Salvia carnosa
Species
KNApSAcK Entry
| Organism name | Salvia carnosa |
|---|---|
| Genus | Salvia |
| Family | Labiatae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Salvia |
|---|---|
| Linked NCBI taxonomy ID | 21880 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Lamiaceae |
|---|---|
| ID | 4136 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003410
|
Carnosol
|
CHEMBL218693
CHEMBL1514916 |
C068623
|
17 / 17 / 17 | 12 / 0 | No. 734 | No. 40 |
|
Human Protein / Gene in interactions
17 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | C00003410 | 1 / 1 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003410 | 2 / 0 |
| Q9Y5X4 | Photoreceptor-specific nuclear receptor | NR2E3 | C00003410 | 2 / 2 |
| P37840 | Alpha-synuclein | Unclassified protein | C00003410 | 4 / 2 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00003410 | 2 / 3 |
| P39748 | Flap endonuclease 1 | Enzyme | C00003410 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00003410 | 0 / 0 |
| P11413 | Glucose-6-phosphate 1-dehydrogenase | Enzyme | C00003410 | 1 / 2 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00003410 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00003410 | 0 / 0 |
| P16233 | Pancreatic triacylglycerol lipase | Hydrolase | C00003410 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00003410 | 0 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00003410 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00003410 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00003410 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00003410 | 2 / 5 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00003410 | 1 / 2 |
12 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00003410
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00003410
|
| 1545 | CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) |
C00003410
|
| 2729 | GCLC, GCL, GCS, GLCL, GLCLC | glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) |
C00003410
|
| 2730 | GCLM, GLCLR | glutamate-cysteine ligase, modifier subunit (EC:6.3.2.2) |
C00003410
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00003410
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00003410
|
| 3551 | IKBKB, IKK-beta, IKK2, IKKB, NFKBIKB | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta (EC:2.7.11.10) |
C00003410
|
| 4780 | NFE2L2, NRF2 | nuclear factor, erythroid 2-like 2 |
C00003410
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00003410
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00003410
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00003410
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (17)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300908 | Anemia, nonspherocytic hemolytic, due to g6pd deficiency |
P11413
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #268100 | Enhanced s-cone syndrome; escs |
Q9Y5X4
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #611131 | Retinitis pigmentosa 37; rp37 |
Q9Y5X4
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (17)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00101 | Other phagocyte defects |
P11413
(related)
|
| H00668 | Anemia due to disorders of glutathione metabolism |
P11413
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00527 | Retinitis pigmentosa (RP) |
Q9Y5X4
(related)
|
| H00805 | Vitreoretinal degeneration |
Q9Y5X4
(related)
|