Litsea verbena
Species
KNApSAcK Entry
| Organism name | Litsea verbena |
|---|---|
| Genus | Litsea |
| Family | Lauraceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Litsea |
|---|---|
| Linked NCBI taxonomy ID | 22042 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Lauraceae |
|---|---|
| ID | 3433 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | Magnoliophyta |
|---|---|
| ID | 3398 |
Metabolite list (3)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003035
|
Geranial
/ (E)-alpha-Citral |
CHEMBL1080997
|
6 / 7 / 9 | No. 1575 | No. 34 |
|
||
|
C00003036
|
Neral
/ Citral Z |
CHEMBL1080997
|
6 / 7 / 9 | No. 1575 | No. 34 |
|
||
|
C00035822
|
Citral (E/Z)
|
CHEMBL1080997
|
C007076
|
6 / 7 / 9 | 7 / 1 | No. 1575 | No. 34 |
|
Human Protein / Gene in interactions
6 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10828 | Thyroid hormone receptor beta | NR1A2 | C00003035 C00003036 C00035822 | 3 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003035 C00003036 C00035822 | 0 / 0 |
| O00519 | Fatty-acid amide hydrolase 1 | Enzyme | C00003035 C00003036 C00035822 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00003035 C00003036 C00035822 | 3 / 4 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00003035 C00003036 C00035822 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00003035 C00003036 C00035822 | 1 / 4 |
7 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1646 | AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8 | aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357) |
C00035822
|
| 1555 | CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450 | cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1) |
C00035822
|
| 2099 | ESR1, ER, ESR, ESRA, ESTRR, Era, NR3A1 | estrogen receptor 1 |
C00035822
|
| 2100 | ESR2, ER-BETA, ESR-BETA, ESRB, ESTRB, Erb, NR3A2 | estrogen receptor 2 (ER beta) |
C00035822
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00035822
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00035822
|
| 23764 | MAFF, U-MAF, hMafF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F |
C00035822
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (7)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
| #188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
| #274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
| #145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
KEGG DISEASE (9)
| KEGG | name | UniProt |
|---|---|---|
| H00024 | Prostate cancer |
P10275
(related)
|
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|