| Organism name | Schleichera oleosa | 
|---|---|
| Genus | Schleichera | 
| Family | Sapindaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Schleichera oleosa | 
|---|---|
| Linked NCBI taxonomy ID | 290996 | 
| Linked level | species | 
| Family in NCBI taxonomy | Sapindaceae | 
|---|---|
| ID | 23672 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | rosids | 
|---|---|
| ID | 71275 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00003740   | Betulin | CHEMBL23236 CHEMBL140040 CHEMBL1610940 CHEMBL2000891 CHEMBL2069124 | C002503 | 18 / 16 / 17 | 0 / 2 | No. 23 | No. 51 |   | 
| C00003750   | Lupeol acetate | CHEMBL453802 CHEMBL1097034 | C055329 | 1 / 0 / 0 | No. 23 | No. 51 |   | |
| C00003749   | Lupeol / Lupenol / (+)-Lupenol | CHEMBL289191 CHEMBL459702 | C010480 | 3 / 0 / 0 | 2 / 6 | No. 23 | No. 51 |   | 
| C00003741   | Betulinic acid | CHEMBL269277 CHEMBL71690 CHEMBL519059 CHEMBL1318530 CHEMBL2005635 | C002070 | 34 / 17 / 14 | 10 / 2 | No. 23 | No. 51 |   | 
| C00046908   | Schleicheol 1 / (+)-Schleicheol 1 | CHEMBL481459 CHEMBL479305 | No. 53 | No. 11 |   | |||
| C00003672   | Sitosterol / beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol | CHEMBL221542 CHEMBL1398443 CHEMBL1875388 | 17 / 19 / 12 | No. 53 | No. 11 |   | ||
| C00046916   | Schleicherastatin 7 / (-)-Schleicherastatin 7 | CHEMBL480674 CHEMBL482250 | No. 53 | No. 11 |   | |||
| C00046915   | Schleicherastatin 6 / (-)-Schleicherastatin 6 | CHEMBL480674 CHEMBL482250 | No. 53 | No. 11 |   | |||
| C00046910   | Schleicherastatin 1 / (+)-Schleicherastatin 1 | CHEMBL481652 CHEMBL481653 | No. 53 | No. 11 |   | |||
| C00046911   | Schleicherastatin 2 / (-)-Schleicherastatin 2 | CHEMBL481652 CHEMBL481653 | No. 53 | No. 11 |   | |||
| C00046912   | Schleicherastatin 3 / (+)-Schleicherastatin 3 | CHEMBL481654 CHEMBL480672 | No. 53 | No. 11 |   | |||
| C00046913   | Schleicherastatin 4 / (-)-Schleicherastatin 4 | CHEMBL481654 CHEMBL480672 | No. 53 | No. 11 |   | |||
| C00046914   | Schleicherastatin 5 / (-)-Schleicherastatin 5 | CHEMBL480673 | No. 53 | No. 11 |   | |||
| C00046909   | Schleicheol 2 / (-)-Schleicheol 2 | CHEMBL481459 CHEMBL479305 | No. 53 | No. 11 |   | |||
| C00002499   | Scopoletin | CHEMBL71851 | D012603 | 48 / 37 / 34 | 9 / 0 | No. 864 | No. 25 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00002499 C00003672 C00003740 C00003741 | 1 / 0 | 
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00002499 C00003672 C00003740 C00003741 | 0 / 1 | 
| P11388 | DNA topoisomerase 2-alpha | Isomerase | C00003740 C00003741 C00003749 C00003750 | 0 / 0 | 
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00002499 C00003672 C00003740 C00003741 | 1 / 1 | 
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00002499 C00003672 C00003740 C00003741 | 0 / 0 | 
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00002499 C00003672 C00003740 C00003741 | 0 / 1 | 
| P11387 | DNA topoisomerase 1 | Isomerase | C00003740 C00003741 C00003749 | 0 / 0 | 
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00002499 C00003672 C00003740 | 0 / 0 | 
| Q16665 | Hypoxia-inducible factor 1-alpha | Transcription Factor | C00002499 C00003740 C00003741 | 0 / 0 | 
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00003672 C00003741 | 0 / 0 | 
| P06746 | DNA polymerase beta | Enzyme | C00003672 C00003741 | 0 / 0 | 
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00002499 C00003740 | 0 / 3 | 
| P15121 | Aldose reductase | Enzyme | C00002499 C00003741 | 0 / 0 | 
| O75496 | Geminin | Unclassified protein | C00002499 C00003741 | 0 / 0 | 
| Q04206 | Transcription factor p65 | Transcription Factor | C00002499 C00003741 | 0 / 0 | 
| Q96RI1 | Bile acid receptor | NR1H4 | C00003740 C00003741 | 0 / 0 | 
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003672 C00003741 | 2 / 0 | 
| P05771 | Protein kinase C beta type | Alpha | C00003740 C00003741 | 0 / 0 | 
| Q8TDU6 | G-protein coupled bile acid receptor 1 | Steroid-like ligand receptor | C00003740 C00003741 | 0 / 0 | 
