| Organism name | Frullania tamarisci | 
|---|---|
| Genus | Frullania | 
| Family | Jubulaceae | 
| Kingdom | Plantae | 
| Linked NCBI taxonomy name | Frullania tamarisci | 
|---|---|
| Linked NCBI taxonomy ID | 95764 | 
| Linked level | species | 
| Family in NCBI taxonomy | Frullaniaceae | 
|---|---|
| ID | 400721 | 
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae | 
|---|---|
| ID | 33090 | 
| Plant class | Embryophyta | 
|---|---|
| ID | 3193 | 
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | KCF-S cluster | phytochemical cluster | figure | 
|---|---|---|---|---|---|---|---|---|
| C00014074   | 6-C-Rhamnopyranosylrhamnetin 3-O-glucopyranoside | No. 1 | No. 15 |   | ||||
| C00004266   | Cinaroside / Luteolin 7-glucoside / Luteolin-7-O-glucoside / Luteolin 7-O-beta-D-glucopyranoside | CHEMBL233929 CHEMBL574683 CHEMBL1159535 CHEMBL1317166 | C066408 | 26 / 31 / 53 | No. 2 | No. 15 |   | |
| C00003242   | (+)-beta-Cyclocostunolide / beta-Cyclocostunolide[3aS-(3aalpha,5abeta,9aalpha,9bbeta)]-Decahydro-5a-methyl-3,9-bis(methylene)-naphtho[1,2-b]furan-2(3H)-one | No. 69 | No. 38 |   | ||||
| C00003241   | alpha-Cyclocostunolide | CHEMBL218788 | C002603 | No. 69 | No. 38 |   | ||
| C00015321   | 3,4'-Dimethoxybibenzyl / Lunularine dimethyl ether | CHEMBL477915 | No. 96 | No. 26 |   | |||
| C00016975   | Eremophilene | No. 151 | No. 38 |   | ||||
| C00013031   | (+)-Frullanolide / [3aR-(3aalpha,5abeta,9balpha)]-3a,4,5,5a,6,7,8,9b-Octahydro-5a,9-dimethyl-3-methylenenaphtho[1,2-b]furan-2(3H)-one | No. 178 | No. 38 |   | ||||
| C00003287   | (-)-Frullanolide / Tournefortiolide / [3aS-(3aalpha,5abeta,9balpha)]-3a,4,5,5a,6,7,8,9b-Octahydro-5a,9-dimethyl-3-methylenenaphtho[1,2-b]furan-2(3H)-one | C007787 | No. 178 | No. 38 |   | |||
| C00003161   | Ledol / (+)-Ledol | CHEMBL2171207 | 1 / 2 / 3 | No. 197 | No. 38 |   | ||
| C00021213   | Globulol / (-)-Globulol | CHEMBL2171207 | 1 / 2 / 3 | No. 197 | No. 38 |   | ||
| C00020066   | T-Cadinol / epi-alpha-Cadinol | CHEMBL486795 | C072576 | No. 205 | No. 38 |   | ||
| C00002889   | Lunularin / 3,4'-Dihydroxybibenzyl | CHEMBL445252 | C121619 | No. 242 | No. 26 |   | ||
| C00003118   | Copaene / alpha-Copaene / (-)-alpha-Copaene | No. 333 | No. 38 |   | ||||
| C00021886   | beta-Pompene / Gymnomitrene / beta-Barbatene / beta-Gymnomitrene | No. 365 | No. 38 |   | ||||
| C00012810   | Rosifoliol / (+)-Rosifoliol / [2R-(2alpha,4abeta,8beta)]-2,3,4,4a,5,6,7,8-octahydro-alpha,alpha,4a,8-tetramethyl-2-naphthalenemethanol | No. 613 | No. 38 |   | ||||
| C00036399   | 11-Bourbonene | No. 640 |   | |||||
| C00036290   | (-)-Tamariscene | No. 640 |   | |||||
| C00036308   | (+)-Germacrene A | No. 701 | No. 38 |   | ||||
| C00037126   | Eudesma-4,11-diene / (+)-Selina-4,11-diene | No. 748 |   | |||||
| C00036286   | (-)-Pacifigorgia-1(9),10-diene | No. 1391 |   | |||||
| C00036271   | (-)-beta-Elemene | CHEMBL448502 CHEMBL479707 | No. 1400 |   | ||||
| C00036291   | (-)-Tamariscol | No. 2857 |   | |||||
| C00021436   | Tamariscol | No. 2857 |   | |||||
| C00020383   | gamma-Gurjunene / (+)-gamma-Gurjunene | CHEMBL455046 | No. 3712 | No. 38 |   | |||
| C00036285   | (-)-Pacifigorgia-1(6),10-diene | No. 8531 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| P08581 | Hepatocyte growth factor receptor | TK tyrosine-protein kinase MET subfamily | C00003161 C00021213 | 2 / 3 | 
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00004266 | 0 / 0 | 
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00004266 | 0 / 0 | 
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00004266 | 0 / 0 | 
| P39748 | Flap endonuclease 1 | Enzyme | C00004266 | 0 / 0 | 
| O75496 | Geminin | Unclassified protein | C00004266 | 0 / 0 | 
| P38398 | Breast cancer type 1 susceptibility protein | Enzyme | C00004266 | 4 / 2 | 
| Q9Y253 | DNA polymerase eta | Enzyme | C00004266 | 1 / 1 | 
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00004266 | 0 / 0 | 
