C00024294
|
| D002780 | Cholestasis, Intrahepatic |
C00024294
|
| D004342 | Drug Hypersensitivity |
C00024294
|
| D001002 | Anuria |
C00024294
|
| D056487 | Drug-Induced Liver Injury, Chronic |
C00024294
|
| D000743 | Anemia, Hemolytic |
C00024294
|
| D004802 | Eosinophilia |
C00024294
|
| D058186 | Acute Kidney Injury |
C00024294
|
| D006461 | Hemolysis |
C00024294
|
| D006505 | Hepatitis |
C00024294
|
| D007565 | Jaundice |
C00024294
|
| D009461 | Neurologic Manifestations |
C00024294
|
| D011537 | Pruritus |
C00024294
|
| D013611 | Tachycardia, Atrioventricular Nodal Reentry |
C00024294
|
| D013617 | Tachycardia, Supraventricular |
C00024294
|
| D017180 | Tachycardia, Ventricular |
C00024294
|
| D013921 | Thrombocytopenia |
C00024294
|
| D016171 | Torsades de Pointes |
C00024294
|
| D014693 | Ventricular Fibrillation |
C00024294
|
| D018879 | Ventricular Premature Complexes |
C00024294
|
| D014973 | Xanthomatosis |
C00024294
|
| D000544 | Alzheimer Disease |
C00001763
|
| D000855 | Anorexia |
C00001763
|
| D001161 | Arteriosclerosis |
C00001763
|
| D001714 | Bipolar Disorder |
C00001763
|
| D001763 | Blepharoptosis |
C00001763
|
| D001919 | Bradycardia |
C00001763
|
| D001943 | Breast Neoplasms |
C00001763
|
| D009202 | Cardiomyopathies |
C00001763
|
| D002375 | Catalepsy |
C00001763
|
| D002389 | Catatonia |
C00001763
|
| D002493 | Central Nervous System Diseases |
C00001763
|
| D002819 | Chorea |
C00001763
|
| D019970 | Cocaine-Related Disorders |
C00001763
|
| D003866 | Depressive Disorder |
C00001763
|
| D004195 | Disease Models, Animal |
C00001763
|
| D004409 | Dyskinesia, Drug-Induced |
C00001763
|
| D020820 | Dyskinesias |
C00001763
|
| D005183 | Failure to Thrive |
C00001763
|
| D005221 | Fatigue |
C00001763
|
| D005313 | Fetal Death |
C00001763
|
| D005767 | Gastrointestinal Diseases |
C00001763
|
| D005921 | Glomerulonephritis |
C00001763
|
| D005923 | Glomerulosclerosis, Focal Segmental |
C00001763
|
| D006323 | Heart Arrest |
C00001763
|
| D006327 | Heart Block |
C00001763
|
| D006396 | Hematemesis |
C00001763
|
| D006930 | Hyperalgesia |
C00001763
|
| D006948 | Hyperkinesis |
C00001763
|
| D006965 | Hyperplasia |
C00001763
|
| D006966 | Hyperprolactinemia |
C00001763
|
| D006973 | Hypertension |
C00001763
|
| D006980 | Hyperthyroidism |
C00001763
|
| D018476 | Hypokinesia |
C00001763
|
| D007022 | Hypotension |
C00001763
|
| D007035 | Hypothermia |
C00001763
|
| D007154 | Immune System Diseases |
C00001763
|
| D007674 | Kidney Diseases |
C00001763
|
| D008325 | Mammary Neoplasms, Experimental |
C00001763
|
| D015746 | Abdominal Pain |
C00024294
|
| D001523 | Mental Disorders |
C00001763
|
| D017240 | Mitochondrial Myopathies |
C00001763
|
| D009069 | Movement Disorders |
C00001763
|
| D009127 | Muscle Rigidity |
C00001763
|
| D009203 | Myocardial Infarction |
C00001763
|
| D009207 | Myoclonus |
C00001763
|
| D009325 | Nausea |
C00001763
|
| D009374 | Neoplasms, Experimental |
C00001763
|
| D016584 | Panic Disorder |
C00001763
|
| D010243 | Paralysis |
C00001763
|
| D010302 | Parkinson Disease, Secondary |
C00001763
|
| D020734 | Parkinsonian Disorders |
C00001763
|
| D010468 | Perceptual Disorders |
C00001763
|
| D010673 | Pheochromocytoma |
C00001763
|
| D010488 | Polyarteritis Nodosa |
C00001763
|
| D011297 | Prenatal Exposure Delayed Effects |
C00001763
|
| D012021 | Reflex, Abnormal |
C00001763
|
| D012559 | Schizophrenia |
C00001763
|
| D012640 | Seizures |
C00001763
|
| D012893 | Sleep Disorders |
C00001763
|
| D013276 | Stomach Ulcer |
C00001763
|
| D013610 | Tachycardia |
C00001763
|
| D014202 | Tremor |
C00001763
|
| D014456 | Ulcer |
C00001763
|