| O75604 | Ubiquitin carboxyl-terminal hydrolase 2 | Enzyme | C00003740 C00003741 | 0 / 0 | 
| P08047 | Transcription factor Sp1 | Unclassified protein | C00003672 C00003749 | 0 / 0 | 
| Q02156 | Protein kinase C epsilon type | Eta | C00003740 C00003741 | 0 / 0 | 
| P02545 | Prelamin-A/C | Unclassified protein | C00003740 C00003741 | 11 / 10 | 
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00003672 | 3 / 2 | 
| P47989 | Xanthine dehydrogenase/oxidase | Oxidoreductase | C00002499 | 1 / 1 | 
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00003740 | 3 / 1 | 
| P00918 | Carbonic anhydrase 2 | Lyase | C00002499 | 1 / 2 | 
| P55789 | FAD-linked sulfhydryl oxidase ALR | Enzyme | C00002499 | 1 / 0 | 
| P08183 | Multidrug resistance protein 1 | drug | C00003672 | 1 / 0 | 
| Q8N1Q1 | Carbonic anhydrase 13 | Lyase | C00002499 | 0 / 0 | 
| P15559 | NAD(P)H dehydrogenase [quinone] 1 | Enzyme | C00003741 | 0 / 0 | 
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00002499 | 0 / 0 | 
| P04406 | Glyceraldehyde-3-phosphate dehydrogenase | Enzyme | C00002499 | 0 / 0 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00002499 | 0 / 0 | 
| O43570 | Carbonic anhydrase 12 | Lyase | C00002499 | 1 / 2 | 
| P29466 | Caspase-1 | C14 | C00002499 | 0 / 0 | 
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00002499 | 0 / 0 | 
| P08151 | Zinc finger protein GLI1 | Unclassified protein | C00003741 | 0 / 0 | 
| P43166 | Carbonic anhydrase 7 | Lyase | C00002499 | 0 / 0 | 
| O60656 | UDP-glucuronosyltransferase 1-9 | Enzyme | C00002499 | 0 / 0 | 
| P54855 | UDP-glucuronosyltransferase 2B15 | Enzyme | C00002499 | 0 / 0 | 
| P10253 | Lysosomal alpha-glucosidase | Hydrolase | C00002499 | 1 / 1 | 
| P00915 | Carbonic anhydrase 1 | Lyase | C00002499 | 0 / 0 | 
| P04062 | Glucosylceramidase | Enzyme | C00002499 | 6 / 4 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00003741 | 0 / 0 | 
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00002499 | 7 / 3 | 
| P09917 | Arachidonate 5-lipoxygenase | Oxidoreductase | C00002499 | 0 / 0 | 
| Q9Y253 | DNA polymerase eta | Enzyme | C00003741 | 1 / 1 | 
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00003741 | 0 / 0 | 
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00003740 | 0 / 0 | 
| P00734 | Prothrombin | S1A | C00003672 | 4 / 2 | 
| P14679 | Tyrosinase | Oxidoreductase | C00003672 | 4 / 2 | 
| P06280 | Alpha-galactosidase A | Enzyme | C00002499 | 1 / 1 | 
| O60218 | Aldo-keto reductase family 1 member B10 | Enzyme | C00003741 | 0 / 0 | 
| Q13133 | Oxysterols receptor LXR-alpha | NR1H3 | C00003741 | 0 / 0 | 
| Q99700 | Ataxin-2 | Unclassified protein | C00002499 | 1 / 1 | 
| Q16790 | Carbonic anhydrase 9 | Lyase | C00002499 | 0 / 1 | 
| P55055 | Oxysterols receptor LXR-beta | NR1H3 | C00003741 | 0 / 0 | 
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00002499 | 3 / 3 | 
| P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00002499 | 2 / 2 | 
| Q9HAW9 | UDP-glucuronosyltransferase 1-8 | Enzyme | C00002499 | 0 / 0 | 
| Q9Y4X1 | UDP-glucuronosyltransferase 2A1 | Enzyme | C00002499 | 0 / 0 | 
| P03372 | Estrogen receptor | NR3A1 | C00003672 | 1 / 1 | 
| P22303 | Acetylcholinesterase | Hydrolase | C00002499 | 1 / 0 | 
| Q00796 | Sorbitol dehydrogenase | Enzyme | C00002499 | 0 / 0 | 
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00003741 | 0 / 0 | 
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00002499 | 0 / 0 | 
| P55210 | Caspase-7 | C14 | C00002499 | 0 / 0 | 
| O75795 | UDP-glucuronosyltransferase 2B17 | Enzyme | C00002499 | 1 / 0 | 
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00002499 | 3 / 0 | 
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00002499 | 5 / 1 | 
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00003672 | 1 / 1 | 
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00003741 | 0 / 0 | 
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00002499 | 0 / 0 | 
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00002499 | 0 / 0 | 