| P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00004266 | 0 / 0 | 
| P14679 | Tyrosinase | Oxidoreductase | C00004266 | 4 / 2 | 
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00004266 | 7 / 37 | 
| Q99714 | 3-hydroxyacyl-CoA dehydrogenase type-2 | Enzyme | C00004266 | 3 / 3 | 
| Q99700 | Ataxin-2 | Unclassified protein | C00004266 | 1 / 1 | 
| Q9UNA4 | DNA polymerase iota | Enzyme | C00004266 | 0 / 0 | 
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00004266 | 0 / 0 | 
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00004266 | 0 / 0 | 
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00004266 | 4 / 3 | 
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00004266 | 0 / 0 | 
| P24298 | Alanine aminotransferase 1 | Enzyme | C00004266 | 0 / 0 | 
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00004266 | 0 / 0 | 
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00004266 | 0 / 0 | 
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00004266 | 1 / 1 | 
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00004266 | 1 / 0 | 
| O00255 | Menin | Unclassified protein | C00004266 | 2 / 5 | 
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00004266 | 1 / 2 | 
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00004266 | 2 / 1 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #300438 | 17-beta-hydroxysteroid dehydrogenase x deficiency | Q99714 | 
| #202300 | Adrenocortical carcinoma, hereditary; adcc | P04637 | 
| #103470 | Albinism, ocular, with sensorineural deafness | P14679 | 
| #203100 | Albinism, oculocutaneous, type ia; oca1a | P14679 | 
| #606952 | Albinism, oculocutaneous, type ib; oca1b | P14679 | 
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 | P04637 | 
| #114480 | Breast cancer | P38398 | 
| #604370 | Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 | P38398 | 
| #114500 | Colorectal cancer; crc | Q14191 | 
| #133239 | Esophageal cancer | P04637 | 
| #600274 | Frontotemporal dementia; ftd | P10636 | 
| #137800 | Glioma susceptibility 1; glm1 | O75874 | 
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay | Q03164 | 
| #114550 | Hepatocellular carcinoma | P08581 | 
| #145000 | Hyperparathyroidism 1; hrpt1 | O00255 | 
| #151623 | Li-fraumeni syndrome 1; lfs1 | P04637 | 
| #211980 | Lung cancer | P04637 | 
| #300705 | Mental retardation, x-linked 17; mrx17 | Q99714 | 
| #300220 | Mental retardation, x-linked, syndromic 10; mrxs10 | Q99714 | 
| #131100 | Multiple endocrine neoplasia, type i; men1 | O00255 | 
| #167000 | Ovarian cancer | P38398 | 
| #614320 | Pancreatic cancer, susceptibility to, 4; pnca4 | P38398 | 
| #260500 | Papilloma of choroid plexus; cpp | P04637 | 
| #260540 | Parkinson-dementia syndrome | P10636 | 
| #172700 | Pick disease of brain | P10636 | 
| #605074 | Renal cell carcinoma, papillary, 1; rccp1 | P08581 | 
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 | P14679 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 | Q9NUW8 | 
| #275355 | Squamous cell carcinoma, head and neck; hnscc | P04637 | 
| #601104 | Supranuclear palsy, progressive, 1; psnp1 | P10636 | 
| #277700 | Werner syndrome; wrn | Q14191 | 
| #278750 | Xeroderma pigmentosum, variant type; xpv | Q9Y253 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00033 | Adrenal carcinoma | O00255
                            (related) P04637 (related) | 
| H00034 | Carcinoid | O00255
                            (related) | 
| H00045 | Malignant islet cell carcinoma | O00255
                            (related) | 
| H00246 | Primary hyperparathyroidism | O00255
                            (related) | 
| H01102 | Pituitary adenomas | O00255
                            (related) | 
| H00004 | Chronic myeloid leukemia (CML) | P04637
                            (related) | 
| H00005 | Chronic lymphocytic leukemia (CLL) | P04637
                            (related) | 
| H00006 | Hairy-cell leukemia | P04637
                            (related) | 
