| Organism name | Sophora fraseri |
|---|---|
| Genus | Sophora |
| Family | Fabaceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Sophora |
|---|---|
| Linked NCBI taxonomy ID | 3896 |
| Linked level | genus |
| Family in NCBI taxonomy | Fabaceae |
|---|---|
| ID | 3803 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | rosids |
|---|---|
| ID | 71275 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00009389
|
Cyclosin
/ Calycosin / 3'-Hydroxyformononetin |
CHEMBL241608
|
10 / 9 / 6 | No. 3 | No. 15 |
|
||
|
C00009802
|
2-(2,4-Dihydroxyphenyl)-5,6-methylenedioxybenzofuran
/ 2',4'-Dihydroxy-5,6-methylenedioxy-2-phenylbenzofuran |
CHEMBL524490
|
No. 27 | No. 15 |
|
|||
|
C00002573
|
Sophoraisoflavanone A
|
No. 28 | No. 14 |
|
||||
|
C00019631
|
Fraserinone A
/ 5,7,4'-Trihydroxy-2'-methoxy-5'-(1,1-dimethyl-2-propenyl)isoflavanone |
No. 28 | No. 14 |
|
||||
|
C00009973
|
Sophoronol
/ 3,5,7-Trihydroxy-2'-methoxy-6'',6''-dimethylpyrano[2'',3'':4',3']isoflavanone |
CHEMBL550446
|
No. 127 | No. 14 |
|
|||
|
C00010011
|
Sophoracarpan B
/ 6-Methoxymaackiain / (6R,6aS,11aR)-3-Hydroxy-6-methoxy-8,9-methylenedioxypterocarpan |
No. 1655 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P06746 | DNA polymerase beta | Enzyme | C00009389 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00009389 | 0 / 0 |
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00009389 | 4 / 2 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00009389 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00009389 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00009389 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00009389 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00009389 | 4 / 3 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00009389 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00009389 | 0 / 0 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #114480 | Breast cancer |
P38398
|
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 |
P38398
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #167000 | Ovarian cancer |
P38398
|
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 |
P38398
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| KEGG | name | UniProt |
|---|---|---|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00027 | Ovarian cancer |
P38398
(related)
|
| H00031 | Breast cancer |
P38398
(related)
|