Species

KNApSAcK Entry

Organism name Paeonia chinensis
Genus Paeonia
Family Paeoniaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Paeonia
Linked NCBI taxonomy ID 13625
Linked level genus

Family

Family in NCBI taxonomy Paeoniaceae
ID 24943

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003011 External link 512 Paeoniflorin
CHEMBL1078549
CHEMBL1397567
CHEMBL1972762
C015423
4 / 4 / 8 3 / 2 No. 1566

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P00352 Retinal dehydrogenase 1 Enzyme C00003011 0 / 0
P03372 Estrogen receptor NR3A1 C00003011 1 / 1
O00255 Menin Unclassified protein C00003011 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00003011 1 / 2

3 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
664 BNIP3, NIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 C00003011
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00003011
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00003011

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#615363 Estrogen resistance; estrr P03372
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255

KEGG DISEASE (8)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00026 Endometrial Cancer P03372 (marker)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D000647 Amnesia C00003011
D007022 Hypotension C00003011