Species

KNApSAcK Entry

Organism name Xanthium canadense Mill.
Genus Xanthium
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Xanthium
Linked NCBI taxonomy ID 36590
Linked level genus

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (3)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003758 External link 512 Alnulin
/ Tiliadin
/ Skimmiol
/ Taraxerol
CHEMBL511822
CHEMBL470462
C005802
No. 13 No. 51
C00003306 External link 512 Isohelenin
/ Isoalantolactone
/ Isoallantolactone
CHEMBL273254
CHEMBL137803
CHEMBL1410671
CHEMBL1451900
CHEMBL2000732
C032787
6 / 4 / 5 No. 69 No. 38
C00032288 External link 512 Taraxerol acetate
C404196
No. 177

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00003306 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00003306 0 / 1
P03372 Estrogen receptor NR3A1 C00003306 1 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00003306 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003306 0 / 1
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00003306 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (4)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#615363 Estrogen resistance; estrr P03372
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8

KEGG DISEASE (5)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)