Species

KNApSAcK Entry

Organism name Rubus fruticosus
Genus Rubus
Family Rosaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Rubus fruticosus
Linked NCBI taxonomy ID 211815
Linked level species

Family

Family in NCBI taxonomy Rosaceae
ID 3745

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00002935 External link 512 Procyanidin B4
/ Catechin-(4alpha->8)-epicatechin
CHEMBL38714
CHEMBL81753
CHEMBL504937
CHEMBL501490
CHEMBL447373
CHEMBL1253314
CHEMBL1590914
20 / 7 / 8 No. 16 No. 19
C00009073 External link 512 Procyanidin B8
/ Catechin-(4alpha->6)-epicatechin
CHEMBL506487
CHEMBL502984
CHEMBL451115
No. 16 No. 19

Human Protein / Gene in interactions

20 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00002935 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00002935 0 / 1
P18433 Receptor-type tyrosine-protein phosphatase alpha Receptor tyrosine-protein phosphatase C00002935 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00002935 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00002935 3 / 3
P23467 Receptor-type tyrosine-protein phosphatase beta Receptor tyrosine-protein phosphatase C00002935 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00002935 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00002935 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00002935 0 / 1
Q05513 Protein kinase C zeta type Iota C00002935 0 / 0
Q04759 Protein kinase C theta type Delta C00002935 0 / 1
Q02156 Protein kinase C epsilon type Eta C00002935 0 / 0
O94806 Serine/threonine-protein kinase D3 Pkd C00002935 0 / 0
P17252 Protein kinase C alpha type Alpha C00002935 0 / 0
Q05655 Protein kinase C delta type Delta C00002935 0 / 0
P05129 Protein kinase C gamma type Alpha C00002935 1 / 1
P05771 Protein kinase C beta type Alpha C00002935 0 / 0
P24723 Protein kinase C eta type Eta C00002935 1 / 0
P41743 Protein kinase C iota type Iota C00002935 0 / 0
Q15139 Serine/threonine-protein kinase D1 Pkd C00002935 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#605361 Spinocerebellar ataxia 14; sca14 P05129
#601367 Stroke, ischemic P24723

KEGG DISEASE (8)

KEGG name UniProt
H00063 Spinocerebellar ataxia (SCA) P05129 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00408 Type I diabetes mellitus Q04759 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)