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00002499 | 0 / 0 | 
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00003672 | 1 / 1 | 
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00003741 | 1 / 0 | 
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00003741 | 0 / 0 | 
| O00255 | Menin | Unclassified protein | C00002499 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00002499 | 1 / 2 | 
| Q9UBT2 | SUMO-activating enzyme subunit 2 | Enzyme | C00003741 | 0 / 0 | 
| Q9UBE0 | SUMO-activating enzyme subunit 1 | Unclassified protein | C00003741 | 0 / 0 | 
| gene | gene name | gene description | KNApSAcK metabolite in interactions | 
|---|---|---|---|
| 207 | AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA | v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1) | C00003741 | 
| 581 | BAX, BCL2L4 | BCL2-associated X protein | C00003741 | 
| 332 | BIRC5, API4, EPR-1 | baculoviral IAP repeat containing 5 | C00003741 | 
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | C00003741 | 
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) | C00003741 | 
| 1956 | EGFR, ERBB, ERBB1, HER1, PIG61, mENA | epidermal growth factor receptor (EC:2.7.10.1) | C00003741 | 
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) | C00003741 | 
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) | C00003741 | 
| 7150 | TOP1, TOPI | topoisomerase (DNA) I (EC:5.99.1.2) | C00003741 | 
| 7153 | TOP2A, TOP2, TP2A | topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3) | C00003741 | 
| 1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa | C00003749 | 
| 5728 | PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 | phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) | C00003749 | 
| 54658 | UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A | UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) | C00002499 | 
| 54575 | UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J | UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) | C00002499 | 
| 54659 | UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C | UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) | C00002499 | 
| 54578 | UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F | UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) | C00002499 | 
| 54577 | UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G | UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) | C00002499 | 
| 54576 | UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H | UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) | C00002499 | 
| 54600 | UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I | UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) | C00002499 | 
| 7366 | UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8 | UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17) | C00002499 | 
| 7508 | XPC, RAD4, XP3, XPCC | xeroderma pigmentosum, complementation group C | C00002499 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency | Q99714 | 
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah | P63092 | 
| #103470 | Albinism, ocular, with sensorineural deafness | P14679 | 
| #203100 | Albinism, oculocutaneous, type ia; oca1a | P14679 | 
| #606952 | Albinism, oculocutaneous, type ib; oca1b | P14679 | 
| #218030 | Apparent mineralocorticoid excess; ame | P80365 | 
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 | P22309 | 
| #612560 | Bone mineral density quantitative trait locus 12; bmnd12 | O75795 | 
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a | P02545 | 
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism | P02545 | 
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 | P02545 | 
| #218800 | Crigler-najjar syndrome, type i | P22309 P22310 | 
| #606785 | Crigler-najjar syndrome, type ii | P22309 P22310 | 
| #119900 | Digital clubbing, isolated congenital | P15428 | 
| #609535 | Drug metabolism, poor, cyp2c19-related | P33261 | 
| #608902 | Drug metabolism, poor, cyp2d6-related | P10635 | 
