Pentaphalangium solomonse
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00002968
|
Norathyriol
/ 1,3,6,7-Tetrahydroxyxanthoene |
CHEMBL187265
|
C069053
|
9 / 10 / 7 | 4 / 0 | No. 71 | No. 15 |
|
Human Protein / Gene in interactions
9 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P39900 | Macrophage metalloelastase | M10A | C00002968 | 0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | C00002968 | 2 / 2 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00002968 | 1 / 1 |
| P49327 | Fatty acid synthase | Transferase | C00002968 | 0 / 0 |
| P03956 | Interstitial collagenase | M10A | C00002968 | 0 / 1 |
| P45452 | Collagenase 3 | M10A | C00002968 | 1 / 1 |
| P08253 | 72 kDa type IV collagenase | M10A | C00002968 | 1 / 3 |
| P12821 | Angiotensin-converting enzyme | M2 | C00002968 | 4 / 2 |
| P08254 | Stromelysin-1 | M10A | C00002968 | 1 / 0 |
4 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00002968
|
| 5465 | PPARA, NR1C1, PPAR, PPARalpha, hPPAR | peroxisome proliferator-activated receptor alpha |
C00002968
|
| 5467 | PPARD, FAAR, NR1C2, NUC1, NUCI, NUCII, PPARB | peroxisome proliferator-activated receptor delta |
C00002968
|
| 5468 | PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma | peroxisome proliferator-activated receptor gamma |
C00002968
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (10)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300615 | Brunner syndrome |
P21397
|
| #614466 | Coronary heart disease, susceptibility to, 6; chds6 |
P08254
|
| #614519 | Hemorrhage, intracerebral, susceptibility to; ich |
P12821
|
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #612624 | Microvascular complications of diabetes, susceptibility to, 3; mvcd3 |
P12821
|
| #259600 | Multicentric osteolysis, nodulosis, and arthropathy; mona |
P08253
|
| #267430 | Renal tubular dysgenesis; rtd |
P12821
|
| #602111 | Spondyloepimetaphyseal dysplasia, missouri type |
P45452
|
| #601367 | Stroke, ischemic |
P12821
|
KEGG DISEASE (7)
| KEGG | name | UniProt |
|---|---|---|
| H00028 | Choriocarcinoma |
P03956
(related)
P08253 (related) |
| H00025 | Penile cancer |
P08253
(related)
P14780 (related) |
| H00472 | Torg-Winchester syndrome |
P08253
(related)
|
| H00083 | Allograft rejection |
P12821
(related)
|
| H00575 | Renal tubular dysgenesis |
P12821
(related)
|
| H00479 | Metaphyseal dysplasias |
P14780
(related)
P45452 (related) |
| H00548 | Brunner syndrome |
P21397
(related)
|