Species

KNApSAcK Entry

Organism name Machaerium mucronulatum
Genus Machaerium
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Fabaceae
Linked NCBI taxonomy ID 3803
Linked level family

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00009389 External link 512 Cyclosin
/ Calycosin
/ 3'-Hydroxyformononetin
CHEMBL241608
10 / 9 / 6 No. 3 No. 15
C00009628 External link 512 Mucronucarpan
/ 2,10-Dihydroxy-3,9-dimethoxypterocarpan
No. 66 No. 15
C00002551 External link 512 (-)-Mucronulatol
CHEMBL253474
CHEMBL478971
CHEMBL1087024
5 / 1 / 0 No. 73 No. 15
C00020688 External link 512 (+)-Mucronulatol
/ (R)-Mucronulatol
CHEMBL253474
CHEMBL478971
CHEMBL1087024
5 / 1 / 0 No. 73 No. 15
C00020656 External link 512 Mucronulastyrene
No. 379
C00020657 External link 512 Mucronustyrene
CHEMBL387819
No. 379
C00020658 External link 512 (-)-Mucroquinone
No. 517
C00009743 External link 512 (3R)-Mucroquinone
/ 7-Hydroxy-8,4'-dimethoxyisoflavanquinone
No. 517

Human Protein / Gene in interactions

14 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9UNA4 DNA polymerase iota Enzyme C00002551 C00009389 C00020688 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00002551 C00020688 1 / 0
O75496 Geminin Unclassified protein C00002551 C00020688 0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00002551 C00020688 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00002551 C00020688 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00009389 0 / 0
O15118 Niemann-Pick C1 protein Unclassified protein C00009389 1 / 1
P38398 Breast cancer type 1 susceptibility protein Enzyme C00009389 4 / 2
P51151 Ras-related protein Rab-9A Unclassified protein C00009389 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00009389 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00009389 4 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00009389 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00009389 0 / 0
P06746 DNA polymerase beta Enzyme C00009389 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (10)

OMIM preferred title UniProt
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#257220 Niemann-pick disease, type c1; npc1 O15118
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (6)

KEGG name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00027 Ovarian cancer P38398 (related)
H00031 Breast cancer P38398 (related)