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 | P02545 | 
| #615363 | Estrogen resistance; estrr | P03372 | 
| #301500 | Fabry disease | P06280 | 
| #608013 | Gaucher disease, perinatal lethal | P04062 | 
| #230800 | Gaucher disease, type i | P04062 | 
| #230900 | Gaucher disease, type ii | P04062 | 
| #231000 | Gaucher disease, type iii | P04062 | 
| #231005 | Gaucher disease, type iiic | P04062 | 
| #143500 | Gilbert syndrome | P22309 P22310 | 
| #137800 | Glioma susceptibility 1; glm1 | O75874 | 
| #232300 | Glycogen storage disease ii | P10253 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #610140 | Heart-hand syndrome, slovenian type | P02545 | 
| #176670 | Hutchinson-gilford progeria syndrome; hgps | P02545 | 
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn | P22309 | 
| #143860 | Hyperchlorhidrosis, isolated | O43570 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #603373 | Hyperthyroidism, familial gestational | P16473 | 
| #609152 | Hyperthyroidism, nonautoimmune | P16473 | 
| #259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 | P15428 | 
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 | P16473 | 
| #612244 | Inflammatory bowel disease 13; ibd13 | P08183 | 
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 | P02545 | 
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada | P02545 | 
| #174800 | Mccune-albright syndrome; mas | P63092 | 
| #300705 | Mental retardation, x-linked 17; mrx17 | Q99714 | 
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 | Q99714 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #613205 | Muscular dystrophy, congenital, lmna-related | P02545 | 
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b | P02545 | 
| #613076 | Myopathy, mitochondrial progressive, with congenital cataract, hearing loss, and developmental delay | P55789 | 
| #166350 | Osseous heteroplasia, progressive; poh | P63092 | 
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 | P00918 | 
| #168600 | Parkinson disease, late-onset; pd | P04062 | 
| #102200 | Pituitary adenoma, growth hormone-secreting | P63092 | 
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 | P00734 | 
| #613679 | Prothrombin deficiency, congenital | P00734 | 
| #103580 | Pseudohypoparathyroidism, type ia; php1a | P63092 | 
| #603233 | Pseudohypoparathyroidism, type ib; php1b | P63092 | 
| #612462 | Pseudohypoparathyroidism, type ic; php1c | P63092 | 
| #275210 | Restrictive dermopathy, lethal | P02545 | 
| #604906 | Schizophrenia 9; sczd9 | P49798 | 
| #181500 | Schizophrenia; sczd | P49798 | 
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 | P14679 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 | Q9NUW8 | 
| #601367 | Stroke, ischemic | P00734 | 
| #188050 | Thrombophilia due to thrombin defect; thph1 | P00734 | 
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth | P10828 | 
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth | P10828 | 
| #145650 | Thyroid hormone resistance, selective pituitary; prth | P10828 | 
| #278300 | Xanthinuria, type i | P47989 | 
| #278750 | Xeroderma pigmentosum, variant type; xpv | Q9Y253 | 
| #112100 | Yt blood group antigen | P22303 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H01302 | Hyperchlorhidrosis isolated (HCHLH) | O43570
                            (related) | 
| H00021 | Renal cell carcinoma | O43570
                            (marker) Q16790 (marker) | 
| H00223 | Inherited thrombophilia | P00734
                            (related) | 
| H01254 | Congenital prothrombin deficiency | P00734
                            (related) | 
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) | P00918
                            (related) | 
| H00436 | Osteopetrosis | P00918
                            (related) | 
| H00264 | Charcot-Marie-Tooth disease (CMT) | P02545
                            (related) | 
| H00294 | Dilated cardiomyopathy (DCM) | P02545
                            (related) | 
