Centrosema haitiense

• Index
• Plant Species
• Metabolite list (3)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Centrosema haitiense
Genus	Centrosema
Family	Fabaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Centrosema
Linked NCBI taxonomy ID	167616
Linked level	genus

Family

Family in NCBI taxonomy	Fabaceae
ID	3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	rosids
ID	71275

Metabolite list (3)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00009392	Glycitein / 7,4'-Dihydroxy-6-methoxyisoflavone	CHEMBL513024	C086566	2 / 2 / 2	40 / 4	No. 3	No. 15
C00002507	Castanin / Afromosin / Afrormosin / 7-Hydroxy-6,4'-dimethoxyisoflavone	CHEMBL464404	C080240	7 / 14 / 39	1 / 0	No. 35	No. 15
C00009385	Demethyltexasin	CHEMBL239156		8 / 8 / 4		No. 71	No. 15

Human Protein / Gene in interactions

16 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00009385 C00009392	1 / 1
P38398	Breast cancer type 1 susceptibility protein	Enzyme	C00002507	4 / 2
P04637	Cellular tumor antigen p53	Transcription Factor	C00002507	7 / 37
P11388	DNA topoisomerase 2-alpha	Isomerase	C00009385	0 / 0
O15296	Arachidonate 15-lipoxygenase B	Enzyme	C00009385	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00002507	2 / 2
O75496	Geminin	Unclassified protein	C00002507	0 / 0
P51151	Ras-related protein Rab-9A	Unclassified protein	C00002507	0 / 0
Q03181	Peroxisome proliferator-activated receptor delta	NR1C2	C00009385	0 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00009385	5 / 3
P18054	Arachidonate 12-lipoxygenase, 12S-type	Enzyme	C00009385	2 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00002507	0 / 0
P03372	Estrogen receptor	NR3A1	C00009392	1 / 1
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00009385	0 / 0
Q07869	Peroxisome proliferator-activated receptor alpha	NR1C1	C00009385	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00002507	1 / 0

41 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00002507
19	ABCA1, ABC-1, ABC1, CERP, HDLDT1, TGD	ATP-binding cassette, sub-family A (ABC1), member 1	C00009392
119	ADD2, ADDB	adducin 2 (beta)	C00009392
396	ARHGDIA, GDIA1, NPHS8, RHOGDI, RHOGDI-1	Rho GDP dissociation inhibitor (GDI) alpha	C00009392
23545	ATP6V0A2, A2, ARCL, ARCL2A, ATP6A2, ATP6N1D, J6B7, RTF, STV1, TJ6, TJ6M, TJ6S, VPH1, WSS	ATPase, H+ transporting, lysosomal V0 subunit a2 (EC:3.6.3.6)	C00009392
11177	BAZ1A, ACF1, WALp1, WCRF180, hACF1	bromodomain adjacent to zinc finger domain, 1A	C00009392
890	CCNA2, CCN1, CCNA	cyclin A2	C00009392
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00009392
1019	CDK4, CMM3, PSK-J3	cyclin-dependent kinase 4 (EC:2.7.11.22)	C00009392
1026	CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1	cyclin-dependent kinase inhibitor 1A (p21, Cip1)	C00009392
1795	DOCK3, MOCA, PBP	dedicator of cytokinesis 3	C00009392
2041	EPHA1, EPH, EPHT, EPHT1	EPH receptor A1 (EC:2.7.10.1)	C00009392
83715	ESPN, DFNB36	espin	C00009392
2099	ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1	estrogen receptor 1	C00009392
2100	ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2	estrogen receptor 2 (ER beta)	C00009392
56776	FMN2	formin 2	C00009392
7866	IFRD2, IFNRP, SKMc15, SM15	interferon-related developmental regulator 2	C00009392
26145	IRF2BP1	interferon regulatory factor 2 binding protein 1	C00009392
3725	JUN, AP-1, AP1, c-Jun	jun proto-oncogene	C00009392
26251	KCNG2, KCNF2, KV6.2	potassium voltage-gated channel, subfamily G, member 2	C00009392
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00009392
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00009392
4314	MMP3, CHDS6, MMP-3, SL-1, STMY, STMY1, STR1	matrix metallopeptidase 3 (stromelysin 1, progelatinase) (EC:3.4.24.17)	C00009392
4318	MMP9, CLG4B, GELB, MANDP2, MMP-9	matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35)	C00009392
8204	NRIP1, RIP140	nuclear receptor interacting protein 1	C00009392
56944	OLFML3, HNOEL-iso, OLF44	olfactomedin-like 3	C00009392
5111	PCNA	proliferating cell nuclear antigen	C00009392
64236	PDLIM2, MYSTIQUE, SLIM	PDZ and LIM domain 2 (mystique)	C00009392
5411	PNN, DRS, DRSP, SDK3, memA	pinin, desmosome associated protein	C00009392
5458	POU4F2, BRN3.2, BRN3B, Brn-3b	POU class 4 homeobox 2	C00009392
6197	RPS6KA3, CLS, HU-3, ISPK-1, MAPKAPK1B, MRX19, RSK, RSK2, S6K-alpha3, p90-RSK2, pp90RSK2	ribosomal protein S6 kinase, 90kDa, polypeptide 3 (EC:2.7.11.1)	C00009392
81537	SGPP1, SPPase1	sphingosine-1-phosphate phosphatase 1	C00009392
6558	SLC12A2, BSC, BSC2, NKCC1	solute carrier family 12 (sodium/potassium/chloride transporter), member 2	C00009392
6667	SP1	Sp1 transcription factor	C00009392
6781	STC1, STC	stanniocalcin 1	C00009392
6870	TACR3, HH11, NK-3R, NK3R, NKR, TAC3RL	tachykinin receptor 3	C00009392
7130	TNFAIP6, TSG-6, TSG6	tumor necrosis factor, alpha-induced protein 6	C00009392
7157	TP53, BCC7, LFS1, P53, TRP53	tumor protein p53	C00009392
9537	TP53I11, PIG11	tumor protein p53 inducible protein 11	C00009392
7345	UCHL1, NDGOA, PARK5, PGP_9.5, PGP9.5, PGP95, Uch-L1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) (EC:3.4.19.12)	C00009392
7421	VDR, NR1I1	vitamin D (1,25- dihydroxyvitamin D3) receptor	C00009392

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions