Species

KNApSAcK Entry

Organism name Polyalthia crassa
Genus Polyalthia
Family Annonaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Marsypopetalum crassum
Linked NCBI taxonomy ID 1052074
Linked level species

Family

Family in NCBI taxonomy Annonaceae
ID 22140

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00027121 External link 512 Aristolactam AII
/ Aristololactam A II
CHEMBL390368
No. 125
C00029961 External link 512 Cinnamic acid
/ .beta-Phenylacrylic acid
CHEMBL27246
C029010
5 / 2 / 2 16 / 2 No. 904 No. 6
C00037209 External link 512 Goniofufurone
/ (+)-Goniofufurone
CHEMBL449995
CHEMBL491223
CHEMBL1171386
No. 960
C00041225 External link 512 (+)-Goniopypyrone
C080434
No. 960
C00002992 External link 512 Altholactone
/ Goniothalenol
/ (+)-Altholactone
CHEMBL512401
CHEMBL599777
CHEMBL1968763
No. 3082

Human Protein / Gene in interactions

5 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00029961 0 / 0
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00029961 1 / 1
Q8TDS4 Hydroxycarboxylic acid receptor 2 Hydroxycarboxylic acid receptor C00029961 0 / 0
P15121 Aldose reductase Enzyme C00029961 0 / 0
P03372 Estrogen receptor NR3A1 C00029961 1 / 1

16 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1586 CYP17A1, CPT7, CYP17, P450C17, S17AH cytochrome P450, family 17, subfamily A, polypeptide 1 (EC:1.14.99.9 4.1.2.30) C00029961
1548 CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) C00029961
1557 CYP2C19, CPCJ, CYP2C, P450C2C, P450IIC19 cytochrome P450, family 2, subfamily C, polypeptide 19 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00029961
1558 CYP2C8, CPC8, CYPIIC8, MP-12/MP-20 cytochrome P450, family 2, subfamily C, polypeptide 8 (EC:1.14.14.1) C00029961
1559 CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00029961
1565 CYP2D6, CPD6, CYP2D, CYP2D7AP, CYP2D7BP, CYP2D7P2, CYP2D8P2, CYP2DL1, CYPIID6, P450-DB1, P450C2D, P450DB1 cytochrome P450, family 2, subfamily D, polypeptide 6 (EC:1.14.14.1) C00029961
1571 CYP2E1, CPE1, CYP2E, P450-J, P450C2E cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) C00029961
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00029961
338442 HCAR2, GPR109A, HCA2, HM74a, HM74b, NIACR1, PUMAG, Puma-g hydroxycarboxylic acid receptor 2 C00029961
3284 HSD3B2, HSD3B, HSDB, SDR11E2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 (EC:1.1.1.145 5.3.3.1) C00029961
4846 NOS3, ECNOS, eNOS nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) C00029961
7299 TYR, ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3 tyrosinase (EC:1.14.18.1) C00029961
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00029961
54659 UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17) C00029961
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00029961
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00029961

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#615363 Estrogen resistance; estrr P03372
#278300 Xanthinuria, type i P47989

KEGG DISEASE (2)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
H00192 Xanthinuria P47989 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003384 Coxsackievirus Infections C00029961
D008545 Melanoma C00029961