Species

KNApSAcK Entry

Organism name Frullania rostrata
Genus Frullania
Family Jubulaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Frullania rostrata
Linked NCBI taxonomy ID 642359
Linked level species

Family

Family in NCBI taxonomy Frullaniaceae
ID 400721

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Embryophyta
ID 3193

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003240 External link 512 Costunolide
CHEMBL86416
CHEMBL190377
CHEMBL1575037
C002602
10 / 7 / 15 0 / 3 No. 107 No. 38
C00012168 External link 512 Dihydrocostunolide
/ (+)-Dihydrocostunolide
/ 11betaH,13-Dihydrocostunolide
CHEMBL499003
No. 237
C00012006 External link 512 Saussurea lactone
/ (all-S)-Hexahydro-7-isopropenyl-3,6-dimethyl-6-vinyl-2(3H)-benzofuranone
No. 1377

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00003240 0 / 3
P11473 Vitamin D3 receptor NR1I1 C00003240 2 / 3
Q04206 Transcription factor p65 Transcription Factor C00003240 0 / 0
P03372 Estrogen receptor NR3A1 C00003240 1 / 1
P46063 ATP-dependent DNA helicase Q1 Enzyme C00003240 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00003240 1 / 1
O00255 Menin Unclassified protein C00003240 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00003240 1 / 2
Q00653 Nuclear factor NF-kappa-B p100 subunit Transcription Factor C00003240 0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00003240 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (7)

OMIM preferred title UniProt
#615363 Estrogen resistance; estrr P03372
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (15)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00026 Endometrial Cancer P03372 (marker)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)

Diseases related to CTD interactions

3 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003921 Diabetes Mellitus, Experimental C00003240
D006943 Hyperglycemia C00003240
D011230 Precancerous Conditions C00003240