| H00420 | Familial partial lipodystrophy (FPL) | P02545
                            (related) | 
| H00563 | Emery-Dreifuss muscular dystrophy | P02545
                            (related) | 
| H00590 | Congenital muscular dystrophies (CMD/MDC) | P02545
                            (related) | 
| H00593 | Limb-girdle muscular dystrophy (LGMD) | P02545
                            (related) | 
| H00601 | Hutchinson-Gilford progeria syndrome | P02545
                            (related) | 
| H00663 | Restrictive dermopathy | P02545
                            (related) | 
| H00665 | Mandibuloacral dysplasia | P02545
                            (related) | 
| H01216 | Left ventricular noncompaction (LVNC) | P02545
                            (related) | 
| H00026 | Endometrial Cancer | P03372
                            (marker) | 
| H00066 | Lewy body dementia (LBD) | P04062
                            (related) | 
| H00126 | Gaucher disease | P04062
                            (related) | 
| H00426 | Defects in the degradation of ganglioside | P04062
                            (related) | 
| H00810 | Progressive myoclonic epilepsy (PME) | P04062
                            (related) | 
| H00125 | Fabry disease | P06280
                            (related) | 
| H00036 | Osteosarcoma | P08684
                            (marker) | 
| H00069 | Glycogen storage diseases (GSD) | P10253
                            (related) | 
| H00249 | Thyroid hormone resistance syndrome | P10828
                            (related) | 
| H01205 | Coumarin resistance | P11712
                            (related) | 
| H00168 | Oculocutaneous albinism (OCA) | P14679
                            (related) | 
| H00038 | Malignant melanoma | P14679
                            (marker) | 
| H00457 | Primary hypertrophic osteoarthropathy (PHO) | P15428
                            (related) | 
| H01246 | Isolated congenital nail clubbing (ICNC) | P15428
                            (related) | 
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) | P16473
                            (related) | 
| H01269 | Congenital hyperthyroidism | P16473
                            (related) | 
| H00208 | Hyperbilirubinemia | P22309
                            (related) | 
| H01171 | Poor drug metabolism (PM) | P33261
                            (related) | 
| H00017 | Esophageal cancer | P35354
                            (related) | 
| H00025 | Penile cancer | P35354
                            (related) | 
| H00046 | Cholangiocarcinoma | P35354
                            (related) | 
| H00192 | Xanthinuria | P47989
                            (related) | 
| H00244 | Pseudohypoparathyroidism | P63092
                            (related) | 
| H00441 | Progressive osseous heteroplasia (POH) | P63092
                            (related) | 
| H00501 | Fibrous dysplasia, polyostotic | P63092
                            (related) | 
| H00259 | Apparent mineralocorticoid excess syndrome | P80365
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q03164
                            (related) Q03164 (marker) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) Q9NUW8 (related) | 
| H00480 | Non-syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00658 | Syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency | Q99714
                            (related) | 
| H00403 | Disorders of nucleotide excision repair | Q9Y253
                            (related) | 
| MESH or OMIM | name | KNApSAcK metabolite | 
|---|---|---|
| D008103 | Liver Cirrhosis | C00003741 | 
| D008545 | Melanoma | C00003741 | 
| D003110 | Colonic Neoplasms | C00003740 | 
| D064420 | Drug-Related Side Effects and Adverse Reactions | C00003740 | 
| D006528 | Carcinoma, Hepatocellular | C00003749 | 
| D009202 | Cardiomyopathies | C00003749 | 
| D006937 | Hypercholesterolemia | C00003749 | 
| D009374 | Neoplasms, Experimental | C00003749 | 
| D012878 | Skin Neoplasms | C00003749 | 
| D014947 | Wounds and Injuries | C00003749 |