Species

KNApSAcK Entry

Organism name Pluchea sagittalis
Genus Pluchea
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Pluchea sagittalis
Linked NCBI taxonomy ID 175519
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Natural Activity

List (15)

Species Activity
Pluchea sagittalis (Lam.) Cabrera Antiedemic
Pluchea sagittalis (Lam.) Cabrera Antihysteric
Pluchea sagittalis (Lam.) Cabrera Antiinflammatory
Pluchea sagittalis (Lam.) Cabrera Antioxidant
Pluchea sagittalis (Lam.) Cabrera Antiradicular
Pluchea sagittalis (Lam.) Cabrera Antiseptic
Pluchea sagittalis (Lam.) Cabrera Aperitive
Pluchea sagittalis (Lam.) Cabrera Carminative
Pluchea sagittalis (Lam.) Cabrera Eupeptic
Pluchea sagittalis (Lam.) Cabrera Febrifuge
Pluchea sagittalis (Lam.) Cabrera Hepatotonic
Pluchea sagittalis (Lam.) Cabrera Sedative
Pluchea sagittalis (Lam.) Cabrera Stimulant
Pluchea sagittalis (Lam.) Cabrera Stomachic
Pluchea sagittalis (Lam.) Cabrera Tonic

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00004789 External link 512 5,7,3',4'-Tetrahydroxy-3,6,8-trimethoxyflavone
/ 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3,6,8-trimethoxy-4H-1-benzopyran-4-one
CHEMBL307373
No. 3 No. 15
C00004694 External link 512 Centaureidin
/ Desmethoxycentaureidine
/ Quercetagetin 3,4',6-trimethyl ether
/ 5,7,3'-Trihydroxy-3,6,4'-trimethoxyflavone
/ 5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6-dimethoxy-4H-1-benzopyran-4-one
CHEMBL77552
C083161
24 / 14 / 6 No. 3 No. 15
C00002751 External link 512 Isochlorogenic acid b
/ 3,4-Dicaffeoylquinic acid
CHEMBL358821
CHEMBL149674
CHEMBL177126
CHEMBL249448
CHEMBL453276
CHEMBL453537
CHEMBL1972460
2 / 0 / 0 No. 518 No. 6

Human Protein / Gene in interactions

26 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00004694 1 / 1
O60218 Aldo-keto reductase family 1 member B10 Enzyme C00002751 0 / 0
P39748 Flap endonuclease 1 Enzyme C00004694 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00004694 2 / 0
O75496 Geminin Unclassified protein C00004694 0 / 0
P15121 Aldose reductase Enzyme C00002751 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00004694 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00004694 1 / 1
P51843 Nuclear receptor subfamily 0 group B member 1 Nuclear hormone receptor subfamily 0 group B member 1 C00004694 2 / 2
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00004694 1 / 0
Q13748 Tubulin alpha-3C/D chain Structural C00004694 0 / 0
P68366 Tubulin alpha-4A chain Structural C00004694 0 / 0
Q9H4B7 Tubulin beta-1 chain Structural C00004694 1 / 0
P04350 Tubulin beta-4A chain Structural C00004694 2 / 0
Q3ZCM7 Tubulin beta-8 chain Structural C00004694 0 / 0
P07437 Tubulin beta chain Structural C00004694 0 / 0
Q71U36 Tubulin alpha-1A chain Structural C00004694 1 / 1
P68371 Tubulin beta-4B chain Structural C00004694 0 / 0
Q13509 Tubulin beta-3 chain Structural C00004694 2 / 1
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00004694 0 / 0
P68363 Tubulin alpha-1B chain Unclassified protein C00004694 0 / 0
Q13885 Tubulin beta-2A chain Structural C00004694 0 / 0
Q6PEY2 Tubulin alpha-3E chain Unclassified protein C00004694 0 / 0
Q9BQE3 Tubulin alpha-1C chain Unclassified protein C00004694 0 / 0
Q9BUF5 Tubulin beta-6 chain Structural C00004694 0 / 0
Q9BVA1 Tubulin beta-2B chain Structural C00004694 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#300018 46,xy sex reversal 2; srxy2 P51843
#300200 Adrenal hypoplasia, congenital; ahc P51843
#114500 Colorectal cancer; crc P84022
#614039 Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 Q13509
#128101 Dystonia 4, torsion, autosomal dominant; dyt4 P04350
#600638 Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a Q13509
#137800 Glioma susceptibility 1; glm1 O75874
#612438 Leukodystrophy, hypomyelinating, 6; hld6 P04350
#611603 Lissencephaly 3; lis3 Q71U36
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#613112 Macrothrombocytopenia, autosomal dominant, tubb1-related Q9H4B7
#610031 Polymicrogyria, symmetric or asymmetric; pmgysa Q9BVA1
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (6)

KEGG name UniProt
H00552 Glycerol kinase deficiency (GKD) P51843 (related)
H00607 46,XY disorders of sex development (Disorders of gonadal development) P51843 (related)
H00838 Congenital fibrosis of the extraocular muscles (CFEOM) Q13509 (related)
H00268 Lissencephaly (LIS) Q71U36 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)