Species

KNApSAcK Entry

Organism name Gynura elliptica
Genus Gynura
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Gynura
Linked NCBI taxonomy ID 109564
Linked level genus

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (4)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00007558 External link 512 Syringaldehyde
/ 4-Hydroxy-3,5-dimethoxybenzaldehyde
CHEMBL225303
C069665
No. 856
C00002683 External link 512 Vanillin
CHEMBL13883
18 / 8 / 9 No. 1003
C00036621 External link 512 6-Hydroxy-2,2-dimethylchroman-4-one
CHEMBL1384267
3 / 11 / 6 No. 2514
C00036310 External link 512 (+)-Gynunone
No. 7066

Human Protein / Gene in interactions

21 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9HAW8 UDP-glucuronosyltransferase 1-10 Enzyme C00002683 0 / 0
P78527 DNA-dependent protein kinase catalytic subunit Atypical serine/threonine protein kinase PIKK subfamily C00002683 0 / 0
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00002683 0 / 0
P51649 Succinate-semialdehyde dehydrogenase, mitochondrial Oxidoreductase C00002683 1 / 1
P34969 5-hydroxytryptamine receptor 7 Serotonin receptor C00002683 0 / 0
Q9HAW7 UDP-glucuronosyltransferase 1-7 Enzyme C00002683 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00002683 0 / 0
O60656 UDP-glucuronosyltransferase 1-9 Enzyme C00002683 0 / 0
O00519 Fatty-acid amide hydrolase 1 Enzyme C00002683 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00036621 7 / 3
P83916 Chromobox protein homolog 1 Unclassified protein C00036621 0 / 0
P80404 4-aminobutyrate aminotransferase, mitochondrial Transferase C00002683 1 / 1
Q96RI1 Bile acid receptor NR1H4 C00002683 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00002683 2 / 2
Q9Y4X1 UDP-glucuronosyltransferase 2A1 Enzyme C00002683 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00036621 4 / 3
P19224 UDP-glucuronosyltransferase 1-6 Enzyme C00002683 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00002683 0 / 0
P10275 Androgen receptor NR3C4 C00002683 3 / 4
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00002683 1 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00002683 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (19)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#119900 Digital clubbing, isolated congenital P15428
#600274 Frontotemporal dementia; ftd P10636
#613163 Gaba-transaminase deficiency P80404
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#271980 Succinic semialdehyde dehydrogenase deficiency; ssadhd P51649
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (15)

KEGG name UniProt
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00835 Succinic semialdehyde dehydrogenase (SSADH) deficiency P51649 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H01257 GABA-transaminase deficiency P80404 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)