Species

KNApSAcK Entry

Organism name Gibberella zeae
Genus Gibberella
Family Nectriaceae
Kingdom Fungi

NCBI taxonomy

Entry

Linked NCBI taxonomy name Fusarium graminearum
Linked NCBI taxonomy ID 5518
Linked level species

Family

Family in NCBI taxonomy Nectriaceae
ID 110618

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Fungi
ID 4751

Plant class

Plant class
ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003025 External link 512 Zearalenone
CHEMBL454173
CHEMBL1330445
CHEMBL1397216
D015025
48 / 50 / 70 163 / 5 No. 790

Human Protein / Gene in interactions

48 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P04637 Cellular tumor antigen p53 Transcription Factor C00003025 7 / 37
Q9P1W9 Serine/threonine-protein kinase pim-2 Pim C00003025 0 / 0
Q14289 Protein-tyrosine kinase 2-beta Fak C00003025 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00003025 4 / 1
Q99700 Ataxin-2 Unclassified protein C00003025 1 / 1
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00003025 2 / 2
Q15759 Mitogen-activated protein kinase 11 p38 C00003025 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00003025 1 / 1
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00003025 0 / 0
Q9H2G2 STE20-like serine/threonine-protein kinase STE serine/threonine protein kinase SLK subfamily C00003025 0 / 0
Q16659 Mitogen-activated protein kinase 6 CMGC serine/threonine protein kinase ERK3 subfamily C00003025 0 / 0
P02545 Prelamin-A/C Unclassified protein C00003025 11 / 10
P16473 Thyrotropin receptor Glycohormone receptor C00003025 3 / 2
P10828 Thyroid hormone receptor beta NR1A2 C00003025 3 / 1
P19793 Retinoic acid receptor RXR-alpha NR2B1 C00003025 0 / 0
P11309 Serine/threonine-protein kinase pim-1 Pim C00003025 0 / 0
O00444 Serine/threonine-protein kinase PLK4 PLK serine/threonine protein kinase subfamily C00003025 0 / 0
Q9NQU5 Serine/threonine-protein kinase PAK 6 STE serine/threonine protein kinase PAKB subfamily C00003025 0 / 0
O75828 Carbonyl reductase [NADPH] 3 Enzyme C00003025 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00003025 2 / 3
Q13188 Serine/threonine-protein kinase 3 STE serine/threonine protein kinase MST subfamily C00003025 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00003025 0 / 0
P07332 Tyrosine-protein kinase Fes/Fps Fer C00003025 0 / 0
P16152 Carbonyl reductase [NADPH] 1 Enzyme C00003025 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00003025 0 / 1
P10145 Interleukin-8 Secreted protein C00003025 0 / 0
Q99683 Mitogen-activated protein kinase kinase kinase 5 Ste11 C00003025 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00003025 0 / 1
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00003025 5 / 3
P52564 Dual specificity mitogen-activated protein kinase kinase 6 Ste7 C00003025 0 / 0
Q96RI1 Bile acid receptor NR1H4 C00003025 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00003025 0 / 0
O14976 Cyclin-G-associated kinase NAK serine/threonine protein kinase subfamily C00003025 0 / 0
O94804 Serine/threonine-protein kinase 10 STE serine/threonine protein kinase SLK subfamily C00003025 1 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00003025 3 / 3
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00003025 2 / 2
P51449 Nuclear receptor ROR-gamma Nuclear hormone receptor subfamily 1 group F member 3 C00003025 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00003025 0 / 0
P03372 Estrogen receptor NR3A1 C00003025 1 / 1
P16050 Arachidonate 15-lipoxygenase Enzyme C00003025 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003025 0 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00003025 0 / 0
P10275 Androgen receptor NR3C4 C00003025 3 / 4
Q9HCP0 Casein kinase I isoform gamma-1 Ck1 C00003025 0 / 0
Q86V86 Serine/threonine-protein kinase pim-3 Pim C00003025 0 / 0
P07900 Heat shock protein HSP 90-alpha Other cytosolic protein C00003025 0 / 0
P08238 Heat shock protein HSP 90-beta Other cytosolic protein C00003025 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00003025 1 / 1

