Species

KNApSAcK Entry

Organism name Osyris tenuifolia
Genus Osyris
Family Santalaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Osyris
Linked NCBI taxonomy ID 23412
Linked level genus

Family

Family in NCBI taxonomy Santalaceae
ID 3958

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class eudicotyledons
ID 71240

Metabolite list (22)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003111 External link 512 Cedr-8-ene
/ (-)-Cedrene
/ alpha-Cedrene
No. 149 No. 38
C00021580 External link 512 beta-Acoradiene
No. 151 No. 38
C00011617 External link 512 AR-Curcumene
/ (R)-(-)-alpha-Curcumene
CHEMBL469717
No. 456 No. 38
C00035098 External link 512 epi-alpha-Bisabolol
/ (-)-epi-alpha-Bisabolol
CHEMBL519167
CHEMBL491186
CHEMBL477832
CHEMBL1096927
CHEMBL1171719
CHEMBL1561544
CHEMBL2104360
8 / 4 / 13 No. 541 No. 38
C00007242 External link 512 beta-Bisabolene
/ l-beta-Bisabolene
/ (-)-beta-Bisabolene
CHEMBL444389
CHEMBL1077088
CHEMBL2001434
No. 701 No. 38
C00011638 External link 512 (-)-(E)-Lanceol
CHEMBL443875
No. 701 No. 38
C00035439 External link 512 (S)-(Z)-Lanceol
CHEMBL443875
No. 701 No. 38
C00021850 External link 512 alpha-Santalene
No. 992 No. 38
C00035245 External link 512 ar-Tenuifolene
/ (-)-ar-Tenuifolene
No. 1216
C00035440 External link 512 (Z)-alpha-bisabolene
No. 1323 No. 38
C00007632 External link 512 (E)-alpha-Bisabolene
No. 1323 No. 38
C00035441 External link 512 (Z)-gamma-Bisabolene
No. 1469 No. 38
C00021904 External link 512 trans-beta-Bergamotene
No. 1653 No. 38
C00021903 External link 512 alpha-trans-Bergamotene
/ trans-alpha-Bergamotene
No. 1653 No. 38
C00029970 External link 512 cis-alpha-Bergamotene
No. 1653 No. 38
C00030346 External link 512 gamma-Curcumene
No. 1788 No. 38
C00003181 External link 512 beta-Santalene
No. 1957 No. 38
C00035606 External link 512 epi-beta-Santalene
No. 1957 No. 38
C00035764 External link 512 Tenuifolene
/ (-)-Tenuifolene
No. 2043
C00035673 External link 512 Lanceoloxide
/ (-)-Lanceoloxide
No. 4042
C00035570 External link 512 Cyclosantalal
No. 4794
C00035608 External link 512 Epicyclosantalal
/ epi-Cyclosantalal
No. 4794

Human Protein / Gene in interactions

8 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00035098 0 / 3
P40763 Signal transducer and activator of transcription 3 Transcription Factor C00035098 1 / 2
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00035098 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00035098 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00035098 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00035098 0 / 1
O00255 Menin Unclassified protein C00035098 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00035098 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255

KEGG DISEASE (13)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00036 Osteosarcoma P08684 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00016 Oral cancer P40763 (related)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)