Species

KNApSAcK Entry

Organism name Echinacea angustifolia
Genus Echinacea
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Echinacea angustifolia
Linked NCBI taxonomy ID 308558
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002738 External link 512 Echinacoside
CHEMBL393090
CHEMBL510539
C060297
6 / 3 / 4 3 / 1 No. 33

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P00352 Retinal dehydrogenase 1 Enzyme C00002738 0 / 0
P10145 Interleukin-8 Secreted protein C00002738 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00002738 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00002738 3 / 3
P16050 Arachidonate 15-lipoxygenase Enzyme C00002738 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002738 0 / 1

3 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
571 BACH1, BACH-1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 C00002738
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00002738
4780 NFE2L2, NRF2 nuclear factor, erythroid 2-like 2 C00002738

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714

KEGG DISEASE (4)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D008107 Liver Diseases C00002738