163 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00003025
1244 ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP ATP-binding cassette, sub-family C (CFTR/MRP), member 2 C00003025
8714 ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 C00003025
9429 ABCG2, ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1 ATP-binding cassette, sub-family G (WHITE), member 2 C00003025
1238 ACKR2, CCBP2, CCR10, CCR9, CMKBR9, D6, hD6 atypical chemokine receptor 2 C00003025
56999 ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 C00003025
249 ALPL, AP-TNAP, APTNAP, HOPS, TNAP, TNSALP alkaline phosphatase, liver/bone/kidney (EC:3.1.3.1) C00003025
251 ALPPL2, ALPG, ALPPL, GCAP alkaline phosphatase, placental-like 2 (EC:3.1.3.1) C00003025
64682 ANAPC1, APC1, MCPR, TSG24 anaphase promoting complex subunit 1 C00003025
55107 ANO1, DOG1, ORAOV2, TAOS2, TMEM16A anoctamin 1, calcium activated chloride channel C00003025
348 APOE, AD2, LDLCQ5, LPG apolipoprotein E C00003025
367 AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM androgen receptor C00003025
427 ASAH1, AC, ACDase, ASAH, PHP, PHP32, SMAPME N-acylsphingosine amidohydrolase (acid ceramidase) 1 (EC:3.5.1.23) C00003025
80150 ASRGL1, ALP, ALP1, CRASH asparaginase like 1 (EC:3.5.1.1 3.4.19.5) C00003025
64756 ATPAF1, ATP11, ATP11p ATP synthase mitochondrial F1 complex assembly factor 1 C00003025
581 BAX, BCL2L4 BCL2-associated X protein C00003025
636 BICD1, BICD bicaudal D homolog 1 (Drosophila) C00003025
662 BNIP1, NIP1, SEC20, TRG-8 BCL2/adenovirus E1B 19kDa interacting protein 1 C00003025
79680 C22orf29, BOP chromosome 22 open reading frame 29 C00003025
50854 C6orf48, D6S57, G8 chromosome 6 open reading frame 48 C00003025
760 CA2, CA-II, CAC, CAII, Car2 carbonic anhydrase II (EC:4.2.1.1) C00003025
91768 CABLES1, CABL1, CABLES, HsT2563, IK3-1 Cdk5 and Abl enzyme substrate 1 C00003025
10753 CAPN9, GC36, nCL-4 calpain 9 (EC:3.4.22.-) C00003025
833 CARS, CARS1, CYSRS, MGC:11246 cysteinyl-tRNA synthetase (EC:6.1.1.16) C00003025
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00003025
863 CBFA2T3, ETO2, MTG16, MTGR2, ZMYND4 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 C00003025
1052 CEBPD, C/EBP-delta, CELF, CRP3, NF-IL6-beta CCAAT/enhancer binding protein (C/EBP), delta C00003025
1081 CGA, CG-ALPHA, FSHA, GPHA1, GPHa, HCG, LHA, TSHA glycoprotein hormones, alpha polypeptide C00003025
1082 CGB, CGB3, CGB5, CGB7, CGB8, hCGB chorionic gonadotropin, beta polypeptide C00003025
494143 CHAC2 ChaC, cation transport regulator homolog 2 (E. coli) C00003025
84518 CNFN, PLAC8L2 cornifelin C00003025
23603 CORO1C, HCRNN4 coronin, actin binding protein, 1C C00003025
51596 CUTA, ACHAP, C6orf82 cutA divalent cation tolerance homolog (E. coli) C00003025
1523 CUX1, CASP, CDP, CDP/Cut, CDP1, COY1, CUTL1, CUX, Clox, Cux/CDP, GOLIM6, Nbla10317, p100, p110, p200, p75 cut-like homeobox 1 C00003025
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00003025
1588 CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) C00003025
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00003025
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00003025
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00003025
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00003025
308585 C00003025
9249 DHRS3, DD83.1, RDH17, Rsdr1, SDR1, SDR16C1, retSDR1 dehydrogenase/reductase (SDR family) member 3 (EC:1.1.1.300) C00003025
55715 DOK4 docking protein 4 C00003025
1891 ECH1, HPXEL enoyl CoA hydratase 1, peroxisomal C00003025
2037 EPB41L2, 4.1-G, 4.1G erythrocyte membrane protein band 4.1-like 2 C00003025
55040 EPN3 epsin 3 C00003025
2065 ERBB3, ErbB-3, HER3, LCCS2, MDA-BF-1, c-erbB-3, c-erbB3, erbB3-S, p180-ErbB3, p45-sErbB3, p85-sErbB3 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3 (EC:2.7.10.1) C00003025
2071 ERCC3, BTF2, GTF2H, RAD25, TFIIH, XPB excision repair cross-complementing rodent repair deficiency, complementation group 3 (EC:3.6.4.12) C00003025
121506 ERP27, C12orf46, PDIA8 endoplasmic reticulum protein 27 C00003025
83715 ESPN, DFNB36 espin C00003025
2099 ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 estrogen receptor 1 C00003025
2100 ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 estrogen receptor 2 (ER beta) C00003025
55224 ETNK2, EKI2, HMFT1716 ethanolamine kinase 2 (EC:2.7.1.82) C00003025
11170 FAM107A, DRR1, TU3A family with sequence similarity 107, member A C00003025
64855 FAM129B, C9orf88, MEG-3, MINERVA, OC58, bA356B19.6 family with sequence similarity 129, member B C00003025
252995 FNDC5, FRCP2, irisin fibronectin type III domain containing 5 C00003025
2348 FOLR1, FBP, FOLR folate receptor 1 (adult) C00003025
2297 FOXD1, FKHL8, FREAC4 forkhead box D1 C00003025
2302 FOXJ1, FKHL13, HFH-4, HFH4 forkhead box J1 C00003025
50486 G0S2, RP1-28O10.2 G0/G1switch 2 C00003025
8693 GALNT4, GALNAC-T4, GALNACT4 UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4) (EC:2.4.1.41) C00003025
8811 GALR2, GAL2-R, GALNR2, GALR-2 galanin receptor 2 C00003025
81544 GDPD5, GDE2, PP1665 glycerophosphodiester phosphodiesterase domain containing 5 C00003025
64785 GINS3, PSF3 GINS complex subunit 3 (Psf3 homolog) C00003025
51022 GLRX2, CGI-133, GRX2 glutaredoxin 2 C00003025
2852 GPER1, CEPR, CMKRL2, DRY12, FEG-1, GPCR-Br, GPER, GPR30, LERGU, LERGU2, LyGPR G protein-coupled estrogen receptor 1 C00003025
350383 GPR142, PGR2 G protein-coupled receptor 142 C00003025
9687 GREB1 growth regulation by estrogen in breast cancer 1 C00003025
79792 GSDMD, DF5L, DFNA5L, GSDMDC1 gasdermin D C00003025
145864 HAPLN3, EXLD1, HsT19883 hyaluronan and proteoglycan link protein 3 C00003025
54626 HES2, bHLHb40 hes family bHLH transcription factor 2 C00003025
3017 HIST1H2BD, H2B.1B, H2B/b, H2BFB, HIRIP2, dJ221C16.6 histone cluster 1, H2bd C00003025
3096 HIVEP1, CIRIP, CRYBP1, MBP-1, PRDII-BF1, Schnurri-1, ZAS1, ZNF40, ZNF40A human immunodeficiency virus type I enhancer binding protein 1 C00003025
3151 HMGN2, HMG17 high mobility group nucleosomal binding domain 2 C00003025
3303 HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1 heat shock 70kDa protein 1A C00003025
3315 HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27 heat shock 27kDa protein 1 C00003025
10410 IFITM3, 1-8U, DSPA2b, IP15 interferon induced transmembrane protein 3 C00003025
3489 IGFBP6, IBP6 insulin-like growth factor binding protein 6 C00003025
3566 IL4R, CD124, IL-4RA, IL4RA interleukin 4 receptor C00003025
3615 IMPDH2, IMPD2, IMPDH-II IMP (inosine 5'-monophosphate) dehydrogenase 2 (EC:1.1.1.205) C00003025
9670 IPO13, IMP13, KAP13, LGL2, RANBP13 importin 13 C00003025
3705 ITPK1, ITRPK1 inositol-tetrakisphosphate 1-kinase (EC:2.7.1.134 2.7.1.159) C00003025
3754 KCNF1, IK8, KCNF, KV5.1, kH1 potassium voltage-gated channel, subfamily F, member 1 C00003025
3762 KCNJ5, CIR, GIRK4, KATP1, KIR3.4, LQT13 potassium inwardly-rectifying channel, subfamily J, member 5 C00003025
222658 KCTD20, C6orf69, dJ108K11.3 potassium channel tetramerization domain containing 20 C00003025
9768 NS5ATP9, OEATC, OEATC-1, OEATC1, PAF, PAF15, p15(PAF), p15/PAF, p15PAF KIAA0101 C00003025
3872 KRT17, K17, PC, PC2, PCHC1 keratin 17 C00003025
7044 LEFTY2, EBAF, LEFTA, LEFTYA, TGFB4 left-right determination factor 2 C00003025
3956 LGALS1, GAL1, GBP lectin, galactoside-binding, soluble, 1 C00003025
64748 LPPR2, PRG4 lipid phosphate phosphatase-related protein type 2 (EC:3.1.3.4) C00003025
5603 MAPK13, MAPK_13, MAPK-13, PRKM13, SAPK4, p38delta mitogen-activated protein kinase 13 (EC:2.7.11.24) C00003025
4192 MDK, ARAP, MK, NEGF2 midkine (neurite growth-promoting factor 2) C00003025
4222 MEOX1, KFS2, MOX1 mesenchyme homeobox 1 C00003025
4233 MET, AUTS9, HGFR, RCCP2, c-Met met proto-oncogene (EC:2.7.10.1) C00003025
4240 MFGE8, BA46, EDIL1, HMFG, HsT19888, MFG-E8, MFGM, OAcGD3S, SED1, SPAG10, hP47 milk fat globule-EGF factor 8 protein C00003025
9927 MFN2, CMT2A, CMT2A2, CPRP1, HSG, MARF mitofusin 2 C00003025
79083 MLPH, SLAC2-A melanophilin C00003025
4477 MSMB, HPC13, IGBF, MSP, MSPB, PN44, PRPS, PSP, PSP-94, PSP57, PSP94 microseminoprotein, beta- C00003025
400746 NCMAP, C1orf130, MP11 noncompact myelin associated protein C00003025
10499 NCOA2, GRIP1, KAT13C, NCoA-2, SRC2, TIF2, bHLHe75 nuclear receptor coactivator 2 C00003025
252969 NEIL2, NEH2, NEI2 nei endonuclease VIII-like 2 (E. coli) (EC:4.2.99.18) C00003025
25791 NGEF, ARHGEF27, EPHEXIN neuronal guanine nucleotide exchange factor C00003025
8856 NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR nuclear receptor subfamily 1, group I, member 2 C00003025
8204 NRIP1, RIP140 nuclear receptor interacting protein 1 C00003025
4902 NRTN, NTN neurturin C00003025
10439 OLFM1, AMY, NOE1, NOELIN1, OlfA olfactomedin 1 C00003025
56944 OLFML3, HNOEL-iso, OLF44 olfactomedin-like 3 C00003025
10081 PDCD7, ES18, HES18 programmed cell death 7 C00003025
5208 PFKFB2, PFK-2/FBPase-2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 (EC:2.7.1.105 3.1.3.46) C00003025
5241 PGR, NR3C3, PR progesterone receptor C00003025
51131 PHF11, APY, BCAP, IGEL, IGER, IGHER, NY-REN-34, NYREN34 PHD finger protein 11 C00003025