| H00008 | Burkitt lymphoma | P04637
                            (related) | 
| H00009 | Adult T-cell leukemia | P04637
                            (related) | 
| H00010 | Multiple myeloma | P04637
                            (related) | 
| H00013 | Small cell lung cancer | P04637
                            (related) | 
| H00014 | Non-small cell lung cancer | P04637
                            (related) | 
| H00015 | Malignant pleural mesothelioma | P04637
                            (related) | 
| H00016 | Oral cancer | P04637
                            (related) P04637 (marker) | 
| H00017 | Esophageal cancer | P04637
                            (related) P04637 (marker) | 
| H00018 | Gastric cancer | P04637
                            (related) P08581 (related) | 
| H00019 | Pancreatic cancer | P04637
                            (related) P04637 (marker) | 
| H00020 | Colorectal cancer | P04637
                            (related) P04637 (marker) | 
| H00022 | Bladder cancer | P04637
                            (related) | 
| H00025 | Penile cancer | P04637
                            (related) P04637 (marker) | 
| H00026 | Endometrial Cancer | P04637
                            (related) | 
| H00027 | Ovarian cancer | P04637
                            (related) P38398 (related) | 
| H00028 | Choriocarcinoma | P04637
                            (related) | 
| H00029 | Vulvar cancer | P04637
                            (related) | 
| H00031 | Breast cancer | P04637
                            (related) P38398 (related) | 
| H00032 | Thyroid cancer | P04637
                            (related) | 
| H00036 | Osteosarcoma | P04637
                            (related) | 
| H00038 | Malignant melanoma | P04637
                            (related) P14679 (marker) | 
| H00039 | Basal cell carcinoma | P04637
                            (related) | 
| H00040 | Squamous cell carcinoma | P04637
                            (related) | 
| H00041 | Kaposi's sarcoma | P04637
                            (related) | 
| H00042 | Glioma | P04637
                            (related) P04637 (marker) | 
| H00044 | Cancer of the anal canal | P04637
                            (related) | 
| H00046 | Cholangiocarcinoma | P04637
                            (related) P08581 (related) | 
| H00047 | Gallbladder cancer | P04637
                            (related) | 
| H00048 | Hepatocellular carcinoma | P04637
                            (related) | 
| H00055 | Laryngeal cancer | P04637
                            (related) P04637 (marker) | 
| H00881 | Li-Fraumeni syndrome | P04637
                            (related) | 
| H01007 | Choroid plexus papilloma | P04637
                            (related) | 
| H00021 | Renal cell carcinoma | P04637
                            (marker) P08581 (related) | 
| H00058 | Amyotrophic lateral sclerosis (ALS) | P10636
                            (related) | 
| H00077 | Progressive supranuclear palsy (PSP) | P10636
                            (related) | 
| H00078 | Frontotemporal lobar degeneration (FTLD) | P10636
                            (related) | 
| H00168 | Oculocutaneous albinism (OCA) | P14679
                            (related) | 
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) | Q03164
                            (related) Q03164 (marker) | 
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) | Q03164
                            (related) | 
| H00296 | Defects in RecQ helicases | Q14191
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) Q9NUW8 (related) | 
| H00480 | Non-syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00658 | Syndromic X-linked mental retardation | Q99714
                            (related) | 
| H00925 | 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency | Q99714
                            (related) | 
| H00403 | Disorders of nucleotide excision repair | Q9Y253
                            (related) |