Species

KNApSAcK Entry

Organism name Tephrosia obovata
Genus Tephrosia
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Tephrosia obovata
Linked NCBI taxonomy ID 185973
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00008431 External link 512 Obovatin
CHEMBL1689204
No. 127 No. 14
C00007084 External link 512 Pongachalcone I
No. 130
C00002580 External link 512 Toxicarol
/ Toxicarin
/ alpha-Toxicarol
CHEMBL508992
CHEMBL1488225
10 / 9 / 6 No. 589 No. 15

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein C00002580 4 / 1
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00002580 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002580 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00002580 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00002580 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00002580 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002580 0 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00002580 4 / 3
B2RXH2 Lysine-specific demethylase 4E Enzyme C00002580 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00002580 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#600274 Frontotemporal dementia; ftd P10636
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (6)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)