5292 PIM1, PIM pim-1 oncogene (EC:2.7.11.1) C00003025
23236 PLCB1, EIEE12, PI-PLC, PLC-154, PLC-I, PLC154, PLCB1A, PLCB1B phospholipase C, beta 1 (phosphoinositide-specific) (EC:3.1.4.11) C00003025
84898 PLXDC2, TEM7R plexin domain containing 2 C00003025
5432 POLR2C, RPB3, RPB31, hRPB33, hsRPB3 polymerase (RNA) II (DNA directed) polypeptide C, 33kDa (EC:2.7.7.6) C00003025
63978 PRDM14, PFM11 PR domain containing 14 C00003025
5576 PRKAR2A, PKR2, PRKAR2 protein kinase, cAMP-dependent, regulatory, type II, alpha (EC:2.7.11.1) C00003025
11098 PRSS23, SIG13, SPUVE, ZSIG13 protease, serine, 23 C00003025
55647 RAB20 RAB20, member RAS oncogene family C00003025
31818 C00003025
221662 RBM24, RNPC6, dJ259A10.1 RNA binding motif protein 24 C00003025
5947 RBP1, CRABP-I, CRBP, CRBP1, CRBPI, RBPC retinol binding protein 1, cellular C00003025
26150 RIBC2, C22orf11 RIB43A domain with coiled-coils 2 C00003025
116028 RMI2, BLAP18, C16orf75 RecQ mediated genome instability 2 C00003025
10325 RRAGB, RAGB, bA465E19.1 Ras-related GTP binding B C00003025
1903 S1PR3, EDG-3, EDG3, LPB3, S1P3 sphingosine-1-phosphate receptor 3 C00003025
45384 C00003025
54581 SCAND2P, SCAND2 SCAN domain containing 2 pseudogene C00003025
83443 SF3B5, SF3b10, Ysf3 splicing factor 3b, subunit 5, 10kDa C00003025
6477 SIAH1, SIAH1A siah E3 ubiquitin protein ligase 1 (EC:6.3.2.-) C00003025
6510 SLC1A5, AAAT, ASCT2, ATBO, M7V1, M7VS1, R16, RDRC solute carrier family 1 (neutral amino acid transporter), member 5 C00003025
1317 SLC31A1, COPT1, CTR1 solute carrier family 31 (copper transporter), member 1 C00003025
6520 SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE solute carrier family 3 (amino acid transporter heavy chain), member 2 C00003025
54946 SLC41A3, SLC41A1-L2 solute carrier family 41, member 3 C00003025
6533 SLC6A6, TAUT solute carrier family 6 (neurotransmitter transporter), member 6 C00003025
8140 SLC7A5, 4F2LC, CD98, D16S469E, E16, LAT1, MPE16, hLAT1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 C00003025
90864 SPSB3, C16orf31, SSB3 splA/ryanodine receptor domain and SOCS box containing 3 C00003025
6713 SQLE squalene epoxidase (EC:1.14.13.132) C00003025
136853 SRCRB4D, S4D-SRCRB, SRCRB-S4D, SSC4D scavenger receptor cysteine rich domain containing, group B (4 domains) C00003025
6783 SULT1E1, EST, EST-1, ST1E1, STE sulfotransferase family 1E, estrogen-preferring, member 1 (EC:2.8.2.4) C00003025
7039 TGFA, TFGA transforming growth factor, alpha C00003025
7057 THBS1, THBS, THBS-1, TSP, TSP-1, TSP1 thrombospondin 1 C00003025
26277 TINF2, DKCA3, TIN2 TERF1 (TRF1)-interacting nuclear factor 2 C00003025
80757 TMEM121, hole transmembrane protein 121 C00003025
113452 TMEM54, BCLP, CAC-1, CAC1 transmembrane protein 54 C00003025
8718 TNFRSF25, APO-3, DDR3, DR3, LARD, TNFRSF12, TR3, TRAMP, WSL-1, WSL-LR tumor necrosis factor receptor superfamily, member 25 C00003025
7138 TNNT1, ANM, NEM5, STNT, TNT, TNTS troponin T type 1 (skeletal, slow) C00003025
8848 TSC22D1, Ptg-2, TGFB1I4, TSC22 TSC22 domain family, member 1 C00003025
