Species

KNApSAcK Entry

Organism name Iris nigricans
Genus Iris
Family Iridaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Iris nigricans
Linked NCBI taxonomy ID 995810
Linked level species

Family

Family in NCBI taxonomy Iridaceae
ID 26339

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00036390 External link 512 1,6-Dihydroxy-3,7-dimethoxyxanthone
No. 3 No. 15
C00002968 External link 512 Norathyriol
/ 1,3,6,7-Tetrahydroxyxanthoene
CHEMBL187265
C069053
9 / 10 / 7 4 / 0 No. 71 No. 15
C00002946 External link 512 Demethylbellidifolin
/ 1,3,5,8-Tetrahdroxyyxanthone
CHEMBL184574
5 / 2 / 1 No. 71 No. 15

Human Protein / Gene in interactions

13 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00002946 C00002968 1 / 1
Q15078 Cyclin-dependent kinase 5 activator 1 REG serine/threonine protein kinase family C00002946 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00002968 2 / 2
P27338 Amine oxidase [flavin-containing] B Oxidoreductase C00002946 0 / 0
P49327 Fatty acid synthase Transferase C00002968 0 / 0
Q00535 Cyclin-dependent kinase 5 Cdk5 C00002946 0 / 0
P39900 Macrophage metalloelastase M10A C00002968 0 / 0
P03956 Interstitial collagenase M10A C00002968 0 / 1
P45452 Collagenase 3 M10A C00002968 1 / 1
P08253 72 kDa type IV collagenase M10A C00002968 1 / 3
P12821 Angiotensin-converting enzyme M2 C00002968 4 / 2
P22303 Acetylcholinesterase Hydrolase C00002946 1 / 0
P08254 Stromelysin-1 M10A C00002968 1 / 0

4 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
5243 ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) C00002968
5465 PPARA, NR1C1, PPAR, PPARalpha, hPPAR peroxisome proliferator-activated receptor alpha C00002968
5467 PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB peroxisome proliferator-activated receptor delta C00002968
5468 PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma peroxisome proliferator-activated receptor gamma C00002968

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (11)

OMIM preferred title UniProt
#300615 Brunner syndrome P21397
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#614519 Hemorrhage, intracerebral, susceptibility to; ich P12821
#603932 Intervertebral disc disease; idd P14780
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#612624 Microvascular complications of diabetes, susceptibility to, 3; mvcd3 P12821
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#267430 Renal tubular dysgenesis; rtd P12821
#602111 Spondyloepimetaphyseal dysplasia, missouri type P45452
#601367 Stroke, ischemic P12821
#112100 Yt blood group antigen P22303

KEGG DISEASE (7)

KEGG name UniProt
H00028 Choriocarcinoma P03956 (related)
P08253 (related)
H00025 Penile cancer P08253 (related)
P14780 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00083 Allograft rejection P12821 (related)
H00575 Renal tubular dysgenesis P12821 (related)
H00479 Metaphyseal dysplasias P14780 (related)
P45452 (related)
H00548 Brunner syndrome P21397 (related)