Species

KNApSAcK Entry

Organism name Schefflera capitata
Genus Schefflera
Family Araliaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Schefflera
Linked NCBI taxonomy ID 46414
Linked level genus

Family

Family in NCBI taxonomy Araliaceae
ID 4050

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003516 External link 512 Echinocystic acid
CHEMBL230128
CHEMBL464557
CHEMBL1395408
CHEMBL1559201
C022999
5 / 0 / 1 8 / 2 No. 13 No. 51

Human Protein / Gene in interactions

5 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P30559 Oxytocin receptor Vasopressin and oxytocin receptor C00003516 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00003516 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00003516 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00003516 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003516 0 / 1

8 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
581 BAX, BCL2L4 BCL2-associated X protein C00003516
637 BID, FP497 BH3 interacting domain death agonist C00003516
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00003516
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00003516
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00003516
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00003516
56616 DIABLO, DFNA64, SMAC diablo, IAP-binding mitochondrial protein C00003516
331 XIAP, API3, BIRC4, IAP-3, ILP1, MIHA, XLP2, hIAP-3, hIAP3 X-linked inhibitor of apoptosis C00003516

Related Diseases

Diseases related to proteins in ChEMBL interactions

KEGG DISEASE (1)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D017202 Myocardial Ischemia C00003516
D009369 Neoplasms C00003516