25987 TSKU, E2IG4, LRRC54, TSK tsukushi, small leucine rich proteoglycan C00003025
83882 TSPAN10, OCSP tetraspanin 10 C00003025
23554 TSPAN12, EVR5, NET-2, NET2, TM4SF12 tetraspanin 12 C00003025
54658 UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17) C00003025
54575 UGT1A10, UDPGT, UGT-1J, UGT1-10, UGT1.10, UGT1J UDP glucuronosyltransferase 1 family, polypeptide A10 (EC:2.4.1.17) C00003025
54577 UGT1A7, UDPGT, UDPGT_1-7, UGT-1G, UGT1-07, UGT1.7, UGT1G UDP glucuronosyltransferase 1 family, polypeptide A7 (EC:2.4.1.17) C00003025
54576 UGT1A8, UDPGT, UDPGT_1-8, UGT-1H, UGT1-08, UGT1.8, UGT1A8S, UGT1H UDP glucuronosyltransferase 1 family, polypeptide A8 (EC:2.4.1.17) C00003025
54600 UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17) C00003025
84135 UTP15, NET21 UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae) C00003025
79609 VCPKMT, C14orf138, METTL21D, VCP-KMT valosin containing protein lysine (K) methyltransferase C00003025
7476 WNT7A wingless-type MMTV integration site family, member 7A C00003025
11060 WWP2, AIP2, WWp2-like WW domain containing E3 ubiquitin protein ligase 2 C00003025
342357 ZKSCAN2, ZNF694, ZSCAN31, ZSCAN34 zinc finger with KRAB and SCAN domains 2 C00003025
9203 ZMYM3, DXS6673E, MYM, XFIM, ZNF198L2, ZNF261 zinc finger, MYM-type 3 C00003025
51364 ZMYND10, BLU, FLU zinc finger, MYND-type containing 10 C00003025

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (50)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
%606641 Body mass index; bmi P37231
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#609338 Carotid intimal medial thickness 1 P37231
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#119900 Digital clubbing, isolated congenital P15428
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#133239 Esophageal cancer P04637
#615363 Estrogen resistance; estrr P03372
#137800 Glioma susceptibility 1; glm1 P37231
#232300 Glycogen storage disease ii P10253
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P04637
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#601665 Obesity P37231
#260500 Papilloma of choroid plexus; cpp P04637
#275210 Restrictive dermopathy, lethal P02545
#609620 Short qt syndrome 1; sqt1 Q12809
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#273300 Testicular germ cell tumor; tgct O94804
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (70)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
P37231 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00026 Endometrial Cancer P03372 (marker)
P04637 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
P37231 (related)
H00033 Adrenal carcinoma P04637 (related)
H00036 Osteosarcoma P04637 (related)
P08684 (marker)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)

Diseases related to CTD interactions

5 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D052776 Female Urogenital Diseases C00003025
D009336 Necrosis C00003025
D011248 Pregnancy Complications C00003025
D011297 Prenatal Exposure Delayed Effects C00003025
D011629 Puberty, Precocious C00003025